DLX4 gene related symptoms and diseases
All the information presented here about the DLX4 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,ORPHANET,OMIM,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to DLX4 gene
Symptoms // Phenotype | % Cases |
---|---|
Hypertelorism | Uncommon - Between 30% and 50% cases |
Sparse eyebrow | Uncommon - Between 30% and 50% cases |
Palate fistula | Uncommon - Between 30% and 50% cases |
Agenesis of lateral incisor | Uncommon - Between 30% and 50% cases |
Bilateral cleft palate | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with DLX4 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Euryblepharon
- Ectropion of lower eyelids
- High anterior hairline
- Bilateral cleft lip and palate
- Bilateral cleft lip
- Ectropion
- Sparse eyelashes
- Abnormal facial shape
And 11 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to DLX4 gene
Here you will find a list of rare diseases related to the DLX4. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
OROFACIAL CLEFT 15; OFC15
Most common symptoms of OROFACIAL CLEFT 15; OFC15
- Hypertelorism
- Abnormal facial shape
- Cryptorchidism
- Low-set ears
- Epicanthus
More info about OROFACIAL CLEFT 15; OFC15
SOURCES: OMIM
CLEFT LIP/PALATE
Alternate names
CLEFT LIP/PALATE Is also known as flp, cleft lip-alveolus-palate syndrome, alveolar cleft lip and palate, cleft lip and palate
Description
Cleft lip and palate is a fissure type embryopathy extending across the upper lip, nasal base, alveolar ridge and the hard and soft palate.
More info about CLEFT LIP/PALATE
SOURCES: ORPHANET
Search interest in DLX4
Potential gene panels for DLX4 gene
qGenEx Craniofacial Anomalies Panel
By Quantitative Genomic Medicine Laboratories, SL qGenEx Craniofacial Anomalies that also includes the following genes: RUNX2 SALL1 TSHZ1 BMP4 SEMA3E SF3B4 SH3BP2 SHH SIX1 SIX3
More info about this panelIf you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like ADAMTS17 FIG4 FNDC3B PAM16 TGIF1 KLKB1 ALS2