AICDA gene related symptoms and diseases

All the information presented here about the AICDA gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,HGNC,ORPHANET,OMIM, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to AICDA gene

Symptoms // Phenotype % Cases
Immunodeficiency Uncommon - Between 30% and 50% cases
Lymphadenopathy Uncommon - Between 30% and 50% cases
Recurrent bacterial infections Uncommon - Between 30% and 50% cases
IgA deficiency Uncommon - Between 30% and 50% cases
IgG deficiency Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with AICDA gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Recurrent infection of the gastrointestinal tract
  • Impaired Ig class switch recombination
  • Recurrent upper and lower respiratory tract infections
  • Opportunistic infection
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Rare diseases associated to AICDA gene

Here you will find a list of rare diseases related to the AICDA. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


HYPER-IGM SYNDROME TYPE 2


Alternate names

HYPER-IGM SYNDROME TYPE 2 Is also known as activation-induced cytidine deaminase deficiency, aid deficiency, higm2


More info about HYPER-IGM SYNDROME TYPE 2

SOURCES: ORPHANET

IMMUNODEFICIENCY WITH HYPER-IGM, TYPE 2; HIGM2


Alternate names

IMMUNODEFICIENCY WITH HYPER-IGM, TYPE 2; HIGM2 Is also known as hyper-igm syndrome 2

Description

Hyper-IgM syndrome type 2 (HIGM2) is a rare immunodeficiency characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE, resulting in a profound susceptibility to bacterial infections.For a discussion of genetic heterogeneity of immunodeficiency with hyper-IgM, see HIGM1 (OMIM ).

Most common symptoms of IMMUNODEFICIENCY WITH HYPER-IGM, TYPE 2; HIGM2

  • Immunodeficiency
  • Lymphadenopathy
  • Recurrent bacterial infections
  • IgA deficiency
  • IgG deficiency


More info about IMMUNODEFICIENCY WITH HYPER-IGM, TYPE 2; HIGM2

SOURCES: OMIM


Potential gene panels for AICDA gene

Hyper IgM Syndrome (HIGM): (AICDA for HIGM2) (Full Gene Sequencing) Panel

Canada.

By Molecular Diagnostic Laboratory University of Alberta

This panel specifically test the AICDA gene.

More info about this panel

Hyper IgM Syndrome (HIGM): (AICDA for HIGM2) (Known Mutation) Panel

Canada.

By Molecular Diagnostic Laboratory University of Alberta

This panel specifically test the AICDA gene.

More info about this panel

Hyper IgM Syndrome (HIGM): Four-gene Profile (AICDA, UNG, CD40, CD40LG) (Full Gene Sequencing) Panel

Canada.

By Molecular Diagnostic Laboratory University of Alberta Hyper IgM Syndrome (HIGM): Four-gene Profile (AICDA, UNG, CD40, CD40LG) (Full Gene Sequencing) that also includes the following genes: CD40 CD40LG UNG AICDA

More info about this panel

Hyper IgM Syndrome (HIGM): Two-gene Profile (AICDA, UNG) (Full Gene Sequencing) Panel

Canada.

By Molecular Diagnostic Laboratory University of Alberta Hyper IgM Syndrome (HIGM): Two-gene Profile (AICDA, UNG) (Full Gene Sequencing) that also includes the following genes: UNG AICDA

More info about this panel

Hyper IgM Syndrome (HIGM): Three-gene Profile (AICDA, UNG, CD40) (Full Gene Sequencing) Panel

Canada.

By Molecular Diagnostic Laboratory University of Alberta Hyper IgM Syndrome (HIGM): Three-gene Profile (AICDA, UNG, CD40) (Full Gene Sequencing) that also includes the following genes: CD40 UNG AICDA

More info about this panel

Primary Antibody Deficiency Panel, Sequencing and Deletion/Duplication Panel

United States.

By ARUP Laboratories, Molecular Genetics and Genomics Primary Antibody Deficiency Panel, Sequencing and Deletion/Duplication that also includes the following genes: SH2D1A BTK CD40 CD40LG UNG VAV1 AICDA BLNK CD19 CD79A

More info about this panel

AICDA Gene Sequencing Panel

United States.

By GeneDx

This panel specifically test the AICDA gene.

More info about this panel

AICDA. Complete sequencing Panel

Spain.

By Instituto de Medicina Genomica Instituto de Medicina Genomica

This panel specifically test the AICDA gene.

More info about this panel

Humoral dysfunction Del/Dup Panel Panel

United States.

By Division of Genomic Diagnostics The Children's Hospital of Philadelphia Humoral dysfunction Del/Dup Panel that also includes the following genes: SH2D1A BTK STAT1 STAT3 CD27 CD40LG UNG IKZF1 AICDA LRBA

More info about this panel

Humoral dysfunction Seq Analysis Panel

United States.

By Division of Genomic Diagnostics The Children's Hospital of Philadelphia Humoral dysfunction Seq Analysis that also includes the following genes: SH2D1A BTK STAT1 STAT3 CD27 CD40LG UNG IKZF1 AICDA LRBA

More info about this panel

Humoral dysfunction Seq + Del/Dup Panel Panel

United States.

By Division of Genomic Diagnostics The Children's Hospital of Philadelphia Humoral dysfunction Seq + Del/Dup Panel that also includes the following genes: SH2D1A BTK STAT1 STAT3 CD27 CD40LG UNG IKZF1 AICDA LRBA

More info about this panel

Immunodeficiency with hyper-IgM type 2 (sequence analysis of AICDA gene) Panel

Portugal.

By CGC Genetics

This panel specifically test the AICDA gene.

More info about this panel

Immunodeficiency with hyper IgM type 2 Panel

Germany.

