Mantle Cell Lymphoma

Description

Mantle cell lymphoma is a rare form of malignant non-Hodgkin lymphoma (see this term) affecting B lymphocytes in the lymph nodes in a region called the ``mantle zone''.

Clinical Features

Top most frequent phenotypes and symptoms related to Mantle Cell Lymphoma

  • Neoplasm
  • Fever
  • Fatigue
  • Splenomegaly
  • Weight loss
  • Lymphadenopathy
  • Lymphoma
  • Anorexia
  • Abnormality of the gastrointestinal tract
  • B-cell lymphoma

And another 5 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Based on the latest data available Mantle Cell Lymphoma have a estimated prevalence of 3.5 per 100k worldwide.
No data available about the known clinical features onset.

Alternative names

Mantle Cell Lymphoma Is also known as mantle zone lymphoma, lcm, mcl.

Researches and researchers

Doctors, researchs, and experts related to Mantle Cell Lymphoma extracted from public data.

Mantle Cell Lymphoma Experts map



Current Researchs and researchers

  • PIERRE-BENITE — Pr Bertrand COIFFIER

    Principal investigator of clinical trial - Investigator of clinical trial - Coordinator of research network

    • Institution/s:
      — CHU de Lyon HCL - GH Sud
      — CHU de Lyon HCL - GH Sud
    • Research area/topic::

      Groupe d'étude des lymphomes de l'adulte


  • PIERRE-BENITE — Pr Gilles SALLES

    Principal investigator of clinical trial - Coordinator of research network

    • Institution/s:
      — CHU de Lyon HCL - GH Sud
      — CHU de Lyon HCL - GH Sud
    • Research area/topic::

      Groupe d'étude des lymphomes de l'adulte


  • MÜNCHEN — Pr Martin DREYLING

    Coordinator of expert centre - Clinical expert - Principal investigator of clinical trial - Coordinator of research network

    • Institution/s:
      — LMU Klinikum der Universität München - Campus Großhadern
      — LMU Klinikum der Universität München - Campus Großhadern
    • Research area/topic::

      European Mantle Cell Lymphoma Network


  • MÜNSTER — Pr Georg LENZ

    Investigator of research project

    • Institution/s:
      — Universitätsklinikum Münster
    • Research area/topic::

      The role of MALT1 in the molecular pathogenesis of mantle cell lymphoma


  • WÜRZBURG — Pr Andreas ROSENWALD

    Responsible for diagnostic tests - Investigator of research project - Manager of biobank/collection - Director of laboratory

    • Institution/s:
      — Institut für Pathologie der Universität Würzburg
    • Research area/topic::

      Molecular pathogenesis of malignant B cell lymphoma



Mendelian

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Mantle Cell Lymphoma Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Hereditary Brain, CNS, PNS Cancer Panel.

By Baylor Miraca Genetics Laboratories (United States).

TP53, VHL, SUFU, PALB2, ALK, APC, MEN1, MLH1, MRE11, MSH2, MSH6, NBN, NF2, ATM, PMS2, PHOX2B, PTCH1
Specificity
6 %
Genes
34 %
Hereditary Brain, CNS, PNS Cancer Panel.

By Baylor Miraca Genetics Laboratories (United States).

TP53, VHL, SUFU, PALB2, ALK, APC, MEN1, MLH1, MRE11, MSH2, MSH6, NBN, NF2, ATM, PMS2, PHOX2B, PTCH1
Specificity
6 %
Genes
34 %
Hereditary Pancreatic Cancer Panel.

By Baylor Miraca Genetics Laboratories (United States).

BMPR1A, BRCA1, BRCA2, STK11, EPCAM, TP53, CDK4, CDKN2A, PALB2, APC, SMAD4, MLH1, MSH2, MSH6, ATM, PMS2, RAD50
Specificity
6 %
Genes
34 %
Hereditary Leukemia/Lymphoma Panel.

By Baylor Miraca Genetics Laboratories (United States).

RUNX1, BRCA2, TP53, CBL, CEBPA, SBDS, BRIP1, PALB2, GATA2, ATM, PAX5, PRF1, PTPN11
Specificity
8 %
Genes
34 %
Comprehensive Hereditary Cancer Panel.

By Baylor Miraca Genetics Laboratories (United States).

RUNX1, SDHA, SDHB, SDHC, SDHD, BMPR1A, BRCA1, BRCA2, STK11, EPCAM, TP53, VHL, WT1, CBL, SUFU, CDC73, CDH1, CDK4, CDKN1C, CDKN2A , (...)

View the complete list with 39 more genes
Specificity
2 %
Genes
34 %
Hereditary Colorectal/Gastrointestinal Cancer Panel.

By Baylor Miraca Genetics Laboratories (United States).

BMPR1A, BRCA1, BRCA2, STK11, EPCAM, TP53, CDH1, CDK4, CDKN2A, PALB2, ENG, APC, SMAD4, MLH1, MSH2, MSH6, MUTYH, ATM, PMS1, PMS2 , (...)

View the complete list with 1 more genes
Specificity
5 %
Genes
34 %
GeneAware Complete Panel Version 2 (Female).

By Baylor Miraca Genetics Laboratories (United States).

RMRP, BCS1L, SACS, BLM, SGCA, SGCB, SGCG, SGSH, SLC12A6, SLC17A5, SLC22A5, SLC25A13, SLC25A15, SLC26A2, SLC35A3, SLC7A7, SMN1, SMPD1, BTD, BTK , (...)

View the complete list with 139 more genes
Specificity
1 %
Genes
34 %
GeneAware Complete Panel Version 2 (Male).

By Baylor Miraca Genetics Laboratories (United States).

RMRP, BCS1L, SACS, BLM, SGCA, SGCB, SGCG, SGSH, SLC12A6, SLC17A5, SLC22A5, SLC25A13, SLC25A15, SLC26A2, SLC35A3, SLC7A7, SMN1, SMPD1, BTD, TGM1 , (...)

View the complete list with 129 more genes
Specificity
1 %
Genes
34 %

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Sources and references

You can check the following sources for additional information.

ORPHANET Rare Disease Symptoms Checker

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