CDK10 gene related symptoms and diseases
All the information presented here about the CDK10 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,OMIM,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to CDK10 gene
Symptoms // Phenotype | % Cases |
---|---|
Intellectual disability | Very Common - Between 80% and 100% cases |
Broad-based gait | Very Common - Between 80% and 100% cases |
Abnormality of the pinna | Very Common - Between 80% and 100% cases |
Abnormal cardiac septum morphology | Very Common - Between 80% and 100% cases |
Synophrys | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with CDK10 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Smooth philtrum
- High, narrow palate
- Small hand
- Triangular face
- Broad nasal tip
- Narrow forehead
- Decreased body weight
- Telecanthus
And 34 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to CDK10 gene
Here you will find a list of rare diseases related to the CDK10. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
AL KAISSI SYNDROME; ALKAS
Alternate names
AL KAISSI SYNDROME; ALKAS Is also known as growth retardation, spine malformation, dysmorphic facies, and developmental delay
Description
Al Kaissi syndrome is an autosomal recessive developmental disorder characterized by growth retardation, spine malformation, particularly of the cervical spine, dysmorphic facial features, and delayed psychomotor development with moderate to severe intellectual disability (summary by Windpassinger et al., 2017).
Most common symptoms of AL KAISSI SYNDROME; ALKAS
- Intellectual disability
- Seizures
- Global developmental delay
- Short stature
- Generalized hypotonia
More info about AL KAISSI SYNDROME; ALKAS
SOURCES: OMIM
Search interest in CDK10
Potential gene panels for CDK10 gene
CDK10 Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the CDK10 gene.
More info about this panelTempus xO assay Panel
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
More info about this panelIf you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like LGI4 LRRK2 ACD CDK6 SMIM1 ZNF335 WARS2