By Laboratory for Molecular Diagnostics Center for Nephrology and Metabolic Disorders

This panel specifically test the AICDA gene.

More info about this panel

Hyper IgM Syndrome Sequencing Panel with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics Hyper IgM Syndrome Sequencing Panel with CNV Detection that also includes the following genes: SH2D1A BTK CD40 CD40LG UNG AICDA MRE11 NBN NFKBIA ATM

More info about this panel

Hyper IgM Syndrome via AICDA Gene Sequencing with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics

This panel specifically test the AICDA gene.

More info about this panel

AID gene Panel

United States.

By Immunology Diagnostics Laboratory Seattle Children's Research Institute

This panel specifically test the AICDA gene.

More info about this panel

AICDA Panel

Netherlands.

By Genome Diagnostics Laboratory University Medical Center Utrecht

This panel specifically test the AICDA gene.

More info about this panel

B cell pathology panel Panel

Netherlands.

By Genome Diagnostics Laboratory University Medical Center Utrecht B cell pathology panel that also includes the following genes: BTK CD40 CD40LG UNG AICDA BLNK CD19 CD79A CD79B CD81

More info about this panel

Immunodeficiency type 2, with hyper-IgM Panel

Germany.

By Centogene AG - the Rare Disease Company

This panel specifically test the AICDA gene.

More info about this panel

CentoICU platinum plus Panel

Germany.

By Centogene AG - the Rare Disease Company CentoICU platinum plus that also includes the following genes: RMRP BCS1L BDNF RPS19 RPS6KA3 SALL1 SCN1A SCN2A SFTPB SFTPC

More info about this panel

New Born testing (CentoICU) Panel

Germany.

By Centogene AG - the Rare Disease Company New Born testing (CentoICU) that also includes the following genes: RMRP BCS1L BDNF RPS19 RPS6KA3 SALL1 SCN1A SCN2A SFTPB SFTPC

More info about this panel

Antibody deficiencies Panel Panel

Germany.

By CeGaT GmbH Antibody deficiencies Panel that also includes the following genes: BTK TCF3 TCF4 CD40 TNFSF12 CD40LG UNG AICDA BLNK RTEL1

More info about this panel

Single gene testing AICDA Panel

Germany.

By CeGaT GmbH

This panel specifically test the AICDA gene.

More info about this panel

Invitae Monogenic Autoimmunity Panel Panel

United States.

By Invitae Invitae Monogenic Autoimmunity Panel that also includes the following genes: RMRP SH2D1A SLC7A7 BTK STAT1 STAT3 STAT5B STIM1 STX11 STXBP2

More info about this panel

Invitae Monogenic Inflammatory Bowel Disease Panel Panel

United States.

By Invitae Invitae Monogenic Inflammatory Bowel Disease Panel that also includes the following genes: SH2D1A BTK STAT1 STAT3 STIM1 STXBP2 CD40LG WAS ZAP70 AICDA

More info about this panel

Invitae Primary Immunodeficiency Panel Panel

United States.

By Invitae Invitae Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC SEMA3E SH2D1A SH3BP2 SLC7A7 SMARCAL1 BTK STAT1 STAT2

More info about this panel

Invitae Hyper IgM Syndrome Panel Panel

United States.

By Invitae Invitae Hyper IgM Syndrome Panel that also includes the following genes: CD40LG UNG AICDA

More info about this panel

Early Onset Inflammatory Bowel Disease: Sequencing Panel Panel

United States.

By EGL Genetic Diagnostics Eurofins Clinical Diagnostics Early Onset Inflammatory Bowel Disease: Sequencing Panel that also includes the following genes: SH2D1A BTK STXBP2 CD40LG WAS AICDA HPS4 LRBA DCLRE1C HPS6

More info about this panel

Early Onset Inflammatory Bowel Disease: Deletion/Duplication Panel Panel

United States.

By EGL Genetic Diagnostics Eurofins Clinical Diagnostics Early Onset Inflammatory Bowel Disease: Deletion/Duplication Panel that also includes the following genes: SH2D1A BTK STXBP2 CD40LG WAS AICDA HPS4 LRBA DCLRE1C HPS6

More info about this panel

AICDA Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the AICDA gene.

More info about this panel

Primary Immunodeficiency Panel Panel

Finland.

By Blueprint Genetics Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC CFB BLM SH2D1A SLC7A7 SMARCAL1 SMARCD2 SRP72 BTK

More info about this panel

Immunodeficiency with hyper-IgM, type 2 Panel

Spain.

By Bioarray

This panel specifically test the AICDA gene.

More info about this panel

HYPER-IgM SYNDROME TYPE 2 (AUTOSOMAL RECESSIVE) Panel

Spain.

By Laboratorio de Genetica Clinica SL

This panel specifically test the AICDA gene.

More info about this panel

Hyper IgM Syndrome Type 2 , Sequencing AICDA Gene Panel

Spain.

By Reference Laboratory Genetics

This panel specifically test the AICDA gene.

More info about this panel

Common Variable Immune Deficiency and Related Disorders, Panel Massive Sequencing (NGS) 41 Genes Panel

Spain.

By Reference Laboratory Genetics Common Variable Immune Deficiency and Related Disorders, Panel Massive Sequencing (NGS) 41 Genes that also includes the following genes: CXCL12 SH2D1A BTK STAT1 STAT3 TGFB1 TNFRSF4 CD40 CD40LG AICDA

More info about this panel

Hyper IgM Syndrome ,Panel Massive Sequencing (NGS) 4 Genes Panel

Spain.

By Reference Laboratory Genetics Hyper IgM Syndrome ,Panel Massive Sequencing (NGS) 4 Genes that also includes the following genes: CD40 CD40LG UNG AICDA

More info about this panel


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