DCN gene related symptoms and diseases

All the information presented here about the DCN gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,NCBIGENE,OMIM,ORPHANET, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to DCN gene

Symptoms // Phenotype % Cases
Nystagmus Very Common - Between 80% and 100% cases
Strabismus Very Common - Between 80% and 100% cases
Glaucoma Very Common - Between 80% and 100% cases
Photophobia Very Common - Between 80% and 100% cases
Abnormality of the eye Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with DCN gene alterations may also develop some of the following symptoms and phenotypes:
  • Commonly - More than 50% cases

  • Corneal opacity
  • Esotropia
  • Progressive visual loss
  • Exotropia
  • Corneal dystrophy
  • Congenital glaucoma
  • Congenital corneal dystrophy
  • Increased corneal thickness
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Rare diseases associated to DCN gene

Here you will find a list of rare diseases related to the DCN. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


CONGENITAL STROMAL CORNEAL DYSTROPHY


Alternate names

CONGENITAL STROMAL CORNEAL DYSTROPHY Is also known as congenital stromal corneal dystrophy, cscd, witschel dystrophy, congenital hereditary stromal dystrophy

Description

Congenital stromal corneal dystrophy (CSCD) is an extremely rare form of stromal corneal dystrophy (see this term) characterized by opaque flaky or feathery clouding of the corneal stroma, and moderate to severe visual loss.

Most common symptoms of CONGENITAL STROMAL CORNEAL DYSTROPHY

  • Nystagmus
  • Strabismus
  • Glaucoma
  • Photophobia
  • Abnormality of the eye


More info about CONGENITAL STROMAL CORNEAL DYSTROPHY

SOURCES: OMIM MESH ORPHANET


Potential gene panels for DCN gene

DCN Panel

Germany.

By Institute for Human Genetics University Clinic Freiburg

This panel specifically test the DCN gene.

More info about this panel

Corneal Dystrophies Sequencing Panel with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics Corneal Dystrophies Sequencing Panel with CNV Detection that also includes the following genes: TACSTD2 TCF4 ZEB1 TGFBI VSX1 OVOL2 SLC4A11 COL8A2 CYP4V2 ZNF469

More info about this panel

Eye Diseases - panels Panel

Germany.

By MGZ Medical Genetics Center Eye Diseases - panels that also includes the following genes: BFSP1 BFSP2 SALL2 BMP4 BMP7 SHH SIX3 SIX6 FOXL2 SOX2

More info about this panel

Congenital Stromal Corneal Dystrophy Panel

Germany.

By Bioscientia GmbH Center for Human Genetics

This panel specifically test the DCN gene.

More info about this panel

Corneal Dystrophy Panel

Estonia.

By Asper Biogene Asper Biogene LLC Corneal Dystrophy that also includes the following genes: SOD1 TACSTD2 TCF4 ZEB1 TGFBI VSX1 SLC4A11 COL17A1 COL8A2 CYP4V2

More info about this panel

Eye diseases comprehensive panel Panel

Estonia.

By Asper Biogene Asper Biogene LLC Eye diseases comprehensive panel that also includes the following genes: RGS9 RHO GRK1 RLBP1 ROM1 RP1 RP2 RP9 RPE65 RPGR

More info about this panel

DCN Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the DCN gene.

More info about this panel

Corneal Dystrophy Panel Panel

Finland.

By Blueprint Genetics Corneal Dystrophy Panel that also includes the following genes: TACSTD2 TCF4 ZEB1 TGFBI OVOL2 SLC4A11 COL17A1 COL5A1 COL8A2 CYP4V2

More info about this panel

Corneal Dystrophy , Panel Massive Sequencing (NGS) 18 Genes Panel

Spain.

By Reference Laboratory Genetics Corneal Dystrophy , Panel Massive Sequencing (NGS) 18 Genes that also includes the following genes: TACSTD2 TCF4 ZEB1 TGFBI VSX1 SLC4A11 COL5A1 COL8A2 CYP4V2 ZNF469

More info about this panel


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