Leukemia, Acute Lymphoblastic; All

Incidence and onset information

Researches and researchers

Doctors, researchs, and experts related to Leukemia, Acute Lymphoblastic; All extracted from public data.

Leukemia, Acute Lymphoblastic; All Experts map

Current Researchs and researchers

• INNSBRUCK — ST. ANNA KINDERKREBSFORSCHUNG

  Investigator of research project - Sponsor of clinical trial - Sponsor of multinational clinical trial
  
  

  • Institution/s:
    — St. Anna Kinderkrebsforschung
    — Department für Kinder- und Jugendheilkunde, Medizinische Universität Innsbruck
  • Research area/topic::
    

    IntReALL 2010: International study for treatment of childhood relapsed ALL 2010 with standard therapy, systematic integration of new agents, and establishment of standardized diagnostic and research - AT



• WIEN — Pr Renate PANZER-GRÜMAYER

  Investigator of research project
  
  

  • Institution/s:
    — St. Anna Kinderkrebsforschung
  • Research area/topic::
    

    Translational Research in Childhood Acute Lymphoblastic Leukemia (TRANSCALL)



• WIEN — ST. ANNA KINDERKREBSFORSCHUNG

  Investigator of research project - Sponsor of clinical trial - Sponsor of multinational clinical trial
  
  

  • Institution/s:
    — St. Anna Kinderkrebsforschung
    — Department für Kinder- und Jugendheilkunde, Medizinische Universität Innsbruck
  • Research area/topic::
    

    IntReALL 2010: International study for treatment of childhood relapsed ALL 2010 with standard therapy, systematic integration of new agents, and establishment of standardized diagnostic and research - AT



• WIEN — Dr Andrea HÖLBL-KOVACIC

  Investigator of research project
  
  

  • Institution/s:
    — Department für Biomedizinische Wissenschaften, Veterinärmedizinische Universität Wien
  • Research area/topic::
    

    Stat5 serine phosphorylation in Bcr/Abl-induced leukemia



• WIEN — Pr Veronika SEXL

  Investigator of research project
  
  

  • Institution/s:
    — Department für Biomedizinische Wissenschaften, Veterinärmedizinische Universität Wien
  • Research area/topic::
    

    Uncoupling CDK6 from p16INK4A - effects for hematopoiesis and lymphomagenesis



• GENT — Pr Pieter VAN VLIERBERGHE

  Investigator of research project
  
  

  • Institution/s:
    — Ghent University Hospital, Center for Medical Genetics Gent
  • Research area/topic::
    

    Dynamic interplay between DNA methylation, histone modifications and the activity of super enhancers in the pathogenesis of immature T-ALL



• TAMPERE — Dr Olli LOHI

  Coordinator of expert centre - Investigator of research project
  
  

  • Institution/s:
    — University of Tampere
    — TAYS - Tampere University Hospital
  • Research area/topic::
    

    The pathogenesis of childhood acute leukemia



• TURKU — Dr Päivi LÄHTEENMÄKI

  Clinical expert - Investigator of research project
  
  

  • Institution/s:
    — Turku University Hospital
  • Research area/topic::
    

    IntReALL 2010:International study for treatment of childhood relapsed ALL 2010 with standard therapy, systematic integration of new agents, and establishment of standardized diagnostic and research - FI



• BESANÇON — Pr Pierre-Simon ROHRLICH

  Coordinator of expert centre - Clinical expert - Principal investigator of clinical trial - Investigator of research project
  
  

  • Institution/s:
    — CHU de Nice - Hôpital l'Archet 1
    — CHRU de Besançon - Hôpital Jean Minjoz
  • Research area/topic::
    

    IntReALL 2010: International study for treatment of childhood relapsed ALL 2010 with standard therapy, systematic integration of new agents, and establishment of standardized diagnostic and research - FR



• MARSEILLE — Pr Pascal AUQUIER

  Investigator of research project - Manager of registry
  
  

  • Institution/s:
    — EA 3279 - Laboratoire de santé publique, CHU de Marseille - Hôpital de la Timone
  • Research area/topic::
    

    multicentric prospective cohort of childhood and teenager leukemia: determinants of health status and quality of life of patients after treatment of an acute leukemia of childhood - LEA



