CYP3A5 gene related symptoms and diseases

All the information presented here about the CYP3A5 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,NCBIGENE,ORPHANET,HGNC, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to CYP3A5 gene

Symptoms // Phenotype % Cases
Hypertension Very Common - Between 80% and 100% cases
Hypertonia Very Common - Between 80% and 100% cases
Small for gestational age Very Common - Between 80% and 100% cases
Hypotension Very Common - Between 80% and 100% cases
Malnutrition Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with CYP3A5 gene alterations may also develop some of the following symptoms and phenotypes:
  • Commonly - More than 50% cases

  • Hyperaldosteronism
  • Pseudohypoaldosteronism
  • Large placenta
  • Elevated systolic blood pressure
  • Elevated diastolic blood pressure
  • Elevated mean arterial pressure
Mendelian

Accelerate your rare disease diagnosis with us

Learn more

Rare diseases associated to CYP3A5 gene

Here you will find a list of rare diseases related to the CYP3A5. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


HYPERTENSION, ESSENTIAL


Alternate names

HYPERTENSION, ESSENTIAL Is also known as eht

Description

The Pickering school held that blood pressure has a continuous distribution, that multiple genes and multiple environmental factors determine the level of one's blood pressure just as the determination of stature and intelligence is multifactorial, and that 'essential hypertension' is merely the upper end of the distribution (Pickering, 1978). In this view the person with essential hypertension is one who happens to inherit an aggregate of genes determining hypertension (and also is exposed to exogenous factors that favor hypertension). The Platt school took the view that essential hypertension is a simple mendelian dominant trait (Platt, 1963). McDonough et al. (1964) defended the monogenic idea. See McKusick (1960) and Kurtz and Spence (1993) for reviews. Swales (1985) reviewed the Platt-Pickering controversy as an 'episode in recent medical history.' The Pickering point of view appears to be more consistent with the observations.

Most common symptoms of HYPERTENSION, ESSENTIAL

  • Hypertension
  • Hypertonia
  • Small for gestational age
  • Hypotension
  • Malnutrition


More info about HYPERTENSION, ESSENTIAL

SOURCES: OMIM


Potential gene panels for CYP3A5 gene

Hypertension, salt-sensitive essential, susceptibility to Panel

Germany.

By Centogene AG - the Rare Disease Company

This panel specifically test the CYP3A5 gene.

More info about this panel

Cytochrome P450 genotyping Panel

Germany.

By bio.logis Center for Human Genetics Diagnosticum Cytochrome P450 genotyping that also includes the following genes: CYP2B6 CYP2C19 CYP2C9 CYP2D6 CYP3A4 CYP3A5

More info about this panel

Pharmacogenetic panel Panel

Germany.

By bio.logis Center for Human Genetics Diagnosticum Pharmacogenetic panel that also includes the following genes: SLC19A1 SLCO1B1 SOD2 TPMT UGT1A1 CCR5 VKORC1 ADH1B CYP2B6 CYP2C19

More info about this panel

Cardiovascular Diseases_General Panel Panel

Spain.

By Health in Code Cardiovascular Diseases_General Panel that also includes the following genes: RIT1 MRPL3 RRAS RYR1 RYR2 SAR1B BLK SCN10A SCN1B SCN2B

More info about this panel

Dyslipidemias / Early atherosclerosis Panel

Spain.

By Health in Code Dyslipidemias / Early atherosclerosis that also includes the following genes: RYR1 SAR1B BLK SLCO1B1 SLC22A8 SLC2A2 HNF1A HNF1B KLF11 WFS1

More info about this panel

Familialhypercholesterolemia Extended Panel Panel

Spain.

By Health in Code Familialhypercholesterolemia Extended Panel that also includes the following genes: RYR1 SLCO1B1 SLC22A8 ABCG5 ABCG8 LDLRAP1 CH25H PCSK9 CPT2 COQ2

More info about this panel

CYP3A5 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the CYP3A5 gene.

More info about this panel

Cytochrome P450 3A5 Panel

United States.

By Molecular Diagnostics Laboratories

This panel specifically test the CYP3A5 gene.

More info about this panel

YouScript Analgesic Panel

United States.

