ABCG2 gene related symptoms and diseases
All the information presented here about the ABCG2 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,OMIM,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to ABCG2 gene
|Symptoms // Phenotype||% Cases|
|Arthritis||Uncommon - Between 30% and 50% cases|
|Abnormality of the skin||Uncommon - Between 30% and 50% cases|
|Hyperuricemia||Uncommon - Between 30% and 50% cases|
|Gout||Uncommon - Between 30% and 50% cases|
|Anemia||Uncommon - Between 30% and 50% cases|
Other less frequent symptoms and clinical featuresPatients with ABCG2 gene alterations may also develop some of the following symptoms and phenotypes:
Not very common - Between 30% and 50% cases
- Spontaneous abortion
Rare diseases associated to ABCG2 gene
Here you will find a list of rare diseases related to the ABCG2. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
URIC ACID CONCENTRATION, SERUM, QUANTITATIVE TRAIT LOCUS 1; UAQTL1
URIC ACID CONCENTRATION, SERUM, QUANTITATIVE TRAIT LOCUS 1; UAQTL1 Is also known as gout1, gout susceptibility 1
Gout is a common disorder resulting from tissue deposition of monosodium urate crystals as a consequence of hyperuricemia. Patients with gout experience very painful attacks caused by precipitation of urate in joints, which triggers subsequent inflammation. Elevated serum uric acid concentration is a key risk factor for gout (summary from Matsuo et al., 2009 and Woodward et al., 2011).
Most common symptoms of URIC ACID CONCENTRATION, SERUM, QUANTITATIVE TRAIT LOCUS 1; UAQTL1
- Abnormality of the skin
More info about URIC ACID CONCENTRATION, SERUM, QUANTITATIVE TRAIT LOCUS 1; UAQTL1
BLOOD GROUP, JUNIOR SYSTEM; JR
Individuals with Jr(a-) blood group lack the Jr(a) antigen on their red blood cells. These individuals may have anti-Jr(a) antibodies in their serum, which can cause transfusion reactions or hemolytic disease of the fetus or newborn. Although the clinical significance of the Jr(a-) blood group has been controversial, severe fatal hemolytic disease of the newborn has been reported. The Jr(a-) phenotype has a higher frequency in individuals of Asian descent, compared to those of European descent (summary by Kim et al., 2010 and Zelinski et al., 2012).
Most common symptoms of BLOOD GROUP, JUNIOR SYSTEM; JR
- Spontaneous abortion
More info about BLOOD GROUP, JUNIOR SYSTEM; JR
Search interest in ABCG2
Potential gene panels for ABCG2 gene
By Fulgent Genetics Fulgent Genetics
This panel specifically test the ABCG2 gene.More info about this panel
Tempus xO assay Panel
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2More info about this panel