F12 gene related symptoms and diseases
All the information presented here about the F12 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,NCBIGENE,HGNC,OMIM, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to F12 gene
Symptoms // Phenotype | % Cases |
---|---|
Pain | Very Common - Between 80% and 100% cases |
Abdominal pain | Very Common - Between 80% and 100% cases |
Edema | Very Common - Between 80% and 100% cases |
Retinal vein occlusion | Uncommon - Between 30% and 50% cases |
Pharyngeal edema | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with F12 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Intestinal edema
- Facial edema
- Angioedema
- Upper airway obstruction
- Episodic abdominal pain
- Urticaria
- Vomiting
- Prolonged whole-blood clotting time
And 12 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to F12 gene
Here you will find a list of rare diseases related to the F12. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
CONGENITAL FACTOR XII DEFICIENCY
Alternate names
CONGENITAL FACTOR XII DEFICIENCY Is also known as hageman factor deficiency, f12 deficiency, congenital hageman factor deficiency, haf deficiency
Description
Congenital factor XII deficiency is an autosomal recessive systemic dysfunction of the hemostatic pathway, that is due to a defect in the coagulation factor XII (FXII or Hageman factor), and is either asymptomatic or characterized by a prolonged activated partial thromboplastin time and an increased risk for thromboembolism. FXII deficiency is strongly associated with primary recurrent abortions.
Most common symptoms of CONGENITAL FACTOR XII DEFICIENCY
- Pain
- Edema
- Headache
- Abdominal pain
- Abnormal bleeding
More info about CONGENITAL FACTOR XII DEFICIENCY
HEREDITARY ANGIOEDEMA TYPE 3
Alternate names
HEREDITARY ANGIOEDEMA TYPE 3 Is also known as hae 3, inherited estrogen-dependent angioneurotic edema, inherited estrogen-associated angioedema, inherited estrogen-associated angioneurotic edema, hae iii, hereditary angioedema with normal c1 inhibitor activity, hae-iii, angioneurotic edema, hereditary, with
Description
Hereditary angioedema type 3 (HAE 3) is a form of hereditary angioedema (see this term) characterized by acute edema in subcutaneous tissues, viscera and/or the upper airway.
Most common symptoms of HEREDITARY ANGIOEDEMA TYPE 3
- Pain
- Edema
- Vomiting
- Abdominal pain
- Urticaria
More info about HEREDITARY ANGIOEDEMA TYPE 3
Search interest in F12
Potential gene panels for F12 gene
FXII deficiency Panel
![](/img/flags/Germany.png.pagespeed.ce.gZ_H9lXZoQ.png)
By Institute of Human Genetics Uniklinik RWTH Aachen
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Germany.png.pagespeed.ce.gZ_H9lXZoQ.png)
Hereditary angioedema type 1-3 Panel
![](/img/flags/Germany.png.pagespeed.ce.gZ_H9lXZoQ.png)
By Institute of Human Genetics Uniklinik RWTH Aachen Hereditary angioedema type 1-3 that also includes the following genes: SERPING1 F12
More info about this panel![](/img/flags/Germany.png.pagespeed.ce.gZ_H9lXZoQ.png)
F12 Select Exons Sequencing Panel
![](/img/flags/United-states.png)
By GeneDx
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/United-states.png)
F12 mutation analysis Panel
![](/img/flags/Netherlands.png.pagespeed.ce.VVW97w9GfU.png)
By Laboratory of genome diagnostics Academic Medical Center, University of Amsterdam
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Netherlands.png.pagespeed.ce.VVW97w9GfU.png)
F12. Complete sequencing Panel
![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
F12. Sequencing of the exons 9 Panel
![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
Factor XII deficiency (sequence analysis of F12 gene) Panel
![](/img/flags/Portugal.png.pagespeed.ce.zPu4arfxQG.png)
By CGC Genetics
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Portugal.png.pagespeed.ce.zPu4arfxQG.png)
Hereditary angioedema type 3 (sequence analysis of F12 gene) Panel
![](/img/flags/Portugal.png.pagespeed.ce.zPu4arfxQG.png)
By CGC Genetics
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Portugal.png.pagespeed.ce.zPu4arfxQG.png)
Bleeding Disorders Sequencing Panel with CNV Detection Panel
![](/img/flags/United-states.png)
By PreventionGenetics PreventionGenetics Bleeding Disorders Sequencing Panel with CNV Detection that also includes the following genes: RUNX1 TBXA2R TBXAS1 VWF WAS ADAMTS13 ABCG5 ABCG8 GP6 HPS3
More info about this panel![](/img/flags/United-states.png)
Coagulation Factor Deficiency Sequencing Panel with CNV Detection Panel
![](/img/flags/United-states.png)
By PreventionGenetics PreventionGenetics Coagulation Factor Deficiency Sequencing Panel with CNV Detection that also includes the following genes: VWF MCFD2 VKORC1 F10 F11 F12 F13A1 F13B F2 F5
More info about this panel![](/img/flags/United-states.png)
Factor XII Deficiency Panel
![](/img/flags/Italy.png.pagespeed.ce.ki7TkQ3G4i.png)
By Medical Genetics Laboratory Bambino Gesù Children's Hospital
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Italy.png.pagespeed.ce.ki7TkQ3G4i.png)
Factor XII deficiency Panel
![](/img/flags/Germany.png.pagespeed.ce.gZ_H9lXZoQ.png)
By bio.logis Center for Human Genetics Diagnosticum
