Rheumatoid Arthritis, Systemic Juvenile

Description

Systemic-onset juvenile idiopathic arthritis is marked by the severity of the extra-articular manifestations (fever, cutaneous eruptions) and by an equal sex ratio.

Clinical Features

Top most frequent phenotypes and symptoms related to Rheumatoid Arthritis, Systemic Juvenile

  • Pica
  • Visual impairment
  • Hepatomegaly
  • Splenomegaly
  • Fever
  • Visual loss
  • Abdominal pain
  • Arthritis
  • Arthralgia
  • Hepatosplenomegaly
And another 15 symptoms. If you need more information about this disease we can help you.
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Incidence and onset information

— Based on the latest data available Rheumatoid Arthritis, Systemic Juvenile have a estimated prevalence of 5 per 100k worldwide.


Mendelian

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Rheumatoid Arthritis, Systemic Juvenile Recommended genes panels

Panel Name, Specifity and genes Tested/covered
MIF.

By Fulgent Genetics Fulgent Genetics in United States.

MIF
Specificity
100 %
Genes
25 %
LACC1.

By Fulgent Genetics Fulgent Genetics in United States.

LACC1
Specificity
100 %
Genes
25 %
Narcolepsy Risk Factor.

By Bioscientia GmbH Center for Human Genetics in Germany.

HLA-DQB1, HLA-DRB1
Specificity
50 %
Genes
25 %
HLA-DRB1.

By Fulgent Genetics Fulgent Genetics in United States.

HLA-DRB1
Specificity
100 %
Genes
25 %
Tempus xT assay.

By Tempus Labs, Inc. in United States.

BRCA1, BRCA2, MTHFR, VHL, APC, EPCAM, MSH2, PMS2, MSH6, MLH1, MUTYH, PTEN, RECQL4, RUNX1, TP53, ATP7B, FOXL2, HNF1A, WT1, RB1 , (...)

View the complete list with 571 more genes
Specificity
1 %
Genes
25 %
Crohn Disease.

By Bioscientia GmbH Center for Human Genetics in Germany.

NOD2, IL6
Specificity
50 %
Genes
25 %
IL6.

By Fulgent Genetics Fulgent Genetics in United States.

IL6
Specificity
100 %
Genes
25 %
OmniSeq Comprehensive.

By OmniSeq, Inc. in United States.

BRCA1, BRCA2, VHL, APC, MSH2, MLH1, PTEN, TP53, FOXL2, HNF1A, PPARG, WT1, RB1, RET, RAF1, IDH2, SOX2, STAT3, PNP, FGFR3 , (...)

View the complete list with 124 more genes
Specificity
1 %
Genes
25 %
Inflammatory Bowel Disease (IBD) and Related Disorders , Panel Massive Sequencing (NGS) 46 Genes.

By Reference Laboratory Genetics in Spain.

TGFB1, CYBA, IL2RG, IKBKG, TINF2, CYBB, WAS, GATA3, FOXP1, FOXP3, DKC1, ABCB1, TERC, TERT, SH2D1A, NCF2, NCF4, WRAP53, NOD2, CD40LG , (...)

View the complete list with 25 more genes
Specificity
3 %
Genes
25 %

Alternate names

Rheumatoid Arthritis, Systemic Juvenile Is also known as systemic juvenile rheumatoid arthritis;still disease; systemic polyarthritis; systemic-onset jia.


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