GANAB gene related symptoms and diseases
All the information presented here about the GANAB gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,OMIM,NCBIGENE,ORPHANET, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to GANAB gene
Symptoms // Phenotype | % Cases |
---|---|
Polycystic kidney dysplasia | Very Common - Between 80% and 100% cases |
Dilatation | Very Common - Between 80% and 100% cases |
Dilatation of the cerebral artery | Very Common - Between 80% and 100% cases |
Renal cyst | Very Common - Between 80% and 100% cases |
Abnormality of the kidney | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with GANAB gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Hepatic cysts
- Renal insufficiency
- Hypertension
Not very common - Between 30% and 50% cases
- Cerebral berry aneurysm
- Decreased liver function
- Aortic aneurysm
- Tricuspid regurgitation
- Cerebral hemorrhage
And 34 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to GANAB gene
Here you will find a list of rare diseases related to the GANAB. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
Alternate names
AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE Is also known as apkd1, adpkd, polycystic kidney disease, adult, polycystic kidney disease, adult, type i, potter type iii polycystic kidney disease, formerly
Description
PKD1, an autosomal dominant form of polycystic kidney disease (ADPKD), has the cardinal manifestations of renal cysts, liver cysts, and intracranial aneurysm. Acute and chronic pain and nephrolithiasis are common complications. The most serious renal complication is end-stage renal disease, which occurs in approximately 50% of patients by the age of 60 years. The typical age of onset is in middle life, but the range is from infancy to 80 years (summary by Wu and Somlo, 2000).
Most common symptoms of AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
- Scoliosis
- Pain
- Hypertension
- Talipes equinovarus
- Renal insufficiency
More info about AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
POLYCYSTIC KIDNEY DISEASE 3 WITH OR WITHOUT POLYCYSTIC LIVER DISEASE; PKD3
Alternate names
POLYCYSTIC KIDNEY DISEASE 3 WITH OR WITHOUT POLYCYSTIC LIVER DISEASE; PKD3 Is also known as apkd3, polycystic kidney disease, adult, type iii
Description
Polycystic kidney disease-3, a form of autosomal dominant PKD (ADPKD), is characterized by renal cysts, often associated with liver cysts, that may lead to organ dysfunction. Affected individuals usually present in mid to late adulthood with progressive cysts in the kidney and/or liver. The renal disease is relatively mild, and only some patients develop hypertension; renal insufficiency usually does not occur. The liver disease shows a wide spectrum of severity: some patients have no cysts, whereas others have severe liver involvement (summary by Porath et al., 2016).For a discussion of genetic heterogeneity of PKD, see PKD1 (OMIM ).
Most common symptoms of POLYCYSTIC KIDNEY DISEASE 3 WITH OR WITHOUT POLYCYSTIC LIVER DISEASE; PKD3
- Hypertension
- Renal insufficiency
- Dilatation
- Abnormality of the kidney
- Abnormality of the liver
More info about POLYCYSTIC KIDNEY DISEASE 3 WITH OR WITHOUT POLYCYSTIC LIVER DISEASE; PKD3
SOURCES: OMIM
Search interest in GANAB
Potential gene panels for GANAB gene
Cystic Diseases of the Liver/Kidney Panel by next-generation sequencing (NGS) Panel
By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center Cystic Diseases of the Liver/Kidney Panel by next-generation sequencing (NGS) that also includes the following genes: DNAJB11 SEC63 ALG8 DZIP1L GANAB LRP5 PKD2 PKHD1 PRKCSH
More info about this panelPolycystic kidney and liver disease modifier panel Panel
By Sheffield Diagnostic Genetics Service Sheffield Children's NHS Foundation Trust Polycystic kidney and liver disease modifier panel that also includes the following genes: HNF1B TSC1 TSC2 UMOD DNAJB11 SEC61B SEC61A1 SEC63 ALG8 DZIP1L
More info about this panelPolycystic kidney disease AD (sequence analysis of GANAB gene) Panel
By CGC Genetics
This panel specifically test the GANAB gene.
More info about this panelPolycystic kidney disease AD (sequence analysis of GANAB gene) Panel
By CGC Genetics
This panel specifically test the GANAB gene.
More info about this panelAutosomal Dominant Polycystic Kidney Disease (ADPKD) Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Autosomal Dominant Polycystic Kidney Disease (ADPKD) Sequencing Panel with CNV Detection that also includes the following genes: HNF1B DNAJB11 GANAB PKD1 PKD2
More info about this panelAutosomal Dominant and Recessive Polycystic Kidney Disease (ADPKD and ARPKD) Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Autosomal Dominant and Recessive Polycystic Kidney Disease (ADPKD and ARPKD) Sequencing Panel with CNV Detection that also includes the following genes: HNF1B DNAJB11 DZIP1L GANAB PKD1 PKD2 PKHD1
More info about this panelPolycystic Liver Disease (PLD) Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Polycystic Liver Disease (PLD) Sequencing Panel with CNV Detection that also includes the following genes: SEC63 GANAB LRP5 PKD1 PKD2 PRKCSH
More info about this panelAutosomal Dominant Polycystic Kidney Disease via GANAB Gene Sequencing with CNV Detection Panel
By PreventionGenetics PreventionGenetics
This panel specifically test the GANAB gene.