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Germany.png.pagespeed.ce.gZ_H9lXZoQ.png)
Single gene testing F12 Panel
![](/img/flags/Germany.png.pagespeed.ce.gZ_H9lXZoQ.png)
By CeGaT GmbH
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Germany.png.pagespeed.ce.gZ_H9lXZoQ.png)
Platelets, Coagulation disorders Panel Panel
![](/img/flags/Germany.png.pagespeed.ce.gZ_H9lXZoQ.png)
By CeGaT GmbH Platelets, Coagulation disorders Panel that also includes the following genes: VHL VWF ADAMTS13 TET2 DSG1 ENTPD1 ETV6 F10 F11 F12
More info about this panel![](/img/flags/Germany.png.pagespeed.ce.gZ_H9lXZoQ.png)
Hereditary Angioedema Type III Panel
![](/img/flags/Germany.png.pagespeed.ce.gZ_H9lXZoQ.png)
By Labor-MVZ Westmecklenburg Laboratory for Molecular Diagnostics
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Germany.png.pagespeed.ce.gZ_H9lXZoQ.png)
Angioedema, hereditary, type III Panel
![](/img/flags/Austria.png.pagespeed.ce.bmb2o24dtJ.png)
By Praxis fuer Humangenetik Wien
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Austria.png.pagespeed.ce.bmb2o24dtJ.png)
Factor 12 deficiency Panel
![](/img/flags/Austria.png.pagespeed.ce.bmb2o24dtJ.png)
By Praxis fuer Humangenetik Wien
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Austria.png.pagespeed.ce.bmb2o24dtJ.png)
Angioedema, hereditary, type III Panel
![](/img/flags/xSlovakia.png.pagespeed.ic.MfIjo-PKfU.png)
By MedGene
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/xSlovakia.png.pagespeed.ic.MfIjo-PKfU.png)
Factor 12 deficiency Panel
![](/img/flags/xSlovakia.png.pagespeed.ic.MfIjo-PKfU.png)
By MedGene
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/xSlovakia.png.pagespeed.ic.MfIjo-PKfU.png)
Angioedema type 3, Hereditary: F12 gene mutation analysis (p.Thr309Lys) Panel
![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
Factor XII deficiency: F12 gene sequence analysis Panel
![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
F12 Panel
![](/img/flags/United-states.png)
By Fulgent Genetics Fulgent Genetics
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/United-states.png)
Bleeding Disorder/Coagulopathy Panel Panel
![](/img/flags/Finland.png.pagespeed.ce.96kqieeVAM.png)
By Blueprint Genetics Bleeding Disorder/Coagulopathy Panel that also includes the following genes: RUNX1 SRC TBXA2R THBD VWF WAS ADAMTS13 ABCG5 ABCG8 HPS3
More info about this panel![](/img/flags/Finland.png.pagespeed.ce.96kqieeVAM.png)
Coagulation Factor Deficiency Panel Panel
![](/img/flags/Finland.png.pagespeed.ce.96kqieeVAM.png)
By Blueprint Genetics Coagulation Factor Deficiency Panel that also includes the following genes: VWF VKORC1 F10 F11 F12 F13A1 F2 F5 F7 F8
More info about this panel![](/img/flags/Finland.png.pagespeed.ce.96kqieeVAM.png)
Comprehensive Hematology Panel Panel
![](/img/flags/Finland.png.pagespeed.ce.96kqieeVAM.png)
By Blueprint Genetics Comprehensive Hematology Panel that also includes the following genes: RHAG RIT1 RPL11 RPL15 RPL35A RPL5 RPS10 RPS19 RPS24 RPS26
More info about this panel![](/img/flags/Finland.png.pagespeed.ce.96kqieeVAM.png)
Genetic Study of Hereditary Thrombophilia (11 genes) Panel
![](/img/flags/Portugal.png.pagespeed.ce.zPu4arfxQG.png)
By HeartGenetics, Genetics and Biotechnology, SA Genetic Study of Hereditary Thrombophilia (11 genes) that also includes the following genes: F12 F13A1 F2 F5 GP1BA MTHFR SERPINC1 SERPINE1 PROCR PROS1
More info about this panel![](/img/flags/Portugal.png.pagespeed.ce.zPu4arfxQG.png)
Hereditary angioedema Panel
![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
By Bioarray
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
Factor XII, deficiency Panel
![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
By Bioarray
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
HEREDITARY ANGIOEDEMA, TYPE 3 Panel
![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
By Laboratorio de Genetica Clinica SL
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
FACTOR XII DEFICIENCY Panel
![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
By Laboratorio de Genetica Clinica SL
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
ATYPICAL HEMOLYTIC UREMIC SYNDROME: NGS PANEL Panel
![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
By Laboratorio de Genetica Clinica SL ATYPICAL HEMOLYTIC UREMIC SYNDROME: NGS PANEL that also includes the following genes: CFB THBD C1S C2 C3 C3AR1 C8A C9 CFHR4 CFHR3
More info about this panel![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
Congenital Factor XII Deficiency , Sequencing F12 Gene Panel
![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
By Reference Laboratory Genetics
This panel specifically test the F12 gene.
More info about this panel![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
Bleeding Disorders , Panel Massive Sequencing (NGS) 23 Genes Panel
![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
By Reference Laboratory Genetics Bleeding Disorders , Panel Massive Sequencing (NGS) 23 Genes that also includes the following genes: VWF ADAMTS13 MCFD2 F10 F11 F12 F13A1 F2 F5 F7
More info about this panel![](/img/flags/Spain.png.pagespeed.ce.xXrgJ_nXfh.png)
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