Osteoarthritis Susceptibility 2; Os2
Description
In the hand, osteoarthritis can develop in the distal interphalangeal and the first carpometacarpal (base of thumb) and proximal interphalangeal joints (Stefansson et al., 2003). Patients with osteoarthritis may have one, a few, or all of these sites affected. Heberden nodes are bony excrescences of the phalanges of the distal interphalangeal joints of the fingers (Stecher, 1955). They can be considered a variety of osteoarthrosis, or degenerative arthritis.For a phenotypic description and a discussion of genetic heterogeneity of osteoarthritis, see OS1 (OMIM ).
Clinical Features
Phenotypes and symptoms related to Osteoarthritis Susceptibility 2; Os2
- Arthritis
- Osteoarthritis
- Heberden's node
Incidence and onset information
— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)— No data available about the known clinical features onset.
Alternative names
Osteoarthritis Susceptibility 2; Os2 Is also known as dipoa, hoa, hand osteoarthritis, oadip, osteoarthritis of distal interphalangeal joints.
Researches and researchers
Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.Osteoarthritis Susceptibility 2; Os2 Recommended genes panels
Panel Name, Specifity and genes Tested/covered |
---|
MATN3. Sequencing of the exon 2.
By Instituto de Medicina Genomica Instituto de Medicina Genomica (Spain).
MATN3
Specificity
100 %
Genes
100 % |
MATN3. Complete sequencing.
By Instituto de Medicina Genomica Instituto de Medicina Genomica (Spain).
MATN3
Specificity
100 %
Genes
100 % |
Epiphyseal dysplasia multiple (NGS panel for 7 gene).
By CGC Genetics (Portugal).
SLC26A2, COL9A1, COL9A2, COL9A3, COMP, MATN3
Specificity
17 %
Genes
100 % |
Multiple Epiphyseal Dysplasia via MATN3 Gene Sequencing with CNV Detection.
By PreventionGenetics PreventionGenetics (United States).
MATN3
Specificity
100 %
Genes
100 % |
Multiple Epiphyseal Dysplasia Sequencing Panel.
By PreventionGenetics PreventionGenetics (United States).
SLC26A2, COL9A1, COL9A2, COL9A3, COMP, MATN3
Specificity
17 %
Genes
100 % |
Skeletal Disorders and Joint Problems Sequencing Panel with CNV Detection.
By PreventionGenetics PreventionGenetics (United States).
RMRP, ROR2, RUNX2, SALL1, BMP1, BMP2, BMPR1B, SF3B4, SH3BP2, FBXW4, SHH, SHOX, SKI, SLCO2A1, SLC26A2, SMARCAL1, SMC1A, SOX9, SQSTM1, TBX15 , (...)
View the complete list with 236 more genes
Specificity
1 %
Genes
100 % |
Multiple epiphyseal dysplasia (MED) Deletion / Duplication panel.
By Connective Tissue Gene Tests (United States).
SLC26A2, CANT1, COL9A1, COL9A2, COL9A3, COMP, MATN3
Specificity
15 %
Genes
100 % |
Multiple epiphyseal dysplasia (MED) NGS panel.
By Connective Tissue Gene Tests (United States).
SLC26A2, CANT1, COL9A1, COL9A2, COL9A3, COMP, MATN3
Specificity
15 %
Genes
100 % |
You can get up to 33 more panels with our dedicated tool
Learn moreSources and references
You can check the following sources for additional information.
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