Specific Language Impairment 1; Sli1

Description

Specific language impairment (SLI) is a common developmental disorder characterized by difficulty in language acquisition despite otherwise normal development and in the absence of any obvious explanatory factors (summary by Newbury et al., 2009). Genetic Heterogeneity of Specific Language ImpairmentMultiple loci for specific language impairment have been mapped, including SLI1 on chromosome 16q; SLI2 (OMIM ) on chromosome 19q; SLI3 (OMIM ) on chromosome 13q21; SLI4 (OMIM ) on chromosome 7q35-36; and SLI5 (OMIM ), caused by mutation in the TM4SF20 gene (OMIM ) on chromosome 2q36.

Clinical Features

Phenotypes and symptoms related to Specific Language Impairment 1; Sli1

  • Delayed speech and language development
  • Language impairment
  • Deficit in phonologic short-term memory
  • Deficit in nonword repetition

Incidence and onset information

Not enough data available about incidence and published cases.
No data available about the known clinical features onset.

Alternative names

Specific Language Impairment 1; Sli1 Is also known as specific language impairment quantitative trait locus on chromosome 16.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.


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Sources and references

You can check the following sources for additional information.

OMIM Rare Disease Search Engine

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