Familial Papillary Or Follicular Thyroid Carcinoma

Table of contents:

Description
Related genes
Clinical Features
Incidence and onset information
Alternative Names
Researches and researchers
Gene Panels
Sources and references

Description

Familial papillary or follicular thyroid carcinoma is a rare, hereditary nonmedullary thyroid carcinoma characterized by the presence of differentiated thyroid cancer of follicular cell origin in two or more first-degree relatives, in the absence of other familial tumor syndromes or radiation exposure. Frequent capsular invasion is observed. Biopsy reveals multicentric tumors with multiple adenomatous nodules with or without oxyphilia and follicular or papillary carcinoma histology.

Genes related to Familial Papillary Or Follicular Thyroid Carcinoma

FOXE1
MINPP1
HABP2

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Clinical Features

Top most frequent phenotypes and symptoms related to Familial Papillary Or Follicular Thyroid Carcinoma

Pain
Recurrent fractures
Bone pain
Goiter
Colon cancer
Spinal cord compression
Chronic lung disease
Chronic noninfectious lymphadenopathy
Papillary thyroid carcinoma
Abnormality of the lymph nodes

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Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.

Alternative names

Familial Papillary Or Follicular Thyroid Carcinoma Is also known as fnmtc, familial pure nonmedullary thyroid carcinoma.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Familial Papillary Or Follicular Thyroid Carcinoma Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Congenital Hypothyroidism Deletion/Duplication Panel. By Genetic Services Laboratory University of Chicago (United States). SLC16A2, SLC5A5, TG, THRA, THRB, NKX2-1, TPO, TSHB, KDM6A, DUOX2, UBR1, IYD, GLIS3, DUOXA2, FOXE1, IGSF1, KMT2D, PAX8, SLC26A4, POU1F1 , (...) View the complete list with 1 more genes Panel complete gene list SLC16A2, SLC5A5, TG, THRA, THRB, NKX2-1, TPO, TSHB, KDM6A, DUOX2, UBR1, IYD, GLIS3, DUOXA2, FOXE1, IGSF1, KMT2D, PAX8, SLC26A4, POU1F1, PROP1 Specificity 5 % Genes 34 %
Congenital Hypothyroidism Sequencing Panel. By Genetic Services Laboratory University of Chicago (United States). SLC16A2, SLC5A5, TG, THRA, THRB, NKX2-1, TPO, TSHB, KDM6A, DUOX2, UBR1, IYD, GLIS3, DUOXA2, FOXE1, IGSF1, KMT2D, PAX8, SLC26A4, POU1F1 , (...) View the complete list with 1 more genes Panel complete gene list SLC16A2, SLC5A5, TG, THRA, THRB, NKX2-1, TPO, TSHB, KDM6A, DUOX2, UBR1, IYD, GLIS3, DUOXA2, FOXE1, IGSF1, KMT2D, PAX8, SLC26A4, POU1F1, PROP1 Specificity 5 % Genes 34 %
FOXE1 mutation analysis. By Laboratory of genome diagnostics Academic Medical Center, University of Amsterdam (Netherlands). FOXE1 Specificity 100 % Genes 34 %
Congenital Hypothyroidism and Thyroid Hormone Resistance Sequencing Panel with CNV Detection. By PreventionGenetics PreventionGenetics (United States). SLC16A2, SLC5A5, TG, THRA, THRB, NKX2-1, TPO, TRH, TSHB, DUOX2, UBR1, IYD, NKX2-5, GLIS3, SECISBP2, DUOXA2, FOXE1, GNAS, HESX1, IGSF1 , (...) View the complete list with 4 more genes Panel complete gene list SLC16A2, SLC5A5, TG, THRA, THRB, NKX2-1, TPO, TRH, TSHB, DUOX2, UBR1, IYD, NKX2-5, GLIS3, SECISBP2, DUOXA2, FOXE1, GNAS, HESX1, IGSF1, PAX8, SLC26A4, POU1F1, PROP1 Specificity 5 % Genes 34 %
Bamforth-Lazarus Syndrome via FOXE1 Gene Sequencing with CNV Detection. By PreventionGenetics PreventionGenetics (United States). FOXE1 Specificity 100 % Genes 34 %
Cleft lip, cleft palate and related disorders NGS panel. By Connective Tissue Gene Tests (United States). BMP4, TBX22, SUMO1, TP63, TGDS, SATB2, COL11A1, COL11A2, COL9A1, COL9A2, COL9A3, GRHL3, FOXE1, IRF6, MSX1, NECTIN1 Specificity 7 % Genes 34 %
Cleft lip, cleft palate and related disorders Deletion / Duplication panel. By Connective Tissue Gene Tests (United States). BMP4, TBX22, SUMO1, TP63, TGDS, SATB2, COL11A1, COL11A2, COL9A1, COL9A2, COL9A3, GRHL3, FOXE1, IRF6, MSX1, NECTIN1 Specificity 7 % Genes 34 %
Cleft lip, cleft palate and related disorders Comprehensive panel. By Connective Tissue Gene Tests (United States). BMP4, TBX22, SUMO1, TP63, TGDS, SATB2, COL11A1, COL11A2, COL9A1, COL9A2, COL9A3, GRHL3, FOXE1, IRF6, MSX1, NECTIN1 Specificity 7 % Genes 34 %

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Sources and references

You can check the following sources for additional information.

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