Palmoplantar Keratoderma, Nagashima Type

Description

Keratosis, Nagashima-type is a transgressive and nonprogressive palmoplantar keratoderma resembling a mild form of mal de Meleda (see this term).

Clinical Features

Top most frequent phenotypes and symptoms related to Palmoplantar Keratoderma, Nagashima Type

  • Flexion contracture
  • Hyperhidrosis
  • Hyperkeratosis
  • Erythema
  • Palmoplantar keratoderma
  • Epidermal acanthosis
  • Palmoplantar hyperkeratosis
  • Parakeratosis
  • Hypergranulosis
  • Orthokeratosis

And another 3 symptoms. If you need more information about this disease we can help you.

Click here to know more about Mendelian.

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
No data available about the known clinical features onset.

Alternative names

Palmoplantar Keratoderma, Nagashima Type Is also known as ppk, nagashima type, palmoplantar hyperkeratosis, nagashima type.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Palmoplantar Keratoderma, Nagashima Type Recommended genes panels

Panel Name, Specifity and genes Tested/covered
SERPINB7.

By Institute for Human Genetics University Clinic Freiburg (Germany).

SERPINB7
Specificity
100 %
Genes
100 %
Ichthyoses and related disorders of cornification Panel.

By CeGaT GmbH (Germany).

SLC27A4, SNAP29, ST14, STS, TAT, TGM1, TGM5, VPS33B, ATP2C1, NSDHL, ALOXE3, WNT10A, SERPINB7, ELOVL4, ABCA12, MBTPS2, SPINK5, CARD14, CDSN, TRPV3 , (...)

View the complete list with 44 more genes
Specificity
2 %
Genes
100 %
SERPINB7.

By Fulgent Genetics Fulgent Genetics (United States).

SERPINB7
Specificity
100 %
Genes
100 %
Palmoplantar Keratoderma Panel.

By Blueprint Genetics (Finland).

WNT10A, SERPINB7, MBTPS2, TRPV3, SLURP1, KRT6C, CTSC, AAGAB, DSG1, DSP, ENPP1, GJB2, GJB4, GJB6, JUP, AQP5, KRT1, KRT14, KRT16, KRT17 , (...)

View the complete list with 5 more genes
Specificity
4 %
Genes
100 %

You can get up to -4 more panels with our dedicated tool

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Sources and references

You can check the following sources for additional information.

ORPHANET OMIM Rare Disease Search Engine

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