Pyloric Stenosis, Infantile Hypertrophic, 1; Ihps1

Description

Infantile pyloric stenosis is the most common condition requiring surgical intervention in the first year of life. It typically presents in infants 2 to 6 weeks after birth. Clinically the disorder is characterized by projectile vomiting, visible gastric peristalsis, and a palpable pyloric tumor (summary by Everett et al., 2008). Mortality was high until successful treatment by pyloromyotomy was developed by Ramstedt (1912). Genetic Heterogeneity of Infantile Hypertrophic Pyloric StenosisMultiple susceptibility loci have been implicated in IHPS including IHPS1 on chromosome 12q, IHPS2 (OMIM ) on chromosome 16p13-p12, IHPS3 (OMIM ) on chromosome 11q14-q22, IHPS4 (OMIM ) on chromosome Xq23, and IHPS5 (OMIM ) on chromosome 16q24.

Clinical Features

Phenotypes and symptoms related to Pyloric Stenosis, Infantile Hypertrophic, 1; Ihps1

  • Neoplasm
  • Failure to thrive
  • Vomiting
  • Pyloric stenosis
  • Projectile vomiting
  • Hypochloremic metabolic alkalosis

Incidence and onset information

Not enough data available about incidence and published cases.
No data available about the known clinical features onset.

Alternative names

Pyloric Stenosis, Infantile Hypertrophic, 1; Ihps1 Is also known as pyloric stenosis, infantile hypertrophic, pyloric stenosis, infantile, ihps.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.


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Sources and references

You can check the following sources for additional information.

OMIM Genetic Syndrome Finder

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