Ligneous Conjunctivitis

Description

Ligneous conjunctivitis (LC) is a rare form of chronic conjunctivitis characterised by the recurrent formation of pseudomembranous lesions most commonly on the palpebral surfaces. It is most frequently reported as a clinical manifestation of severe homozygous or compound-heterozygous hypoplasminogenemia (see this term).

Clinical Features

Top most frequent phenotypes and symptoms related to Ligneous Conjunctivitis

  • Global developmental delay
  • Hyperreflexia
  • Macrocephaly
  • Hydrocephalus
  • Blindness
  • Cerebellar hypoplasia
  • Papule
  • Dandy-Walker malformation
  • Recurrent otitis media
  • Nephrolithiasis

And another 25 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
No data available about the known clinical features onset.

Alternative names

Ligneous Conjunctivitis Is also known as conjunctivitis lignosa.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.


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Ligneous Conjunctivitis Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Genetic Renal Panel.

By Molecular Otolaryngology and Renal Research Laboratories University of Iowa Hospital and Clinics (United States).

CFB, THBD, C3, ADAMTS13, CFHR3, MMACHC, CFHR5, DGKE, CFH, CFHR1, CFI, CD46, PLG
Specificity
8 %
Genes
100 %
PLG Sequencing.

By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center (United States).

PLG
Specificity
100 %
Genes
100 %
PLG Deletion/duplication analysis.

By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center (United States).

PLG
Specificity
100 %
Genes
100 %
Plasminogen deficiency type I (sequence analysis of PLG gene).

By CGC Genetics (Portugal).

PLG
Specificity
100 %
Genes
100 %
Plasminogen deficiency type 1.

By Centogene AG - the Rare Disease Company (Germany).

PLG
Specificity
100 %
Genes
100 %
PLG.

By Fulgent Genetics Fulgent Genetics (United States).

PLG
Specificity
100 %
Genes
100 %
PLASMINOGEN DEFICIENCY.

By Laboratorio de Genetica Clinica SL (Spain).

PLG
Specificity
100 %
Genes
100 %
ATYPICAL HEMOLYTIC UREMIC SYNDROME: NGS PANEL.

By Laboratorio de Genetica Clinica SL (Spain).

CFB, THBD, C1S, C2, C3, C3AR1, C8A, C9, CFHR4, CFHR3, CR1, CR2, MMACHC, CFHR5, DGKE, F12, CFH, CFHR1, CFHR2, CFI , (...)

View the complete list with 4 more genes
Specificity
5 %
Genes
100 %

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Sources and references

You can check the following sources for additional information.

ORPHANET Rare Disease Symptoms Checker

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