• NICE — Pr Pierre-Simon ROHRLICH

  Coordinator of expert centre - Clinical expert - Principal investigator of clinical trial - Investigator of research project
  
  

  • Institution/s:
    — CHU de Nice - Hôpital l'Archet 1
    — CHRU de Besançon - Hôpital Jean Minjoz
  • Research area/topic::
    

    IntReALL 2010: International study for treatment of childhood relapsed ALL 2010 with standard therapy, systematic integration of new agents, and establishment of standardized diagnostic and research - FR



• PARIS — Pr Hervé DOMBRET

  Principal investigator of clinical trial - Coordinator of research network
  
  

  • Institution/s:
    — CHU Paris-GH St-Louis Lariboisière F.Widal - Hôpital Saint-Louis
  • Research area/topic::
    

    Study and research group in adult acute lymphoblastic leukemia



• PARIS — Dr Vincent GREK

  Investigator of research project - Coordinator of research network
  
  

  • Institution/s:
    — Only For Children Pharmaceuticals
  • Research area/topic::
    

    LOULLA&PHILLA: development of 6-mercaptopurine and methotrexate oral liquid formulations for the maintenance treatment of Acute Lymphoblastic Leukemia in children (coordination)



• PARIS — Pr André BARUCHEL

  Clinical expert - Principal investigator of clinical trial - Investigator of research project
  
  

  • Institution/s:
    — Pôle de pédiatrie médicale, CHU Paris - Hôpital Robert Debré
  • Research area/topic::
    

    CAL-FB-01: Franco-Belgian protocol of treatment of acute lymphoblastic leukemia in children and adolescents



• — Institution: Information not provided - DE

  
  
  

  • Institution/s:
    — Institution: Information not provided - DE
  • Research area/topic::
    

    IRMA-4-ALL : Microfluidic integration of the laboratory processes of the test into a centrifugal test carrier



• BERLIN — Pr Christian HAGEMEIER

  Coordinator of research network
  
  

  • Institution/s:
    — Otto-Heubner-Centrum für Kinder- und Jugendmedizin
  • Research area/topic::
    

    NGFN plus: Leukemia Network - functional and translational studies on acute lymphoblastic leukemia in childhood -terminated



• BERLIN — Dr Arend VON STACKELBERG

  Coordinator of expert centre - Clinical expert - Principal investigator of clinical trial - Investigator of research project - Coordinator of research network
  
  

  • Institution/s:
    — Charité - Universitätsmedizin Berlin (CVK)
    — Otto-Heubner-Centrum für Kinder- und Jugendmedizin
  • Research area/topic::
    

    ALL-REZ BFM: Observational study biobank for children with Acute Lymphoblastic Leukemia



• DRESDEN — Pr Alexander STORCH

  Clinical expert - Investigator of research project - Director of department
  
  

  • Institution/s:
    — Universitätsklinikum Carl Gustav Carus an der TU Dresden
    — Klinik und Poliklinik für Neurologie, Universitätsklinikum Carl Gustav Carus an der TU Dresden
  • Research area/topic::
    

    Longitudinal investigation of hippocampal function and morphology in patients with Acute Lymphocytic Leukemia treated with Chemotherapy: A Monocentric, interdisciplinary pilot study



• ERLANGEN — Dr Thorsten LANGER

  Investigator of research project
  
  

  • Institution/s:
    — Kinder- und Jugendklinik des Universitätsklinikums Erlangen
  • Research area/topic::
    

    Late Effects Surveillance System (LESS) for oncological diseases in children und adolescents



• FRANKFURT AM MAIN — Pr Hubert SERVE

  Coordinator of expert centre - Clinical expert - Principal investigator of clinical trial - Investigator of research project - Director of department
  
  

  • Institution/s:
    — Zentrum der Inneren Medizin, Klinikum der Johann Wolfgang Goethe-Universität Frankfurt
    — Universitäres Centrum für Tumorerkrankungen (UCT) Frankfurt
  • Research area/topic::
    

