AXIN1 gene related symptoms and diseases

All the information presented here about the AXIN1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,NCBIGENE,OMIM,HGNC, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to AXIN1 gene

Symptoms // Phenotype % Cases
Cryptorchidism Common - Between 50% and 80% cases
Micronodular cirrhosis Uncommon - Between 30% and 50% cases
Hepatic steatosis Uncommon - Between 30% and 50% cases
Hepatitis Uncommon - Between 30% and 50% cases
Type II diabetes mellitus Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with AXIN1 gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Hepatic fibrosis
  • Hepatocellular carcinoma
  • Thrombocytosis
  • Neoplasm of the liver
  • Hypertyrosinemia
  • Hepatoblastoma
  • Abnormality of the liver
  • Chronic hepatitis

And 33 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to AXIN1 gene

Here you will find a list of rare diseases related to the AXIN1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


CAUDAL DUPLICATION


Alternate names

CAUDAL DUPLICATION Is also known as split notochord syndrome, dipygus

Description

Caudal duplication (CD) is a rare developmental anomaly in which structures derived from the embryonic cloaca and notochord are duplicated to varying extents.

Most common symptoms of CAUDAL DUPLICATION

  • Cryptorchidism
  • Omphalocele
  • Abnormality of the genital system
  • Spina bifida
  • Renal hypoplasia/aplasia


More info about CAUDAL DUPLICATION

SOURCES: MESH ORPHANET OMIM

PEDIATRIC HEPATOCELLULAR CARCINOMA


Alternate names

PEDIATRIC HEPATOCELLULAR CARCINOMA Is also known as liver cancer, lcc, childhood-onset hcc, hcc, liver cell carcinoma, hepatoma, cancer, hepatocellular, childhood-onset hepatocellular carcinoma, pediatric hcc

Description

Pediatric hepatocellular carcinoma (pediatric HCC) is a rare, aggressive, malignant hepatic tumor that develops mainly in children over 10 years of age.

Most common symptoms of PEDIATRIC HEPATOCELLULAR CARCINOMA

  • Microcephaly
  • Neoplasm
  • Cryptorchidism
  • Motor delay
  • Hepatomegaly


More info about PEDIATRIC HEPATOCELLULAR CARCINOMA

SOURCES: OMIM ORPHANET

ADULT HEPATOCELLULAR CARCINOMA


Alternate names

ADULT HEPATOCELLULAR CARCINOMA Is also known as adult hcc

Description

Adult hepatocellular carcinoma is the most common primary liver cancer of adulthood. Derived from well-differentiated hepatocytes, it often develops from chronic liver cirrhosis which is most often due to hepatitis B and C virus or alcohol abuse. Symptoms are hepatic mass, abdominal pain and, in advanced stages, jaundice, cachexia and liver failure.


More info about ADULT HEPATOCELLULAR CARCINOMA

SOURCES: ORPHANET


Potential gene panels for AXIN1 gene

Colon Cancer Panel Panel

Germany.

By CeGaT GmbH Colon Cancer Panel that also includes the following genes: BMPR1A STK11 EPCAM TP53 RINT1 FLCN APC SMAD4 MLH1 MSH2

More info about this panel

AXIN1 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the AXIN1 gene.

More info about this panel

FoundationOne® Heme Panel

United States.

By Foundation Medicine, Inc. FoundationOne® Heme that also includes the following genes: BCL6 BCL7A ROS1 RUNX1 BLM SDHA SDHB SDHC SDHD SF3B1

More info about this panel

NeoTYPE® Discovery Profile for Solid Tumors Panel

United States.

By NeoGenomics Laboratories NeoGenomics Laboratories, Inc. NeoTYPE® Discovery Profile for Solid Tumors that also includes the following genes: BCL6 ROS1 RUNX1 BLM SDHA SDHB SDHC SDHD SF3B1 FOXL2

More info about this panel

Caris MI TumorSeek 592-Gene NGS Panel Panel

United States.

By Caris Life Sciences Caris MI TumorSeek 592-Gene NGS Panel that also includes the following genes: BCL6 BCL7A BCL9 BCR ROS1 RPL10 RPL22 RPL5 RPN1 RUNX1

More info about this panel

Providence Personalized Medicine Panel - Solid Tumor Panel

United States.

By Providence Regional Laboratories Providence Health and Services Providence Personalized Medicine Panel - Solid Tumor that also includes the following genes: BCR ROS1 RUNX1 SDHA SDHB SDHC SDHD SF3B1 SRSF2 FOXL2

More info about this panel

Tempus xT assay Panel

United States.

By Tempus Labs, Inc. Tempus xT assay that also includes the following genes: BCL6 RIT1 BCL7A BCR ROS1 RPL5 RPS15 RPS6KB1 RUNX1 RXRA

More info about this panel

Tempus xO assay Panel

United States.

By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2

More info about this panel

PrimBio Colorectal Cancer Panel Panel

United States.

By PrimBio Research Institute PrimBio Research Institute PrimBio Colorectal Cancer Panel that also includes the following genes: BLM BMPR1A SCG5 BRAF BRCA1 STK11 BUB1B EPCAM TCF7L2 TGFBR2

More info about this panel


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