Hypodontia-dysplasia Of Nails Syndrome

Description

Hypodontia-nail dysplasia syndrome is a form of ectodermal dysplasia.

Clinical Features

Top most frequent phenotypes and symptoms related to Hypodontia-dysplasia Of Nails Syndrome

  • Abnormality of the dentition
  • Sparse hair
  • Everted lower lip vermilion
  • Delayed eruption of teeth
  • Hypodontia
  • Ectodermal dysplasia
  • Small nail
  • Fine hair
  • Abnormality of the nail
  • Abnormality of the fingernails

And another 14 symptoms. If you need more information about this disease we can help you.

Click here to know more about Mendelian.

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
No data available about the known clinical features onset.

Alternative names

Hypodontia-dysplasia Of Nails Syndrome Is also known as hypodontia-nail dysgenesis syndrome, tns, witkop syndrome, ectd3, ectodermal dysplasia 3, witkop type, nail dysplasia with hypodontia, tooth-and-nail syndrome, tooth and nail syndrome, ectodermal dysplasia 3, tooth/nail type.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Hypodontia-dysplasia Of Nails Syndrome Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Orofacial cleft 5 (sequence analysis of MSX1 gene).

By CGC Genetics (Portugal).

MSX1
Specificity
100 %
Genes
100 %
Ectodermal dysplasia (NGS panel for 8 genes).

By CGC Genetics (Portugal).

EDARADD, KRT74, EDAR, EDA, GJB6, HOXC13, KRT85, MSX1
Specificity
13 %
Genes
100 %
Ectodermal dysplasia (NGS panel for 8 genes).

By CGC Genetics (Portugal).

EDARADD, KRT74, EDAR, EDA, GJB6, HOXC13, KRT85, MSX1
Specificity
13 %
Genes
100 %
Ectodermal Dysplasia/Tooth Agenesis via MSX1 Gene Sequencing with CNV Detection.

By PreventionGenetics PreventionGenetics (United States).

MSX1
Specificity
100 %
Genes
100 %
Tooth Agenesis Sequencing Panel with CNV Detection.

By PreventionGenetics PreventionGenetics (United States).

WNT10A, EDARADD, EDAR, EDA, LTBP3, MSX1, PAX9, AXIN2
Specificity
13 %
Genes
100 %
Cleft lip, cleft palate and related disorders NGS panel.

By Connective Tissue Gene Tests (United States).

BMP4, TBX22, SUMO1, TP63, TGDS, SATB2, COL11A1, COL11A2, COL9A1, COL9A2, COL9A3, GRHL3, FOXE1, IRF6, MSX1, NECTIN1
Specificity
7 %
Genes
100 %
Cleft lip, cleft palate and related disorders Deletion / Duplication panel.

By Connective Tissue Gene Tests (United States).

BMP4, TBX22, SUMO1, TP63, TGDS, SATB2, COL11A1, COL11A2, COL9A1, COL9A2, COL9A3, GRHL3, FOXE1, IRF6, MSX1, NECTIN1
Specificity
7 %
Genes
100 %
Cleft lip, cleft palate and related disorders Comprehensive panel.

By Connective Tissue Gene Tests (United States).

BMP4, TBX22, SUMO1, TP63, TGDS, SATB2, COL11A1, COL11A2, COL9A1, COL9A2, COL9A3, GRHL3, FOXE1, IRF6, MSX1, NECTIN1
Specificity
7 %
Genes
100 %

You can get up to 34 more panels with our dedicated tool

Learn more

Sources and references

You can check the following sources for additional information.

MESH OMIM ORPHANET Rare Disease Symptoms Checker

If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like MYOCLONIC-ATONIC EPILEPSY; MAE