Ovarian Hyperstimulation Syndrome

Description

A complication of OVULATION INDUCTION in infertility treatment. It is graded by the severity of symptoms which include OVARY enlargement, multiple OVARIAN FOLLICLES; OVARIAN CYSTS; ASCITES; and generalized EDEMA. The full-blown syndrome may lead to RENAL FAILURE, respiratory distress, and even DEATH. Increased capillary permeability is caused by the vasoactive substances, such as VASCULAR ENDOTHELIAL GROWTH FACTORS, secreted by the overly-stimulated OVARIES.

Clinical Features

Top most frequent phenotypes and symptoms related to Ovarian Hyperstimulation Syndrome

  • Abdominal pain
  • Nausea and vomiting
  • Infertility
  • Nausea
  • Hirsutism
  • Ascites
  • Abdominal distention
  • Aspiration
  • Abnormality of the genitourinary system
  • Pleural effusion

And another 10 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
No data available about the known clinical features onset.

Alternative names

Ovarian Hyperstimulation Syndrome Is also known as ovarian hyperstimulation syndrome, familial gestational spontaneous, ohss.

Researches and researchers

Doctors, researchs, and experts related to Ovarian Hyperstimulation Syndrome extracted from public data.

Ovarian Hyperstimulation Syndrome Experts map



Current Researchs and researchers

  • ILLKIRCH-GRAFFENSTADEN — Pr Stéphane VIVILLE

    Investigator of research project

    • Institution/s:
      — IGBMC - CNRS UMR 7104 - Inserm U 1258, Institut de génétique et de biologie moléculaire et cellulaire - IGBMC
    • Research area/topic::

      Exome sequencing in a consanguineous family with spontaneous ovarian hyperstimulation cases with unknown triggers



Mendelian

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Ovarian Hyperstimulation Syndrome Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Premature Ovarian Failure Sequencing Panel.

By Genetic Services Laboratory University of Chicago (United States).

BMP15, FOXL2, MCM8, PSMC3IP, HFM1, NOBOX, FIGLA, FSHR, LMNA, NR5A1
Specificity
10 %
Genes
100 %
Premature Ovarian Failure Deletion/Duplication Panel.

By Genetic Services Laboratory University of Chicago (United States).

BMP15, FOXL2, MCM8, PSMC3IP, HFM1, NOBOX, FIGLA, FSHR, LMNA, NR5A1
Specificity
10 %
Genes
100 %
FSHR. Complete sequencing.

By Instituto de Medicina Genomica Instituto de Medicina Genomica (Spain).

FSHR
Specificity
100 %
Genes
100 %
46,XX gonadal dysgenesis (sequence analysis of FSHR gene).

By CGC Genetics (Portugal).

FSHR
Specificity
100 %
Genes
100 %
46,XX gonadal dysgenesis (FSH receptor polymorphisms).

By CGC Genetics (Portugal).

FSHR
Specificity
100 %
Genes
100 %
Ovarian Dysgenesis 1.

By Laboratory of Genetics BioTe21 Adam Master (Poland).

FSHR
Specificity
100 %
Genes
100 %
Ovarian Dysgenesis and Ovarian Hyperstimulation Syndrome via FSHR Gene Sequencing with CNV Detection.

By PreventionGenetics PreventionGenetics (United States).

FSHR
Specificity
100 %
Genes
100 %
Female Infertility Sequencing Panel with CNV Detection.

By PreventionGenetics PreventionGenetics (United States).

BMP15, SEMA3A, SEMA3E, FOXL2, SOX10, SOX2, SOX3, SOX9, SRA1, SRD5A2, SRY, STAG3, STAR, TAC3, TACR3, WNT4, WT1, WWOX, ZP1, ARL6 , (...)

View the complete list with 84 more genes
Specificity
1 %
Genes
100 %

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Sources and references

You can check the following sources for additional information.

ORPHANET MESH OMIM Rare Disease Search Engine

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