GPD1L gene related symptoms and diseases

All the information presented here about the GPD1L gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,HGNC,OMIM,NCBIGENE, Mendelian Rare Disease Search Engine.

Table of contents:

Main symptoms and clinical features
Other symptoms and clinical features
Related Diseases
Current trends
Suitable testing panels

Top 5 symptoms and clinical features associated to GPD1L gene

Symptoms // Phenotype	% Cases
Ventricular arrhythmia	Very Common - Between 80% and 100% cases
Arrhythmia	Very Common - Between 80% and 100% cases
ST segment elevation	Very Common - Between 80% and 100% cases
Sudden cardiac death	Very Common - Between 80% and 100% cases
Bundle branch block	Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with GPD1L gene alterations may also develop some of the following symptoms and phenotypes:

Commonly - More than 50% cases
Syncope
Prolonged PR interval
Right bundle branch block
Ventricular fibrillation
Not very common - Between 30% and 50% cases
Seizures
Prolonged QRS complex
Abnormal electrophysiology of sinoatrial node origin
Ventricular preexcitation

And 20 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to GPD1L gene

Here you will find a list of rare diseases related to the GPD1L. You can also use our tool to get a more accurate diagnosis based on your current symptoms.

BRUGADA SYNDROME

Alternate names

BRUGADA SYNDROME Is also known as dream disease, idiopathic ventricular fibrillation, brugada type, sudden unexplained nocturnal death syndrome, bangungut, pokkuri death syndrome, sunds

Description

Brugada syndrome (BrS) manifests with ST segment elevation in right precordial leads (V1 to V3), incomplete or complete right bundle branch block, and susceptibility to ventricular tachyarrhythmia and sudden death. BrS is an electrical disorder without overt myocardial abnormalities.

Most common symptoms of BRUGADA SYNDROME

Seizures
Pain
Arrhythmia
Vertigo
Tachycardia

More info about BRUGADA SYNDROME

SOURCES: ORPHANET OMIM

BRUGADA SYNDROME 2; BRGDA2

Description

Brugada syndrome is characterized by an ST segment elevation in the right precordial electrocardiogram leads (so-called type 1 ECG) and a high incidence of sudden death in patients with structurally normal hearts. The syndrome typically manifests during adulthood, with a mean age of sudden death of 41 +/- 15 years, but also occurs in infants and children (summary by Antzelevitch et al., 2005).For a discussion of genetic heterogeneity of Brugada syndrome, see BRGDA1 (OMIM ).

Most common symptoms of BRUGADA SYNDROME 2; BRGDA2

Arrhythmia
Sudden cardiac death
Syncope
Shock
Ventricular arrhythmia

More info about BRUGADA SYNDROME 2; BRGDA2

SOURCES: OMIM MESH

Search interest in GPD1L

Potential gene panels for GPD1L gene

Brugada Syndrome Panel Panel

United States.

By Greenwood Genetic Center Diagnostic Laboratories Greenwood Genetic Center Brugada Syndrome Panel that also includes the following genes: SCN1B SCN2B SCN5A CACNA1C CACNB2 SLMAP HCN4 TRPM4 SCN3B GPD1L

GPD1L gene related symptoms and diseases

Top 5 symptoms and clinical features associated to GPD1L gene

Other less frequent symptoms and clinical features

Commonly - More than 50% cases

Not very common - Between 30% and 50% cases

Accelerate your rare disease diagnosis with us

Rare diseases associated to GPD1L gene

BRUGADA SYNDROME

Alternate names

Description

Most common symptoms of BRUGADA SYNDROME

BRUGADA SYNDROME 2; BRGDA2

Description

Most common symptoms of BRUGADA SYNDROME 2; BRGDA2

Search interest in GPD1L

Potential gene panels for GPD1L gene

Brugada Syndrome Panel Panel

Comprehensive Cardiac Panel Panel

Cardiomyopathy Panel Panel

Brugada Syndrome Panel

Comprehensive Arrhythmias Panel Panel

Brugada Syndrome Panel Panel

Cardiac Channelopathy Panel Panel

GPD1L Panel

Cardiomyopathy and Arrhythmia Panel, Sequencing and Deletion/Duplication Panel

Brugada Syndrome Sequencing Panel Panel

Comprehensive Arrhythmia Panel Panel

CardioNext with TTN Panel

CustomNext: Cardio Panel

RhythmNext Panel

RhythmFirst reflex RhythmNext Panel

Cardiac Arrhythmia NGS Multi-Gene Panel (48 genes), Sequence & CNV analysis Panel

Brugada syndrome (sequence analysis of GPD1L gene) Panel

Brugada syndrome (NGS panel for 7 genes) Panel

Cardiac conduction changes (NGS panel for 27 genes) Panel

Cardiomyopathy and changes in cardiac conduction (NGS panel for 59 genes) Panel

Brugada Syndrome type 2 Panel

Brugada Syndrome via GPD1L Gene Sequencing with CNV Detection Panel

Brugada Syndrome Sequencing Panel with CNV Detection Panel

Comprehensive Cardiology Sequencing Panel with CNV Detection Panel

Sudden Cardiac Arrest Sequencing Panel with CNV Detection Panel

Comprehensive Cardiac Arrhythmia Sequencing Panel with CNV Detection Panel

Brugada syndrome and related disorders Deletion / Duplication panel Panel

Brugada syndrome and related disorders NGS panel Panel

Cardiac channelopathy Deletion/ Duplication panel Panel

Brugada syndrome and related disorders Comprehensive panel Panel

Cardiac channelopathy Comprehensive panel Panel

Cardiac channelopathy NGS panel Panel

Cardiac conduction abnormalities panel Panel

Brugada syndrome panel Panel

Arrhythmia, familial panel Panel

Brugada syndrome type 2 Panel

Brugada Syndrome Panel Panel

Brugada Syndrome 2 Panel

Cardio-channelopathy-gene-panel Panel

Brugada Syndrome Panel

Arrhythmia Panel

J Wave Syndrome Panel Panel

Inherited Cardiovascular Diseases and Sudden Death Panel Panel

Brugada Syndrome Panel Panel

Ventricular Arrythmia & Sudden Death Panel with Structural Heart Disease Panel

Ventricular Arrythmia & Sudden Death Panel without Structural Heart Disease Panel

Ventricular arrhythmia and sudden death without structural heart disease Panel

Cardiovascular Diseases_General Panel Panel

Brugada syndrome / J wave syndrome Panel

Arrhythmia General Panel Panel

Invitae Arrhythmia Comprehensive Panel Panel

Invitae Arrhythmia and Cardiomyopathy Comprehensive Panel Panel

Invitae Brugada Syndrome Panel Panel

Brugada syndrome type 2: GPD1L gene sequence analysis Panel

BRUGADA SYNDROME Panel

Brugada Syndrome: Sequencing Panel Panel

Arrhythmias: Sequencing Panel Panel

Comprehensive Cardiovascular: Sequencing Panel Panel

Arrhythmias: Deletion/Duplication Panel Panel

Brugada Syndrome: Deletion/Duplication Panel Panel

Comprehensive Cardiovascular: Deletion/Duplication Panel Panel

Familial Arrhythmia Full Gene Sequencing Panel Panel

Arrhythmia NGS Panel Panel

Pan-Cardio NGS Panel Panel