LARS gene related symptoms and diseases
All the information presented here about the LARS gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,HGNC,ORPHANET,OMIM, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to LARS gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Seizures | Very Common - Between 80% and 100% cases |
| Hepatic failure | Very Common - Between 80% and 100% cases |
| Acute hepatic failure | Very Common - Between 80% and 100% cases |
| Macrocytic anemia | Very Common - Between 80% and 100% cases |
| Microcytic anemia | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with LARS gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Long fingers
- Abnormality of the coagulation cascade
- Delayed gross motor development
- Full cheeks
- Hepatic steatosis
- Lactic acidosis
- Global developmental delay
- Abnormality of the liver
And 9 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to LARS gene
Here you will find a list of rare diseases related to the LARS. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
ACUTE INFANTILE LIVER FAILURE-MULTISYSTEMIC INVOLVEMENT SYNDROME
Description
Acute infantile liver failure-multisystemic involvement syndrome is a rare, genetic, parenchymal hepatic disease characterized by acute liver failure, that occurs in the first year of life, which manifests with failure to thrive, hypotonia, moderate global developmental delay, seizures, abnormal liver function tests, microcytic anemia and elevated serum lactate. Other associated features include hepatosteatosis and fibrosis, abnormal brain morphology, and renal tubulopathy. Minor illness exacerbates deterioration of liver failure.
Most common symptoms of ACUTE INFANTILE LIVER FAILURE-MULTISYSTEMIC INVOLVEMENT SYNDROME
- Seizures
- Global developmental delay
- Generalized hypotonia
- Microcephaly
- Failure to thrive
More info about ACUTE INFANTILE LIVER FAILURE-MULTISYSTEMIC INVOLVEMENT SYNDROME
Search interest in LARS
Potential gene panels for LARS gene
Infantile Liver Failure Syndrome Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Infantile Liver Failure Syndrome Sequencing Panel with CNV Detection that also includes the following genes: NBAS LARS
More info about this panel United States.
Infantile Liver Failure Syndrome via LARS Gene Sequencing with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics
This panel specifically test the LARS gene.
More info about this panel United States.
Neuropathy Panel
Germany.
By MGZ Medical Genetics Center Neuropathy that also includes the following genes: SACS SCN10A SCN11A SCN9A SH3BP4 SLC12A6 SOD1 SPG11 ATL1 SPAST
More info about this panel Germany.
Neurogenetic Disorders - panels Panel
Germany.
By MGZ Medical Genetics Center Neurogenetic Disorders - panels that also includes the following genes: BCS1L RTN2 RYR1 SACS SCN1A SCN1B SCN2A SCN8A SCO1 SCO2
More info about this panel Germany.
Single gene testing LARS Panel
Germany.
By CeGaT GmbH
This panel specifically test the LARS gene.
More info about this panel Germany.
LARS Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the LARS gene.
More info about this panel United States.
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