Mirror Movements 1; Mrmv1

Description

Mirror movements are contralateral involuntary movements that mirror voluntary ones. Whereas mirror movements are occasionally found in normal young children, persistence beyond the age of 10 years is abnormal. Congenital mirror movements tend to persist throughout adulthood and tend to occur more commonly in the upper extremities (summary by Sharafaddinzadeh et al., 2008 and Srour et al., 2010). Some patients with DCC mutations have agenesis of the corpus callosum (Marsh et al., 2017). Genetic Heterogeneity of Mirror MovementsSee also MRMV2 (OMIM ), caused by mutation in the RAD51 gene (OMIM ) on chromosome 15q15, and MRMV3 (OMIM ), caused by mutation in the DNAL4 gene (OMIM ) on chromosome 22q13.

Clinical Features

Phenotypes and symptoms related to Mirror Movements 1; Mrmv1

  • Pain
  • Delayed speech and language development
  • Intellectual disability, mild
  • Agenesis of corpus callosum
  • Abnormality of the nervous system
  • Clumsiness
  • Involuntary movements
  • Partial agenesis of the corpus callosum
  • Bimanual synkinesia

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
No data available about the known clinical features onset.

Alternative names

Mirror Movements 1; Mrmv1 Is also known as mirror movements 1 and/or agenesis of the corpus callosum, bimanual synergia, mirror movements, congenital.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.


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Mirror Movements 1; Mrmv1 Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Congenital mirror movements type 1 (deletion/duplication analysis of DCC gene).

By CGC Genetics (Portugal).

DCC
Specificity
100 %
Genes
100 %
Congenital mirror movements type 1 (sequence analysis of DCC gene).

By CGC Genetics (Portugal).

DCC
Specificity
100 %
Genes
100 %
Congenital mirror movements type 1 (deletion/duplication analysis of DCC gene).

By CGC Genetics (Portugal).

DCC
Specificity
100 %
Genes
100 %
Congenital mirror movements type 1 (sequence analysis of DCC gene).

By CGC Genetics (Portugal).

DCC
Specificity
100 %
Genes
100 %
Mirror movements type 1.

By Centogene AG - the Rare Disease Company (Germany).

DCC
Specificity
100 %
Genes
100 %
Esophageal carcinoma, somatic.

By Centogene AG - the Rare Disease Company (Germany).

DCC
Specificity
100 %
Genes
100 %
Colorectal cancer, somatic.

By Centogene AG - the Rare Disease Company (Germany).

DCC
Specificity
100 %
Genes
100 %
Single gene testing DCC.

By CeGaT GmbH (Germany).

DCC
Specificity
100 %
Genes
100 %

We have 5 more panels available in our App

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Sources and references

You can check the following sources for additional information.

OMIM Rare Disease Symptoms Checker

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