Nail Disorder, Nonsyndromic Congenital, 1; Ndnc1
Many types of nonsyndromic congenital nail disorders (NDNC) have been described. Twenty-nail dystrophy (TND), also known as trachyonychia (from the Greek for 'rough nails'), is an autosomal dominant nail dystrophy characterized by excessive longitudinal striations and numerous superficial pits on the nails, which have a distinctive rough sandpaper-like appearance. Occasionally some nails are spared. The slowly progressive condition is usually apparent at birth and may be self-limiting, with spontaneous resolution in some patients (summary by Sehgal, 2007). TND is referred to here as nonsyndromic congenital nail disorder-1 (NCNC1).
Clinical FeaturesPhenotypes and symptoms related to Nail Disorder, Nonsyndromic Congenital, 1; Ndnc1
- Nail dystrophy
- Nail dysplasia
- Thick nail
- Thin nail
- Alopecia areata
Incidence and onset information— Not enough data available about incidence and published cases.
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Nail Disorder, Nonsyndromic Congenital, 1; Ndnc1 Is also known as twenty-nail dystrophy, onychodystrophy totalis, isolated;.
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