FCGR3B gene related symptoms and diseases

All the information presented here about the FCGR3B gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,OMIM,NCBIGENE,ORPHANET, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to FCGR3B gene

Symptoms // Phenotype % Cases
Seizures Common - Between 50% and 80% cases
Arthritis Common - Between 50% and 80% cases
Pericarditis Common - Between 50% and 80% cases
Glomerulonephritis Common - Between 50% and 80% cases
Purpura Common - Between 50% and 80% cases

Other less frequent symptoms and clinical features

Patients with FCGR3B gene alterations may also develop some of the following symptoms and phenotypes:
  • Commonly - More than 50% cases

  • Vasculitis
  • Pleuritis
  • Skin rash
  • Autoimmunity
  • Gangrene
  • Fatigue
  • Not very common - Between 30% and 50% cases

  • Aseptic necrosis
  • Elevated C-reactive protein level

And 118 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to FCGR3B gene

Here you will find a list of rare diseases related to the FCGR3B. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


GRANULOMATOSIS WITH POLYANGIITIS


Alternate names

GRANULOMATOSIS WITH POLYANGIITIS Is also known as wegener granulomatosis, formerly, gpa, wg, formerly

Description

Granulomatosis with polyangiitis is a small-vessel necrotizing vasculitis characterised by the association of inflammation of the vessel wall and peri- and extravascular granulomatosis.

Most common symptoms of GRANULOMATOSIS WITH POLYANGIITIS

  • Seizures
  • Hearing impairment
  • Sensorineural hearing impairment
  • Pain
  • Visual impairment


More info about GRANULOMATOSIS WITH POLYANGIITIS

SOURCES: ORPHANET OMIM MESH

SYSTEMIC LUPUS ERYTHEMATOSUS


Alternate names

SYSTEMIC LUPUS ERYTHEMATOSUS Is also known as disseminated lupus erythematosus, sle

Description

Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by production of autoantibodies against nuclear, cytoplasmic, and cell surface molecules that transcend organ-specific boundaries. Tissue deposition of antibodies or immune complexes induces inflammation and subsequent injury of multiple organs and finally results in clinical manifestations of SLE, including glomerulonephritis, dermatitis, thrombosis, vasculitis, seizures, and arthritis. Evidence strongly suggests the involvement of genetic components in SLE susceptibility (summary by Oishi et al., 2008). Genetic Heterogeneity of Systemic Lupus ErythematosusAn autosomal recessive form of systemic lupus erythematosus (SLEB16 ) is caused by mutation in the DNASE1L3 gene (OMIM ) on chromosome 3p14.3.See MAPPING and MOLECULAR GENETICS sections for a discussion of genetic heterogeneity of susceptibility to SLE.

Most common symptoms of SYSTEMIC LUPUS ERYTHEMATOSUS

  • Seizures
  • Short stature
  • Cognitive impairment
  • Anemia
  • Fatigue


More info about SYSTEMIC LUPUS ERYTHEMATOSUS

SOURCES: OMIM ORPHANET

NEONATAL ALLOIMMUNE NEUTROPENIA



More info about NEONATAL ALLOIMMUNE NEUTROPENIA

SOURCES: ORPHANET


Potential gene panels for FCGR3B gene

Defects of phagocytosis Panel Panel

Germany.

By CeGaT GmbH Defects of phagocytosis Panel that also includes the following genes: STAT1 TAZ TCIRG1 TCN2 TERT WAS WIPF1 ACTB VPS45 HPS3

More info about this panel

Neutrophil Antigen Genotyping Panel (includes HNA-1, 3, 4, 5) Panel

United States.

By BloodCenter of Wisconsin Diagnostic Laboratories BloodCenter of Wisconsin, part of Versiti Neutrophil Antigen Genotyping Panel (includes HNA-1, 3, 4, 5) that also includes the following genes: SLC44A2 CD177 FCGR3B ITGAL ITGAM

More info about this panel

FCGR3B Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the FCGR3B gene.

More info about this panel


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