Muir-torre Syndrome

Table of contents:

Description
Related genes
Clinical Features
Incidence and onset information
Alternative Names
Researches and researchers
Gene Panels
Sources and references

Description

Muir-Torre syndrome (MTS) is a form of hereditary nonpolyposis colon cancer (HNPCC) characterized by cutaneous sebaceous tumors, keratoacanthomas and at least one visceral malignancy, most frequently gastrointestinal carcinoma.

Genes related to Muir-torre Syndrome

MSH6
MLH1
MSH2

View recommended genes panels

Clinical Features

Top most frequent phenotypes and symptoms related to Muir-torre Syndrome

Neoplasm
Carcinoma
Leukemia
Nevus
Lymphoma
Vasculitis
Hyperlipidemia
Neoplasm of the skin
Breast carcinoma
Basal cell carcinoma

And another 21 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.

Alternative names

Muir-torre Syndrome Is also known as cutaneous sebaceous neoplasms and keratoacanthomas, multiple, with gastrointestinal and other carcinomas, multiple keratoacanthoma, muir-torre type.

Researches and researchers

Doctors, researchs, and experts related to Muir-torre Syndrome extracted from public data.

Muir-torre Syndrome Experts map

Current Researchs and researchers

HALLE (SAALE) — Pr Wolfgang G. BALLHAUSEN
Responsible for diagnostic tests - Investigator of research project
- Institution/s:
  — Medizinische Fakultät der Martin-Luther-Universität Halle-Wittenberg
- Research area/topic::
  The function of fragile histidine triad gene (FHIT) gene in Muir-Torre syndrome and other tumors

Muir-torre Syndrome Recommended genes panels

Panel Name, Specifity and genes Tested/covered
HNPCC MSI & IHC Screening. By Baylor Miraca Genetics Laboratories (United States). EPCAM, MLH1, MSH2, MSH6, PMS2 Specificity 60 % Genes 100 %
MSH6 Comprehensive - Sequence & Deletion/Duplication Analysis. By Baylor Miraca Genetics Laboratories (United States). MSH6 Specificity 100 % Genes 34 %
MSH6 Deletion/Duplication Analysis. By Baylor Miraca Genetics Laboratories (United States). MSH6 Specificity 100 % Genes 34 %
MSH6 Sequence Analysis. By Baylor Miraca Genetics Laboratories (United States). MSH6 Specificity 100 % Genes 34 %
MSH6 Sequence Analysis (Familial Mutation/Variant Analysis). By Baylor Miraca Genetics Laboratories (United States). MSH6 Specificity 100 % Genes 34 %
Mismatch Repair Proteins Immunohistochemistry. By Baylor Miraca Genetics Laboratories (United States). MLH1, MSH2, MSH6, PMS2 Specificity 75 % Genes 100 %
Hereditary Brain, CNS, PNS Cancer Panel. By Baylor Miraca Genetics Laboratories (United States). TP53, VHL, SUFU, PALB2, ALK, APC, MEN1, MLH1, MRE11, MSH2, MSH6, NBN, NF2, ATM, PMS2, PHOX2B, PTCH1 Specificity 18 % Genes 100 %
Hereditary Brain, CNS, PNS Cancer Panel. By Baylor Miraca Genetics Laboratories (United States). TP53, VHL, SUFU, PALB2, ALK, APC, MEN1, MLH1, MRE11, MSH2, MSH6, NBN, NF2, ATM, PMS2, PHOX2B, PTCH1 Specificity 18 % Genes 100 %

You can get up to 470 more panels with our dedicated tool

Sources and references

You can check the following sources for additional information.

MESH ORPHANET OMIM Rare Disease Search Engine

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