More info about this panelHereditary Cystic Kidney Diseases Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Hereditary Cystic Kidney Diseases Sequencing Panel with CNV Detection that also includes the following genes: SDCCAG8 HNF1B TSC1 TSC2 UMOD VHL NEK8 DNAJB11 ZNF423 DICER1
More info about this panelPolycystic kidney disease and related disorders NGS panel Panel
By Connective Tissue Gene Tests Polycystic kidney disease and related disorders NGS panel that also includes the following genes: HNF1B TSC1 TSC2 UMOD ALG9 ZNF423 INVS SEC61A1 BICC1 OFD1
More info about this panelPolycystic liver disease Comprehensive panel Panel
By Connective Tissue Gene Tests Polycystic liver disease Comprehensive panel that also includes the following genes: SEC63 GANAB LRP5 PKD1 PKD2 PKHD1 PRKCSH
More info about this panelPolycystic liver disease Deletion / Duplication panel Panel
By Connective Tissue Gene Tests Polycystic liver disease Deletion / Duplication panel that also includes the following genes: SEC63 GANAB LRP5 PKD1 PKD2 PKHD1 PRKCSH
More info about this panelPolycystic kidney disease and related disorders Deletion / Duplication panel Panel
By Connective Tissue Gene Tests Polycystic kidney disease and related disorders Deletion / Duplication panel that also includes the following genes: HNF1B TSC1 TSC2 UMOD ALG9 ZNF423 INVS SEC61A1 BICC1 OFD1
More info about this panelPolycystic liver disease NGS panel Panel
By Connective Tissue Gene Tests Polycystic liver disease NGS panel that also includes the following genes: SEC63 GANAB LRP5 PKD1 PKD2 PKHD1 PRKCSH
More info about this panelPolycystic kidney disease and related disorders Comprehensive panel Panel
By Connective Tissue Gene Tests Polycystic kidney disease and related disorders Comprehensive panel that also includes the following genes: HNF1B TSC1 TSC2 UMOD ALG9 ZNF423 INVS SEC61A1 BICC1 OFD1
More info about this panelPolycystic kidney disease Panel
By Institute of Human Genetics Uniklinik RWTH Aachen Polycystic kidney disease that also includes the following genes: GANAB PKD1 PKD2 PKHD1
More info about this panelHereditary kidney disorders - different panels Panel
By Institute of Human Genetics Uniklinik RWTH Aachen Hereditary kidney disorders - different panels that also includes the following genes: BCS1L ROBO2 CNNM2 CFB SALL1 ATXN10 SCNN1A SCNN1B SCNN1G SDCCAG8
More info about this panelGANAB Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the GANAB gene.
More info about this panelPolycystic Liver Disease Panel Panel
By Blueprint Genetics Polycystic Liver Disease Panel that also includes the following genes: SEC63 GANAB LRP5 PKD1 PKD2 PRKCSH
More info about this panelCystic Kidney Disease Panel Panel
By Blueprint Genetics Cystic Kidney Disease Panel that also includes the following genes: SDCCAG8 SIX5 HNF1B TSC1 TSC2 UMOD VHL NEK8 ZNF423 INVS
More info about this panelPolycystic Kidney Disease Panel Panel
By Blueprint Genetics Polycystic Kidney Disease Panel that also includes the following genes: SEC63 DZIP1L GANAB JAG1 LRP5 NOTCH2 PKD1 PKD2 PKHD1 PRKCSH
More info about this panelPOLYCYSTIC KIDNEY DISEASE (AUTOSOMAL DOMINANT) Panel
By Laboratorio de Genetica Clinica SL POLYCYSTIC KIDNEY DISEASE (AUTOSOMAL DOMINANT) that also includes the following genes: BICC1 GANAB PKD1 PKD2
More info about this panelPOLYCYSTIC KIDNEY DISEASE NGS PANEL Panel
By Laboratorio de Genetica Clinica SL POLYCYSTIC KIDNEY DISEASE NGS PANEL that also includes the following genes: BICC1 DZIP1L GANAB PKD1 PKD2 PKHD1
More info about this panelPolycystic Kidney Disease Panel
By Genome.One Polycystic Kidney Disease that also includes the following genes: HNF1B TSC1 TSC2 UMOD OFD1 GANAB PKD1 PKD2 PKHD1
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