HAND2 gene related symptoms and diseases

All the information presented here about the HAND2 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,NCBIGENE,HGNC, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to HAND2 gene

Symptoms // Phenotype % Cases
Growth delay Very Common - Between 80% and 100% cases
Double outlet right ventricle Very Common - Between 80% and 100% cases
Sinusitis Very Common - Between 80% and 100% cases
Increased body weight Very Common - Between 80% and 100% cases
Easy fatigability Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with HAND2 gene alterations may also develop some of the following symptoms and phenotypes:
  • Commonly - More than 50% cases

  • Clubbing
  • Heart murmur
  • Preauricular pit
  • Polycythemia
  • Underdeveloped supraorbital ridges
  • Poor appetite
  • Hyperventilation
  • Truncus arteriosus

And 39 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to HAND2 gene

Here you will find a list of rare diseases related to the HAND2. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


TETRALOGY OF FALLOT


Description

Tetralogy of Fallot is a congenital cardiac malformation that consists of an interventricular communication, also known as a ventricular septal defect, obstruction of the right ventricular outflow tract, override of the ventricular septum by the aortic root, and right ventricular hypertrophy.

Most common symptoms of TETRALOGY OF FALLOT

  • Growth delay
  • Muscle weakness
  • Cryptorchidism
  • Anemia
  • Brachydactyly


More info about TETRALOGY OF FALLOT

SOURCES: OMIM MESH ORPHANET


Potential gene panels for HAND2 gene

Cardiovascular Diseases_General Panel Panel

Spain.

By Health in Code Cardiovascular Diseases_General Panel that also includes the following genes: RIT1 MRPL3 RRAS RYR1 RYR2 SAR1B BLK SCN10A SCN1B SCN2B

More info about this panel

Congenital heart diseases Panel Panel

Spain.

By Health in Code Congenital heart diseases Panel that also includes the following genes: BRAF SOS1 TBX1 TBX20 TBX5 TFAP2B TNNI3 MED12 ZIC3 ACTA2

More info about this panel

HAND2 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the HAND2 gene.

More info about this panel


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