By Genelex YouScript Analgesic that also includes the following genes: CYP2B6 CYP2C9 CYP2D6 CYP3A4 CYP3A5 OPRM1

More info about this panel

YouScript Polypharmacy Panel

United States.

By Genelex YouScript Polypharmacy that also includes the following genes: CYP2C19 CYP2C9 CYP2D6 CYP3A4 CYP3A5

More info about this panel

YouScript Cardio Panel

United States.

By Genelex YouScript Cardio that also includes the following genes: SLCO1B1 VKORC1 CYP2C19 CYP2C9 CYP2D6 CYP3A4 CYP3A5 F2 F5 MTHFR

More info about this panel

YouScript Psychotropic Panel

United States.

By Genelex YouScript Psychotropic that also includes the following genes: SLC6A4 CYP2C19 CYP2C9 CYP2D6 CYP3A4 CYP3A5 HTR2A

More info about this panel

Genecept Assay™ Panel

United States.

By Genomind Genomind, Inc Genecept Assay™ that also includes the following genes: BDNF SLC6A4 CACNA1C CYP2B6 CYP2C19 CYP2C9 CYP2D6 CYP3A5 ADRA2A DRD2

More info about this panel

Comprehensive Pharmacogenomics (PGX) Panel Panel

United States.

By ApolloGen, Inc. Comprehensive Pharmacogenomics (PGX) Panel that also includes the following genes: SLCO1B1 VKORC1 CYP2C19 CYP2C9 CYP2D6 CYP3A4 CYP3A5 F5 HTR2A MTHFR

More info about this panel

Medication Response Genetic Test Panel

United States.

By Color Medication Response Genetic Test that also includes the following genes: SLCO1B1 TPMT IFNL3 NUDT15 VKORC1 CYP2C19 CYP2C9 CYP2D6 CYP3A4 CYP3A5

More info about this panel

OneOme RightMed comprehensive test Panel

United States.

By OneOme OneOme RightMed comprehensive test that also includes the following genes: SLCO1B1 SLC6A4 TPMT UGT1A1 IFNL3 NUDT15 VKORC1 CYP2B6 CYP2C18 CYP2C19

More info about this panel

Rxight Pharmacogenetics Program Panel

United States.

By MD Labs MD Labs Rxight Pharmacogenetics Program that also includes the following genes: SLCO1B1 TPMT UGT2B15 ANKK1 VKORC1 CYP2B6 CYP2C19 CYP2C8 CYP2C9 CYP2D6

More info about this panel

CYP3A5 genotyping Panel

United States.

By Alpha Genomix Laboratories

This panel specifically test the CYP3A5 gene.

More info about this panel

Susceptibility to Drugs , Sequencing CYP3A5 Gene Panel

Spain.

By Reference Laboratory Genetics

This panel specifically test the CYP3A5 gene.

More info about this panel

PharmacoScan Panel

United States.

By RPRD Diagnostics, LLC RPRD Diagnostics, LLC PharmacoScan that also includes the following genes: SLCO1B1 TPMT UGT1A1 VKORC1 CYP2C19 CYP2C9 CYP2D6 CYP3A4 CYP3A5 DPYD

More info about this panel

Pharmacogenomics Tacrolimus Panel

India.

By Foundation for Research In Genetics and Endocrinology and Institute of Human Genetics Institute of Human Genetics

This panel specifically test the CYP3A5 gene.

More info about this panel

Tacrolimus response Panel

India.

By Xcode Life Xcode Life Tacrolimus response that also includes the following genes: CYP3A4 CYP3A5

More info about this panel

Cyclosporine response Panel

India.

By Xcode Life Xcode Life Cyclosporine response that also includes the following genes: CYP3A4 CYP3A5

More info about this panel

Tempus xT assay Panel

United States.

By Tempus Labs, Inc. Tempus xT assay that also includes the following genes: BCL6 RIT1 BCL7A BCR ROS1 RPL5 RPS15 RPS6KB1 RUNX1 RXRA

More info about this panel

Tempus xO assay Panel

United States.

By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2

More info about this panel


If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like MUC4 P3H2 LEFTY2 HOXA1

Need help with a diagnosis?

Learn more about how to achieve it with Mendelian


Learn more