Peeling Skin Syndrome 5; Pss5

Description

Peeling skin syndrome-5 (PSS5) is characterized by superficial peeling of the dorsal and palmar skin of the hands and feet; the skin of the forearms and legs may also be involved. Some patients exhibit diffuse yellowish hyperkeratotic palmoplantar plaques (Pigors et al., 2016).For a general phenotypic description and a discussion of genetic heterogeneity of peeling skin syndrome, see PSS1 (OMIM ).

Clinical Features

Phenotypes and symptoms related to Peeling Skin Syndrome 5; Pss5

  • Hyperkeratosis
  • Erythema
  • Ichthyosis
  • Epidermal acanthosis
  • Scaling skin
  • Psoriasiform dermatitis

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
No data available about the known clinical features onset.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Peeling Skin Syndrome 5; Pss5 Recommended genes panels

Panel Name, Specifity and genes Tested/covered
SERPINB8.

By Institute for Human Genetics University Clinic Freiburg (Germany).

SERPINB8
Specificity
100 %
Genes
100 %
Epidermolysis bullosa Comprehensive panel.

By Connective Tissue Gene Tests (United States).

DST, TGM5, FERMT1, CHST8, CDSN, COL17A1, COL7A1, CSTA, KLHL24, DSP, EXPH5, ITGA3, ITGA6, ITGB4, JUP, KRT14, KRT5, LAMA3, LAMB3, LAMC2 , (...)

View the complete list with 3 more genes
Specificity
5 %
Genes
100 %
Ichthyosis Deletion / Duplication panel.

By Connective Tissue Gene Tests (United States).

ST14, STS, SULT2B1, TGM1, TGM5, ALOXE3, ABCA12, CASP14, CHST8, CDSN, POMP, PNPLA1, LIPN, CERS3, CSTA, CYP4F22, NIPAL4, FLG, KDSR, GJA1 , (...)

View the complete list with 7 more genes
Specificity
4 %
Genes
100 %
Epidermolysis bullosa NGS panel.

By Connective Tissue Gene Tests (United States).

DST, TGM5, FERMT1, CHST8, CDSN, COL17A1, COL7A1, CSTA, KLHL24, DSP, EXPH5, ITGA3, ITGA6, ITGB4, JUP, KRT14, KRT5, LAMA3, LAMB3, LAMC2 , (...)

View the complete list with 3 more genes
Specificity
5 %
Genes
100 %
Ichthyosis NGS panel.

By Connective Tissue Gene Tests (United States).

ST14, STS, SULT2B1, TGM1, TGM5, ALOXE3, ABCA12, CASP14, CHST8, CDSN, POMP, PNPLA1, LIPN, CERS3, CSTA, CYP4F22, NIPAL4, FLG, KDSR, GJA1 , (...)

View the complete list with 7 more genes
Specificity
4 %
Genes
100 %
Epidermolysis bullosa Deletion / Duplication panel.

By Connective Tissue Gene Tests (United States).

DST, TGM5, FERMT1, CHST8, CDSN, COL17A1, COL7A1, CSTA, KLHL24, DSP, EXPH5, ITGA3, ITGA6, ITGB4, JUP, KRT14, KRT5, LAMA3, LAMB3, LAMC2 , (...)

View the complete list with 3 more genes
Specificity
5 %
Genes
100 %
Ichthyosis Comprehensive panel.

By Connective Tissue Gene Tests (United States).

ST14, STS, SULT2B1, TGM1, TGM5, ALOXE3, ABCA12, CASP14, CHST8, CDSN, POMP, PNPLA1, LIPN, CERS3, CSTA, CYP4F22, NIPAL4, FLG, KDSR, GJA1 , (...)

View the complete list with 7 more genes
Specificity
4 %
Genes
100 %
Peeling skin syndrome NGS panel.

By Connective Tissue Gene Tests (United States).

TGM5, CAST, CHST8, CDSN, CSTA, FLG2, SERPINB8
Specificity
15 %
Genes
100 %

You can get up to 3 more panels with our dedicated tool

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Sources and references

You can check the following sources for additional information.

OMIM Rare Disease Search Engine

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