DLEC1 gene related symptoms and diseases
All the information presented here about the DLEC1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,NCBIGENE,HGNC,ORPHANET, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to DLEC1 gene
Symptoms // Phenotype | % Cases |
---|---|
Cough | Very Common - Between 80% and 100% cases |
Chest pain | Very Common - Between 80% and 100% cases |
Neoplasm | Common - Between 50% and 80% cases |
Abnormality of the voice | Common - Between 50% and 80% cases |
Hemoptysis | Common - Between 50% and 80% cases |
Other less frequent symptoms and clinical features
Patients with DLEC1 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Squamous cell carcinoma
- Lymphadenopathy
- Carcinoma
- Weight loss
Not very common - Between 30% and 50% cases
- Increased body mass index
- Gastroesophageal reflux
- Feeding difficulties in infancy
- Recurrent singultus
And 22 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to DLEC1 gene
Here you will find a list of rare diseases related to the DLEC1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
LUNG CANCER
Description
Lung cancer is the leading cause of cancer deaths in the U.S. and worldwide. The 2 major forms of lung cancer are nonsmall cell lung cancer and small cell lung cancer (see {182280}), which account for 85% and 15% of all lung cancers, respectively. Nonsmall cell lung cancer can be divided into 3 major histologic subtypes: squamous cell carcinoma, adenocarcinoma, and large cell lung cancer. Cigarette smoking causes all types of lung cancer, but it is most strongly linked with small cell lung cancer and squamous cell carcinoma. Adenocarcinoma is the most common type in patients who have never smoked. Nonsmall cell lung cancer is often diagnosed at an advanced stage and has a poor prognosis (summary by Herbst et al., 2008).
Most common symptoms of LUNG CANCER
- Neoplasm
- Pain
- Fatigue
- Respiratory distress
- Diarrhea
More info about LUNG CANCER
SOURCES: OMIM
ESOPHAGEAL CANCER
Description
Esophageal cancer, particularly esophageal squamous cell carcinoma (ESCC), is one of the most common cancers worldwide. Both environmental and genetic risk factors play a role in the pathogenesis of the disorder. In Europe and North America, heavy smoking, alcohol consumption, and increased body mass index (BMI) are the main environmental risk factors. In contrast, the particularly high incidence of ESCC in some areas of China, central Asia, and southern Africa is associated with nutritional deficiencies, high intake of nitrosamine-rich or pickled vegetables, and low socioeconomic status; smoking, alcohol consumption, and BMI play a lesser role in these populations. There is a tendency for familial aggregation of ESCC in high-risk geographic areas, suggesting a genetic component to increased susceptibility. Gastric cardia adenocarcinoma is another common type of cancer in China that shows similarities to ESCC in terms of geographic distribution and environmental risk factors (summary by Wang et al., 2010 and Abnet et al., 2010).
Most common symptoms of ESOPHAGEAL CANCER
- Neoplasm
- Dysphagia
- Obesity
- Weight loss
- Gastroesophageal reflux
More info about ESOPHAGEAL CANCER
SQUAMOUS CELL CARCINOMA OF THE ESOPHAGUS
Alternate names
SQUAMOUS CELL CARCINOMA OF THE ESOPHAGUS Is also known as escc, esophageal epidermoid carcinoma, esophageal squamous cell carcinoma
Description
Esophageal squamous cell carcinoma (ESCC) is a type of esophageal carcinoma (EC; see this term) that can affect any part of the esophagus, but is usually located in the upper or middle third.
Most common symptoms of SQUAMOUS CELL CARCINOMA OF THE ESOPHAGUS
- Feeding difficulties in infancy
- Cough
- Nausea and vomiting
- Lymphadenopathy
- Chest pain
More info about SQUAMOUS CELL CARCINOMA OF THE ESOPHAGUS
SOURCES: ORPHANET
Search interest in DLEC1
Potential gene panels for DLEC1 gene
DLEC1 Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the DLEC1 gene.
More info about this panelIf you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like MCPH1-AS1 HPSE2 PRSS2 EDA2R TGM1 COL4A2 IFNGR1