Intervertebral Disc Disease; Idd

Description

Lumbar disc disease is caused by degeneration of intervertebral discs of the lumbar spine. One of the most common musculoskeletal disorders, it has strong genetic determinants (Matsui et al., 1998; Battie et al., 1995; Sambrook et al., 1999).

Clinical Features

Phenotypes and symptoms related to Intervertebral Disc Disease; Idd

  • Pain
  • Back pain
  • Vertebral fusion
  • Low back pain
  • Intervertebral disc degeneration
  • Sciatica

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
No data available about the known clinical features onset.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Intervertebral Disc Disease; Idd Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Hearing Loss Advanced Sequencing and CNV Evaluation.

By Athena Diagnostics Inc (United States).

BCS1L, ROR1, SALL1, SEMA3E, SIX1, SIX5, SLC12A1, SLC19A2, SLC22A4, SNAI2, SMPX, SOX10, TBX1, TCOF1, TECTA, TFAP2A, TIMM8A, TJP2, TMPRSS3, USH1C , (...)

View the complete list with 149 more genes
Specificity
2 %
Genes
40 %
Connective Tissue Disorders Panel.

By Human Genetics Laboratory, Munroe-Meyer Institute University of Nebraska Medical Center (United States).

BGN, SKI, TGFB2, TGFB3, TGFBR1, TGFBR2, MED12, TNXB, C1R, C1S, ACTA2, ADAMTS10, SLC2A10, ADAMTSL2, CBS, TAB2, B3GALT6, ATP6V0A2, FKBP14, RIN2 , (...)

View the complete list with 45 more genes
Specificity
4 %
Genes
40 %
Stickler Syndrome Panel.

By Human Genetics Laboratory, Munroe-Meyer Institute University of Nebraska Medical Center (United States).

COL11A1, COL11A2, COL9A1, COL9A2, COL9A3
Specificity
40 %
Genes
40 %
COL9A3. Sequencing of the exons 2, 3 and 4.

By Instituto de Medicina Genomica Instituto de Medicina Genomica (Spain).

COL9A3
Specificity
100 %
Genes
20 %
Audiome (hearing loss panel).

By Division of Genomic Diagnostics The Children's Hospital of Philadelphia (United States).

BCS1L, SIX1, SNAI2, SMPX, SOX10, SUCLA2, TECTA, TIMM8A, TMPRSS3, USH1C, USH2A, CLRN1, TSPEAR, WFS1, ESPN, CLIC5, CDH23, CABP2, PCDH15, OSBPL2 , (...)

View the complete list with 85 more genes
Specificity
2 %
Genes
40 %
Syndromic deafness (NGS panel for 62 genes).

By CGC Genetics (Portugal).

SEMA3E, SIX1, SIX5, SLC19A2, SNAI2, SOX10, TCOF1, TFAP2A, TIMM8A, TYR, USH1C, USH2A, CLRN1, WFS1, CDH23, CACNA1D, PCDH15, ANKH, ABHD12, CD151 , (...)

View the complete list with 41 more genes
Specificity
4 %
Genes
40 %
Epiphyseal dysplasia multiple (NGS panel for 7 gene).

By CGC Genetics (Portugal).

SLC26A2, COL9A1, COL9A2, COL9A3, COMP, MATN3
Specificity
17 %
Genes
20 %
Syndromic and non syndromic deafness (NGS panel for 127 genes).

By CGC Genetics (Portugal).

SEMA3E, SIX1, SIX5, SLC12A1, SLC19A2, SNAI2, SMPX, SOX10, TCOF1, TECTA, TFAP2A, TIMM8A, TJP2, TMPRSS3, TYR, USH1C, USH2A, CLRN1, TSPEAR, WFS1 , (...)

View the complete list with 105 more genes
Specificity
2 %
Genes
40 %

You can get up to 151 more panels with our dedicated tool

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Sources and references

You can check the following sources for additional information.

OMIM MESH Rare Disease Symptoms Checker

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