    Pathological gene products and their disease mechanisms: Oncogenic cytokine signaling in acute lymphoblastic leukemia (P2)



• MANNHEIM — Dr Susanne SAUßELE

  Coordinator of expert centre - Clinical expert - Principal investigator of clinical trial - Investigator of research project - Coordinator of research network
  
  

  • Institution/s:
    — III. Medizinische Universitäts-Klinik, Universitätsklinikum Mannheim
    — Universitätsmedizin Mannheim
  • Research area/topic::
    

    Competence Network 'acute and chronic leukemias'



• MANNHEIM — Pr Rüdiger HEHLMANN

  Principal investigator of clinical trial - Investigator of research project - Coordinator of research network - Director of department
  
  

  • Institution/s:
    — III. Medizinische Universitäts-Klinik, Universitätsklinikum Mannheim
    — Universitätsklinikum Mannheim
  • Research area/topic::
    

    EUROPEAN LEUKEMIA NET: Strengthen and develop scientific and technological excellence in research and therapy of leukemia (coordination)



• PERUGIA — Pr Cristina MECUCCI

  Clinical expert - Responsible for diagnostic tests - Investigator of research project - Director of laboratory - Quality manager
  
  

  • Institution/s:
    — Università degli Studi di Perugia - Ospedale S. Maria della Misericordia
  • Research area/topic::
    

    Characterization of chromosomal breakpoints in hematological malignancies using molecular cytogenetics



• ROMA — Pr Franco LOCATELLI

  Coordinator of expert centre - Principal investigator of clinical trial - Investigator of clinical trial - Investigator of research project
  
  

  • Institution/s:
    — Dipartimento di Onco-Ematologia Pediatrica e Medicina Trasfusionale, IRCCS Ospedale Pediatrico Bambino Gesù - SEDE GIANICOLO
  • Research area/topic::
    

    IntReALL 2010: International study for treatment of childhood relapsed ALL 2010 with standard therapy, systematic integration of new agents, and establishment of standardized diagnostic and research - IT



• WROCLAW — Pr Ewa GORCZYNSKA

  Investigator of research project
  
  

  • Institution/s:
    — Ponadregionalne Centrum Onkologii Dzieciecej PRZYLADEK NADZIEI
  • Research area/topic::
    

    IntReALL 2010:International study for treatment of childhood relapsed ALL 2010 with standard therapy, systematic integration of new agents, and establishment of standardized diagnostic and research - PL



• LISBOA — Pr João T BARATA

  Investigator of research project - Director of laboratory
  
  

  • Institution/s:
    — Instituto de Medicina Molecular - Faculdade de Medicina da Universidade de Lisboa, Faculdade de Medicina da Universidade de Lisboa
  • Research area/topic::
    

    Cell-intrinsic and microenvironmental signals intertwined: novel targets for therapeutic intervention in acute lymphoblastic leukemia.



• PORTO — Mr João LACERDA

  Investigator of research project
  
  

  • Institution/s:
    — Hospital de Santo António - Centro Hospitalar do Porto
  • Research area/topic::
    

    Clinical implications of activation of PI3K/Akt signaling pathway in primary adult acute lymphoblastic leukemia.



• LUND — Dr Jens NYGREN

  Investigator of research project
  
  

  • Institution/s:
    — Lund University
  • Research area/topic::
    

    Hematopoietic stem cell proliferation in development and in acute lymphoblastic leukemia



• STOCKHOLM — Dr Annika WALLBERG

  Investigator of research project
  
  

  • Institution/s:
    — Karolinska Institutet - Solna
  • Research area/topic::
    

    Transcriptional mechanisms by Notch and E2A proteins in lymphocyte development and ALL

