CDK10 gene related symptoms and diseases

All the information presented here about the CDK10 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,OMIM,HGNC, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to CDK10 gene

Symptoms // Phenotype % Cases
Intellectual disability Very Common - Between 80% and 100% cases
Broad-based gait Very Common - Between 80% and 100% cases
Abnormality of the pinna Very Common - Between 80% and 100% cases
Abnormal cardiac septum morphology Very Common - Between 80% and 100% cases
Synophrys Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with CDK10 gene alterations may also develop some of the following symptoms and phenotypes:
  • Commonly - More than 50% cases

  • Smooth philtrum
  • High, narrow palate
  • Small hand
  • Triangular face
  • Broad nasal tip
  • Narrow forehead
  • Decreased body weight
  • Telecanthus

And 34 more phenotypes, you can get all of them using our tools for rare diseases.

Mendelian

Accelerate your rare disease diagnosis with us

Learn more

Rare diseases associated to CDK10 gene

Here you will find a list of rare diseases related to the CDK10. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


AL KAISSI SYNDROME; ALKAS


Alternate names

AL KAISSI SYNDROME; ALKAS Is also known as growth retardation, spine malformation, dysmorphic facies, and developmental delay

Description

Al Kaissi syndrome is an autosomal recessive developmental disorder characterized by growth retardation, spine malformation, particularly of the cervical spine, dysmorphic facial features, and delayed psychomotor development with moderate to severe intellectual disability (summary by Windpassinger et al., 2017).

Most common symptoms of AL KAISSI SYNDROME; ALKAS

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Short stature
  • Generalized hypotonia


More info about AL KAISSI SYNDROME; ALKAS

SOURCES: OMIM


Potential gene panels for CDK10 gene

CDK10 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the CDK10 gene.

More info about this panel

Tempus xO assay Panel

United States.

By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2

More info about this panel


If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like C10orf55 KLLN RHAG SCARB1

Need help with a diagnosis?

Learn more about how to achieve it with Mendelian


Learn more