CD28 gene related symptoms and diseases

All the information presented here about the CD28 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,OMIM,ORPHANET,NCBIGENE, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to CD28 gene

Symptoms // Phenotype % Cases
Hepatomegaly Very Common - Between 80% and 100% cases
Irregular hyperpigmentation Very Common - Between 80% and 100% cases
Edema Very Common - Between 80% and 100% cases
Neoplasm of the skin Very Common - Between 80% and 100% cases
T-cell lymphoma Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with CD28 gene alterations may also develop some of the following symptoms and phenotypes:
  • Commonly - More than 50% cases

  • Abnormal lymphocyte morphology
  • Lymphoma
  • Lymphadenopathy
  • Dry skin
  • Hypotrichosis
  • Pruritus
  • Skin rash
  • Cutaneous T-cell lymphoma

And 32 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to CD28 gene

Here you will find a list of rare diseases related to the CD28. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


CLASSIC MYCOSIS FUNGOIDES


Alternate names

CLASSIC MYCOSIS FUNGOIDES Is also known as mycosis fungoides, alibert-bazin type

Description

Classical mycosis fungoides is the most common type of mycosis fungoides (MF; see this term), a form of cutaneous T-cell lymphoma, and is characterized by slow progression from patches to more infiltrated plaques and eventually to tumors.

Most common symptoms of CLASSIC MYCOSIS FUNGOIDES

  • Hepatomegaly
  • Edema
  • Splenomegaly
  • Alopecia
  • Hyperkeratosis


More info about CLASSIC MYCOSIS FUNGOIDES

SOURCES: MESH ORPHANET OMIM

SÉZARY SYNDROME


Alternate names

SÉZARY SYNDROME Is also known as sÉzary lymphoma

Description

Sézary syndrome (SS) is an aggressive form of cutaneous T-cell lymphoma characterized by a triad of erythroderma, lymphadenopathy and circulating atypical lymphocytes (Sézary cells).

Most common symptoms of SÉZARY SYNDROME

  • Neoplasm
  • Abnormal facial shape
  • Peripheral neuropathy
  • Hepatomegaly
  • Fever


More info about SÉZARY SYNDROME

SOURCES: MESH ORPHANET


Potential gene panels for CD28 gene

CD28 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the CD28 gene.

More info about this panel

Immune Report Card Panel

United States.

By OmniSeq, Inc. Immune Report Card that also includes the following genes: CXCL10 STAT1 TBX21 TGFB1 TNF TNFRSF14 TNFRSF18 CD40 CD27 TNFRSF9

More info about this panel

Tempus xO assay Panel

United States.

By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2

More info about this panel


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