Well-differentiated Liposarcoma

Description

Well-differentiated liposarcoma (WDLS), the most common type of liposarcoma (LS; see this term), is a slow growing, painless tumor usually located in the retroperitoneum or the limbs. It is composed of proliferating mature adipocytes.

Clinical Features

Phenotypes and symptoms related to Well-differentiated Liposarcoma

  • Subcutaneous nodule
  • Gastrointestinal dysmotility
  • Abnormal renal physiology

Incidence and onset information

— Based on the latest data available Well-differentiated Liposarcoma have a estimated incidence of 0.51 per 100k worldwide.
No data available about the known clinical features onset.

Alternative names

Well-differentiated Liposarcoma Is also known as alt, atypical lipoma, wdls, atypical lipomatous tumor.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.


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Well-differentiated Liposarcoma Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Liposarcoma, well differentiated (sequence analysis of MDM2 gene).

By CGC Genetics (Portugal).

MDM2
Specificity
100 %
Genes
34 %
Cancer Hotspot Panel.

By Centogene AG - the Rare Disease Company (Germany).

BCL6, ROS1, BRAF, BRCA1, BRCA2, SMARCB1, SMO, SRC, STK11, HNF1A, TP53, TSC1, TSC2, VHL, EML4, BRD4, CCND1, CCNE1, FBXW7, CD74 , (...)

View the complete list with 68 more genes
Specificity
3 %
Genes
67 %
MDM2.

By Fulgent Genetics Fulgent Genetics (United States).

MDM2
Specificity
100 %
Genes
34 %
COLOTRUE™.

By Pathway Genomics (United States).

BMPR1A, STK11, EPCAM, TP53, CDH1, APC, SMAD4, MDM2, MLH1, MSH2, MSH6, MUTYH, PMS2, PTEN
Specificity
8 %
Genes
34 %
FoundationOne® Heme.

By Foundation Medicine, Inc. (United States).

BCL6, BCL7A, ROS1, RUNX1, BLM, SDHA, SDHB, SDHC, SDHD, SF3B1, SRSF2, SGK1, FOXL2, BRAF, BRCA1, BRCA2, SMARCA1, SMARCA4, SMARCB1, ARID1A , (...)

View the complete list with 374 more genes
Specificity
1 %
Genes
67 %
NeoTYPE® Discovery Profile for Solid Tumors.

By NeoGenomics Laboratories NeoGenomics Laboratories, Inc. (United States).

BCL6, ROS1, RUNX1, BLM, SDHA, SDHB, SDHC, SDHD, SF3B1, FOXL2, BRAF, BRCA1, BRCA2, SLIT2, SMARCA4, SMARCB1, ARID1A, KDM5C, SMO, SNCAIP , (...)

View the complete list with 288 more genes
Specificity
1 %
Genes
67 %
Caris MI TumorSeek 592-Gene NGS Panel.

By Caris Life Sciences (United States).

BCL6, BCL7A, BCL9, BCR, ROS1, RPL10, RPL22, RPL5, RPN1, RUNX1, BLM, SDC4, SDHB, SDHC, SDHD, BMPR1A, SET, SF3B1, SFPQ, SRSF2 , (...)

View the complete list with 559 more genes
Specificity
1 %
Genes
100 %
OmniSeq Comprehensive.

By OmniSeq, Inc. (United States).

RHEB, BCL9, ROS1, RPS6KB1, SF3B1, FOXL2, BRAF, BRCA1, BRCA2, SMARCB1, SMO, SOX2, SPOP, SRC, BTK, STAT3, STK11, HNF1A, TERT, TIAF1 , (...)

View the complete list with 122 more genes
Specificity
2 %
Genes
67 %

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Sources and references

You can check the following sources for additional information.

ORPHANET Genetic Syndrome Finder

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