FLG gene related symptoms and diseases

All the information presented here about the FLG gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,HGNC,NCBIGENE, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to FLG gene

Symptoms // Phenotype % Cases
Fever Uncommon - Between 30% and 50% cases
Hyperkeratosis Uncommon - Between 30% and 50% cases
Ichthyosis Uncommon - Between 30% and 50% cases
Asthma Uncommon - Between 30% and 50% cases
Eczema Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with FLG gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Epidermal acanthosis
  • Scaling skin
  • Heat intolerance
  • Allergic rhinitis
  • Eczematoid dermatitis
  • Orthokeratotic hyperkeratosis
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Rare diseases associated to FLG gene

Here you will find a list of rare diseases related to the FLG. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


DERMATITIS, ATOPIC, 2; ATOD2



More info about DERMATITIS, ATOPIC, 2; ATOD2

SOURCES: OMIM MESH

ICHTHYOSIS VULGARIS


Alternate names

ICHTHYOSIS VULGARIS Is also known as ichthyosis simplex

Description

The most common form of ichthyosis. It is an autosomal dominant inherited or acquired disorder characterized by scaling and desquamation of the skin.

Most common symptoms of ICHTHYOSIS VULGARIS

  • Fever
  • Hyperkeratosis
  • Ichthyosis
  • Asthma
  • Eczema


More info about ICHTHYOSIS VULGARIS

SOURCES: OMIM MESH


Potential gene panels for FLG gene

FLG Panel

Germany.

By Institute for Human Genetics University Clinic Freiburg

This panel specifically test the FLG gene.

More info about this panel

FLG (Filaggrin) Hot Spots Panel

United States.

By GeneDx

This panel specifically test the FLG gene.

More info about this panel

FLG. Detection of the mutation p.Arg501X by sequencing Panel

Spain.

By Instituto de Medicina Genomica Instituto de Medicina Genomica

This panel specifically test the FLG gene.

More info about this panel

FLG. Complete sequencing Panel

Spain.

By Instituto de Medicina Genomica Instituto de Medicina Genomica

This panel specifically test the FLG gene.

More info about this panel

Ichthyosis Vulgaris (sequence analysis of FLG gene) Panel

Portugal.

By CGC Genetics

This panel specifically test the FLG gene.

More info about this panel

Ichthyosis Vulgaris (p.Arg501* and p.Ser761Cysfs*36 frequent mutations on FLG gene) Panel

Portugal.

By CGC Genetics

This panel specifically test the FLG gene.

More info about this panel

Ichthyosis Deletion / Duplication panel Panel

United States.

By Connective Tissue Gene Tests Ichthyosis Deletion / Duplication panel that also includes the following genes: ST14 STS SULT2B1 TGM1 TGM5 ALOXE3 ABCA12 CASP14 CHST8 CDSN

More info about this panel

Ichthyosis NGS panel Panel

United States.

By Connective Tissue Gene Tests Ichthyosis NGS panel that also includes the following genes: ST14 STS SULT2B1 TGM1 TGM5 ALOXE3 ABCA12 CASP14 CHST8 CDSN

More info about this panel

Ichthyosis Comprehensive panel Panel

United States.

By Connective Tissue Gene Tests Ichthyosis Comprehensive panel that also includes the following genes: ST14 STS SULT2B1 TGM1 TGM5 ALOXE3 ABCA12 CASP14 CHST8 CDSN

More info about this panel

Ichthyosis vulgaris Panel

Germany.

By Centogene AG - the Rare Disease Company

This panel specifically test the FLG gene.

More info about this panel

Dermatitis, atopic type 2 Panel

Germany.

By Centogene AG - the Rare Disease Company

This panel specifically test the FLG gene.

More info about this panel

Ichthyoses and related disorders of cornification Panel Panel

Germany.

By CeGaT GmbH Ichthyoses and related disorders of cornification Panel that also includes the following genes: SLC27A4 SNAP29 ST14 STS TAT TGM1 TGM5 VPS33B ATP2C1 NSDHL

More info about this panel

Atopic dermatitis / Ichthyosis vulgaris: FLG gene mutation analysis ( p.R501X, c.2282del4) Panel

Spain.

By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases

This panel specifically test the FLG gene.

More info about this panel

FLG Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the FLG gene.

More info about this panel

Ichthyosis Panel Panel

Finland.

By Blueprint Genetics Ichthyosis Panel that also includes the following genes: SLC27A4 STS TGM1 ALOXE3 ABCA12 MBTPS2 SPINK5 MPLKIP CDSN SUMF1

More info about this panel

Ichthyosis vulgaris Panel

Spain.

By Bioarray

This panel specifically test the FLG gene.

More info about this panel

ICHTHYOSIS VULGARIS (SIMPLEX) Panel

Spain.

By Laboratorio de Genetica Clinica SL

This panel specifically test the FLG gene.

More info about this panel

Ichthyosis Vulgaris , Sequencing FLG Gene Panel

Spain.

By Reference Laboratory Genetics

This panel specifically test the FLG gene.

More info about this panel

Ichthyosis Vulgaris, Mutations (p.R501X, c.2282del4) FLG Gene Panel

Spain.

By Reference Laboratory Genetics

This panel specifically test the FLG gene.

More info about this panel

Congenital Ichthyosis and related disorders , Panel Massive Sequencing (NGS) 33 Genes Panel

Spain.

By Reference Laboratory Genetics Congenital Ichthyosis and related disorders , Panel Massive Sequencing (NGS) 33 Genes that also includes the following genes: SLC27A4 SNAP29 ST14 STS TGM1 TGM5 ALOXE3 ABCA12 SPINK5 MPLKIP

More info about this panel

Tempus xT assay Panel

United States.

By Tempus Labs, Inc. Tempus xT assay that also includes the following genes: BCL6 RIT1 BCL7A BCR ROS1 RPL5 RPS15 RPS6KB1 RUNX1 RXRA

More info about this panel

Tempus xO assay Panel

United States.

By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2

More info about this panel


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