Takayasu Arteritis

Description

Takayasu arteritis (TAK) is a rare inflammatory large-vessel vasculitis primarily affecting the aorta and its major branches, but also other large vessels, causing stenosis, occlusion, or aneurysm.

Clinical Features

Top most frequent phenotypes and symptoms related to Takayasu Arteritis

  • Seizures
  • Muscle weakness
  • Anemia
  • Hypertension
  • Fever
  • Fatigue
  • Dilatation
  • Hyperhidrosis
  • Weight loss
  • Arthralgia

And another 31 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Based on the latest data available TAKAYASU ARTERITIS have a estimated incidence of 0.19 per 100k worldwide.
No data available about the known clinical features onset.

Alternative names

Takayasu Arteritis Is also known as young female arteritis, aortic arch syndrome, pulseless disease.

Researches and researchers

Doctors, researchs, and experts related to Takayasu Arteritis extracted from public data.

Takayasu Arteritis Experts map



Current Researchs and researchers

  • PARIS — Pr Loïc GUILLEVIN

    Coordinator of expert centre - Clinical expert - Principal investigator of clinical trial - Manager of registry - Contact person of registry - Coordinator of research network

    • Institution/s:
      — CHU Paris Centre - Hôpital Cochin, Site Cochin
    • Research area/topic::

      GFEV: French study group on vasculitis - research organization on necrotising angeitis, systemic diseases and vaccinale research


  • LÜBECK — Pr Wolfgang L. GROSS

    Investigator of research project - Manager of registry

    • Institution/s:
      — Universitätsklinikum Schleswig-Holstein - Campus Lübeck
    • Research area/topic::

      DCVAS: American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) - Study to develop new diagnostic and classification criteria for Primary Systemic Vasculitis


  • BARCELONA — Dr María Cinta CID XUTGLA

    Principal investigator of clinical trial - Investigator of research project

    • Institution/s:
      — Hospital Clínic de Barcelona
    • Research area/topic::

      ACR/EULAR: endorsed study to develop new diagnostic and classification criteria for primary systemic vasculitis


  • CAMBRIDGE — Dr David JAYNE

    Coordinator of expert centre - Principal investigator of clinical trial - Investigator of clinical trial - Coordinator of research network

    • Institution/s:
      — Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital
    • Research area/topic::

      EUVAS: European vasculitis study group


  • CAMBRIDGE — Dr James PETERS

    Investigator of research project

    • Institution/s:
      — University of Cambridge
    • Research area/topic::

      An integrated genetic and proteomic approach to understanding cardiovascular disease aetiology


Takayasu Arteritis Recommended genes panels

Panel Name, Specifity and genes Tested/covered
IL12B Sequencing.

By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center (United States).

IL12B
Specificity
100 %
Genes
34 %
Familial Atypical Mycobacteriosis (sequence analysis of IL12B gene).

By CGC Genetics (Portugal).

IL12B
Specificity
100 %
Genes
34 %
Psoriasis susceptibility type 11.

By Centogene AG - the Rare Disease Company (Germany).

IL12B
Specificity
100 %
Genes
34 %
Defects of phagocytosis Panel.

By CeGaT GmbH (Germany).

STAT1, TAZ, TCIRG1, TCN2, TERT, WAS, WIPF1, ACTB, VPS45, HPS3, HPS4, HAX1, HPS5, DTNBP1, CEBPE, HPS6, SBDS, SLC35C1, BLOC1S3, VPS13B , (...)

View the complete list with 39 more genes
Specificity
2 %
Genes
34 %
Invitae Mendelian Susceptibility to Mycobacterial Disease Panel.

By Invitae (United States).

STAT1, STAT2, ACP5, TYK2, SAMHD1, IRAK4, ADAR, CYBB, ISG15, GATA2, IRF8, IFNGR1, IFNGR2, IL12B, IL12RB1, MYD88
Specificity
7 %
Genes
34 %
Invitae Primary Immunodeficiency Panel.

By Invitae (United States).

RMRP, RORC, SEMA3E, SH2D1A, SH3BP2, SLC7A7, SMARCAL1, BTK, STAT1, STAT2, STAT3, STAT5B, STIM1, STK4, STX11, STXBP2, TAPBP, TAZ, TBK1, TCN2 , (...)

View the complete list with 187 more genes
Specificity
1 %
Genes
34 %
IL12B.

By Fulgent Genetics Fulgent Genetics (United States).

IL12B
Specificity
100 %
Genes
34 %
Primary Immunodeficiency Panel.

By Blueprint Genetics (Finland).

RMRP, RORC, CFB, BLM, SH2D1A, SLC7A7, SMARCAL1, SMARCD2, SRP72, BTK, STAT1, STAT2, STAT3, STAT5B, STIM1, STK4, STX11, STXBP2, TAPBP, TBX1 , (...)

View the complete list with 253 more genes
Specificity
1 %
Genes
34 %

You can get up to 0 more panels with our dedicated tool

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Sources and references

You can check the following sources for additional information.

ORPHANET OMIM Rare Disease Symptoms Checker

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