Meier-gorlin Syndrome 2; Mgors2

Clinical Features

Top most frequent phenotypes and symptoms related to Meier-gorlin Syndrome 2; Mgors2

  • Microcephaly
  • Growth delay
  • Failure to thrive
  • Micrognathia
  • Feeding difficulties
  • Intrauterine growth retardation
  • Talipes equinovarus
  • Delayed skeletal maturation
  • Narrow mouth
  • Gastroesophageal reflux

And another 20 symptoms. If you need more information about this disease we can help you.

Click here to know more about Mendelian.

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— The onset for some of the known clinical features related to this disease may vary, including infantile onset .

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Meier-gorlin Syndrome 2; Mgors2 Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Meier-Gorlin Syndrome Panel.

By Genetic Services Laboratory University of Chicago (United States).

ORC6, CDC6, GMNN, CDT1, ORC1, ORC4
Specificity
17 %
Genes
100 %
Comprehensive Primordial Dwarfism Panel.

By Genetic Services Laboratory University of Chicago (United States).

PLK4, XRCC4, CRIPT, PCNT, ORC6, CENPJ, CDC6, GMNN, RTTN, CDK5RAP2, CUL7, POC1A, CDT1, LARP7, CCDC8, SASS6, CEP63, OBSL1, CEP152, DNA2 , (...)

View the complete list with 8 more genes
Specificity
4 %
Genes
100 %
Microcephaly Sequencing Panel.

By Genetic Services Laboratory University of Chicago (United States).

STIL, SLC2A1, SLC9A6, PLK4, CDKL5, TCF4, UBE3A, WWOX, RAB18, CRIPT, SLC25A19, ZEB2, CASK, TSEN34, ZNF335, ARFGEF2, PCNT, TBC1D20, TUBGCP4, STAMBP , (...)

View the complete list with 50 more genes
Specificity
2 %
Genes
100 %
Microcephaly Deletion/Duplication Panel.

By Genetic Services Laboratory University of Chicago (United States).

STIL, SLC1A4, SLC2A1, SLC9A6, SOX11, PLK4, CDKL5, TCF4, UBE3A, USP18, WWOX, RAB18, CRIPT, SLC25A19, ZEB2, NIN, PPP1R15B, CASK, TSEN34, ZNF335 , (...)

View the complete list with 59 more genes
Specificity
2 %
Genes
100 %
Meier-Gorlin Syndrome 2.

By Molecular Diagnostics Lab Nemours Alfred I. duPont Hospital for Children (United States).

ORC4
Specificity
100 %
Genes
100 %
Meier-Gorlin Syndrome Sequencing Panel with CNV Detection.

By PreventionGenetics PreventionGenetics (United States).

ORC6, CDC6, CDT1, ORC1, ORC4
Specificity
20 %
Genes
100 %
Meier-Gorlin Syndrome via ORC4 Gene Sequencing with CNV Detection.

By PreventionGenetics PreventionGenetics (United States).

ORC4
Specificity
100 %
Genes
100 %
Skeletal Disorders and Joint Problems Sequencing Panel with CNV Detection.

By PreventionGenetics PreventionGenetics (United States).

RMRP, ROR2, RUNX2, SALL1, BMP1, BMP2, BMPR1B, SF3B4, SH3BP2, FBXW4, SHH, SHOX, SKI, SLCO2A1, SLC26A2, SMARCAL1, SMC1A, SOX9, SQSTM1, TBX15 , (...)

View the complete list with 236 more genes
Specificity
1 %
Genes
100 %

You can get up to 22 more panels with our dedicated tool

Learn more

Sources and references

You can check the following sources for additional information.

OMIM Rare Disease Search Engine

If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like MYOPATHY, DISTAL, WITH ANTERIOR TIBIAL ONSET; DMAT EHLERS-DANLOS SYNDROME, TYPE VII, AUTOSOMAL DOMINANT PENDRED SYNDROME; PDS SPASTIC PARAPLEGIA 9A, AUTOSOMAL DOMINANT; SPG9A ANEMIA, HYPOCHROMIC MICROCYTIC, WITH IRON OVERLOAD 2; AHMIO2 ANDROGEN INSENSITIVITY SYNDROME; AIS RETINOBLASTOMA; RB1