Odonto-onycho-dermal Dysplasia

Description

Odonto-onycho-dermal dysplasia is a form of ectodermal dysplasia characterised by hyperkeratosis and hyperhidrosis of the palms and soles, atrophic malar patches, hypodontia, conical teeth, onychodysplasia, and dry and sparse hair.

Clinical Features

Top most frequent phenotypes and symptoms related to Odonto-onycho-dermal Dysplasia

  • Intellectual disability
  • Hyperhidrosis
  • Photophobia
  • Erythema
  • Sparse hair
  • Nail dystrophy
  • Hypotrichosis
  • Dry skin
  • Hypodontia
  • Ectodermal dysplasia

And another 30 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
No data available about the known clinical features onset.

Alternative names

Odonto-onycho-dermal Dysplasia Is also known as oodd.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.


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Odonto-onycho-dermal Dysplasia Recommended genes panels

Panel Name, Specifity and genes Tested/covered
WNT10A.

By Institute for Human Genetics University Clinic Freiburg (Germany).

WNT10A
Specificity
100 %
Genes
100 %
WNT10A Gene Sequencing.

By GeneDx (United States).

WNT10A
Specificity
100 %
Genes
100 %
TP63,EDA,EDAR,EDARADD,WNT10A, NextGeneDx.Complete sequencing by NGS.

By Instituto de Medicina Genomica Instituto de Medicina Genomica (Spain).

WNT10A, EDARADD, TP63, EDAR, EDA
Specificity
20 %
Genes
100 %
WNT10A. Complete sequencing.

By Instituto de Medicina Genomica Instituto de Medicina Genomica (Spain).

WNT10A
Specificity
100 %
Genes
100 %
Odontoonychodermal dysplasia (sequence analysis of WNT10A gene).

By CGC Genetics (Portugal).

WNT10A
Specificity
100 %
Genes
100 %
Ectodermal dysplasia 1, hypohidrotic, X-linked (deletion/duplication analysis of genes EDA, EDAR, EDARADD and WNT10A).

By CGC Genetics (Portugal).

WNT10A, EDARADD, EDAR, EDA
Specificity
25 %
Genes
100 %
Ectodermal Dysplasia Sequencing Panel with CNV Detection.

By PreventionGenetics PreventionGenetics (United States).

WNT10A, EDARADD, EDAR, EDA, KRT85, NECTIN1
Specificity
17 %
Genes
100 %
Ectodermal Dysplasia via WNT10A Gene Sequencing with CNV Detection.

By PreventionGenetics PreventionGenetics (United States).

WNT10A
Specificity
100 %
Genes
100 %

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Sources and references

You can check the following sources for additional information.

ORPHANET MESH OMIM Rare Disease Search Engine

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