Leukemia, Acute Lymphoblastic; All Recommended genes panels

Panel Name, Specifity and genes Tested/covered
FLT3 genotyping. By Molecular Genetics Diagnostic Laboratory Detroit Medical Center University Laboratories (United States). FLT3 Specificity 100 % Genes 12 %
MyeloidDx by NGS. By Molecular Genetics Diagnostic Laboratory Detroit Medical Center University Laboratories (United States). RUNX1, SF3B1, SRSF2, BRAF, SMC1A, STAG2, TP53, U2AF1, KDM6A, WT1, IKZF1, CALR, CBL, CBLB, SETBP1, FBXW7, CDKN2A, PHF6, ASXL1, CEBPA , (...) View the complete list with 32 more genes Panel complete gene list RUNX1, SF3B1, SRSF2, BRAF, SMC1A, STAG2, TP53, U2AF1, KDM6A, WT1, IKZF1, CALR, CBL, CBLB, SETBP1, FBXW7, CDKN2A, PHF6, ASXL1, CEBPA, BCOR, ZRSR2, CSF3R, SMC3, CUX1, BCORL1, TET2, DNMT3A, ETV6, EZH2, FLT3, GATA1, GATA2, GNAS, HRAS, IDH1, IDH2, JAK2, JAK3, KIT, KRAS, MPL, MYD88, ABL1, NOTCH1, NPM1, NRAS, PDGFRA, ATRX, PTEN, PTPN11, RAD21 Close Specificity 4 % Genes 23 %
MyeloidDx by NGS. By Molecular Genetics Diagnostic Laboratory Detroit Medical Center University Laboratories (United States). RUNX1, SF3B1, SRSF2, BRAF, SMC1A, STAG2, TP53, U2AF1, KDM6A, WT1, IKZF1, CALR, CBL, CBLB, SETBP1, CBLC, FBXW7, CDKN2A, PHF6, CEBPA , (...) View the complete list with 31 more genes Panel complete gene list RUNX1, SF3B1, SRSF2, BRAF, SMC1A, STAG2, TP53, U2AF1, KDM6A, WT1, IKZF1, CALR, CBL, CBLB, SETBP1, CBLC, FBXW7, CDKN2A, PHF6, CEBPA, BCOR, ZRSR2, CSF3R, SMC3, CUX1, BCORL1, DNMT3A, ETV6, EZH2, FLT3, GATA1, GATA2, GNAS, HRAS, IDH1, IDH2, JAK2, JAK3, KIT, KRAS, MPL, MYD88, ABL1, NOTCH1, NPM1, NRAS, PDGFRA, ATRX, PTEN, PTPN11, RAD21 Close Specificity 4 % Genes 23 %
FLT3 Molecular Genetic Testing. By Michigan State University Clinical Genetics Laboratory Michigan State University (United States). FLT3 Specificity 100 % Genes 12 %
Acute myeloid leukemia (AML, sequence analysis of FLT3 gene). By CGC Genetics (Portugal). FLT3 Specificity 100 % Genes 12 %
Detection of ITD and TKD mutations on FLT3 gene. By CGC Genetics (Portugal). FLT3 Specificity 100 % Genes 12 %
FLT3 ITD, NPM1 targeted mutation testing. By Molecular Diagnostics Laboratory University of Toledo Medical Center (United States). FLT3, NPM1 Specificity 50 % Genes 12 %
Myeloid Tumor Panel. By Centogene AG - the Rare Disease Company (Germany). RUNX1, SF3B1, SRSF2, BRAF, SMC1A, STAG2, TP53, U2AF1, KDM6A, WT1, IKZF1, CALR, CBL, CBLB, SETBP1, CBLC, FBXW7, CDKN2A, PHF6, ASXL1 , (...) View the complete list with 33 more genes Panel complete gene list RUNX1, SF3B1, SRSF2, BRAF, SMC1A, STAG2, TP53, U2AF1, KDM6A, WT1, IKZF1, CALR, CBL, CBLB, SETBP1, CBLC, FBXW7, CDKN2A, PHF6, ASXL1, CEBPA, BCOR, ZRSR2, CSF3R, SMC3, CUX1, BCORL1, TET2, DNMT3A, ETV6, EZH2, FLT3, GATA1, GATA2, GNAS, HRAS, IDH1, IDH2, JAK2, JAK3, KIT, KRAS, MPL, MYD88, ABL1, NOTCH1, NPM1, NRAS, PDGFRA, ATRX, PTEN, PTPN11, RAD21 Close Specificity 4 % Genes 23 %

Sources and references

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