Orofacial Cleft 5; Ofc5

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.

Alternative names

Orofacial Cleft 5; Ofc5 Is also known as cleft lip with or without cleft palate, nonsyndromic, 5.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Orofacial Cleft 5; Ofc5 Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Orofacial cleft 5 (sequence analysis of MSX1 gene). By CGC Genetics (Portugal). MSX1 Specificity 100 % Genes 100 %
Ectodermal dysplasia (NGS panel for 8 genes). By CGC Genetics (Portugal). EDARADD, KRT74, EDAR, EDA, GJB6, HOXC13, KRT85, MSX1 Specificity 13 % Genes 100 %
Ectodermal dysplasia (NGS panel for 8 genes). By CGC Genetics (Portugal). EDARADD, KRT74, EDAR, EDA, GJB6, HOXC13, KRT85, MSX1 Specificity 13 % Genes 100 %
Ectodermal Dysplasia/Tooth Agenesis via MSX1 Gene Sequencing with CNV Detection. By PreventionGenetics PreventionGenetics (United States). MSX1 Specificity 100 % Genes 100 %
Tooth Agenesis Sequencing Panel with CNV Detection. By PreventionGenetics PreventionGenetics (United States). WNT10A, EDARADD, EDAR, EDA, LTBP3, MSX1, PAX9, AXIN2 Specificity 13 % Genes 100 %
Cleft lip, cleft palate and related disorders NGS panel. By Connective Tissue Gene Tests (United States). BMP4, TBX22, SUMO1, TP63, TGDS, SATB2, COL11A1, COL11A2, COL9A1, COL9A2, COL9A3, GRHL3, FOXE1, IRF6, MSX1, NECTIN1 Specificity 7 % Genes 100 %
Cleft lip, cleft palate and related disorders Deletion / Duplication panel. By Connective Tissue Gene Tests (United States). BMP4, TBX22, SUMO1, TP63, TGDS, SATB2, COL11A1, COL11A2, COL9A1, COL9A2, COL9A3, GRHL3, FOXE1, IRF6, MSX1, NECTIN1 Specificity 7 % Genes 100 %
Cleft lip, cleft palate and related disorders Comprehensive panel. By Connective Tissue Gene Tests (United States). BMP4, TBX22, SUMO1, TP63, TGDS, SATB2, COL11A1, COL11A2, COL9A1, COL9A2, COL9A3, GRHL3, FOXE1, IRF6, MSX1, NECTIN1 Specificity 7 % Genes 100 %

Sources and references

You can check the following sources for additional information.

OMIM MESH Rare Disease Symptoms Checker

If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like SEIZURES, BENIGN FAMILIAL INFANTILE, 3; BFIS3 EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 14; EIEE14 EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 54; EIEE54 EHLERS-DANLOS SYNDROME, PROGEROID TYPE, 2; EDSP2 MITOCHONDRIAL DNA DEPLETION SYNDROME 11; MTDPS11 THIAMINE METABOLISM DYSFUNCTION SYNDROME 4 (BILATERAL STRIATAL DEGENERATION AND PROGRESSIVE POLYNEUROPATHY TYPE); THMD4 MEDULLARY CYSTIC KIDNEY DISEASE 1; MCKD1