Systemic Mastocytosis With An Associated Clonal Hematologic Non-mast Cell Lineage Disease

Description

Systemic mastocytosis with an associated clonal hematological non-mast cell lineage disease is a form of systemic mastocytosis (SM) associated with malignancy (other than mast cell leukemia).

Clinical Features

Phenotypes and symptoms related to Systemic Mastocytosis With An Associated Clonal Hematologic Non-mast Cell Lineage Disease

  • Eosinophilia
  • Myelodysplasia
  • Acute myeloid leukemia
  • Chronic myelogenous leukemia
  • Non-Hodgkin lymphoma
  • Mastocytosis
  • Chronic myelomonocytic leukemia

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
No data available about the known clinical features onset.

Alternative names

Systemic Mastocytosis With An Associated Clonal Hematologic Non-mast Cell Lineage Disease Is also known as systemic mastocytosis with associated hematologic neoplasm, sm-ahnmd, sm-ahn.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.


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Systemic Mastocytosis With An Associated Clonal Hematologic Non-mast Cell Lineage Disease Recommended genes panels

Panel Name, Specifity and genes Tested/covered
KIT related disorders - KIT Sequencing.

By Children's Hospital Colorado Molecular Genetics Laboratory Children's Hospital Colorado (United States).

KIT
Specificity
100 %
Genes
100 %
KIT Mutation Analysis.

By Molecular Genetics Diagnostic Laboratory Detroit Medical Center University Laboratories (United States).

KIT
Specificity
100 %
Genes
100 %
MyeloidDx by NGS.

By Molecular Genetics Diagnostic Laboratory Detroit Medical Center University Laboratories (United States).

RUNX1, SF3B1, SRSF2, BRAF, SMC1A, STAG2, TP53, U2AF1, KDM6A, WT1, IKZF1, CALR, CBL, CBLB, SETBP1, FBXW7, CDKN2A, PHF6, ASXL1, CEBPA , (...)

View the complete list with 32 more genes
Specificity
2 %
Genes
100 %
MyeloidDx by NGS.

By Molecular Genetics Diagnostic Laboratory Detroit Medical Center University Laboratories (United States).

RUNX1, SF3B1, SRSF2, BRAF, SMC1A, STAG2, TP53, U2AF1, KDM6A, WT1, IKZF1, CALR, CBL, CBLB, SETBP1, CBLC, FBXW7, CDKN2A, PHF6, CEBPA , (...)

View the complete list with 31 more genes
Specificity
2 %
Genes
100 %
Hereditary Gastric Cancer Panel.

By Genetic Services Laboratory University of Chicago (United States).

SDHB, SDHC, BMPR1A, BRCA1, BRCA2, STK11, EPCAM, TP53, CDH1, CTNNA1, APC, KIT, SMAD4, MLH1, MSH2, MSH6, PDGFRA, PMS2, PTEN
Specificity
6 %
Genes
100 %
KIT. Complete sequencing.

By Instituto de Medicina Genomica Instituto de Medicina Genomica (Spain).

KIT
Specificity
100 %
Genes
100 %
Hereditary Colorectal and Gastrointestinal Cancer Panel.

By Division of Genomic Diagnostics The Children's Hospital of Philadelphia (United States).

BMPR1A, BRCA1, BRCA2, STK11, EPCAM, TP53, CDH1, CDK4, CDKN2A, PALB2, APC, KIT, SMAD4, MLH1, MSH2, MSH6, MUTYH, ATM, PMS2, POLD1 , (...)

View the complete list with 2 more genes
Specificity
5 %
Genes
100 %
CHOP Comprehensive Hereditary Cancer Panel.

By Division of Genomic Diagnostics The Children's Hospital of Philadelphia (United States).

RMRP, RUNX1, BLM, SDHA, SDHB, SDHC, SDHD, BMPR1A, SH2D1A, SLC25A13, BRCA1, BRCA2, SMARCA4, SMARCB1, SMARCE1, BUB1B, EPCAM, XPA, IKZF1, CBL , (...)

View the complete list with 85 more genes
Specificity
1 %
Genes
100 %

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Sources and references

You can check the following sources for additional information.

ORPHANET Genetic Syndrome Finder

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