Insulinoma

Description

Insulinoma is the most common type of functioning pancreatic neuroendocrine tumor (see this term) characterized most commonly by a solitary, small pancreatic lesion that causes hyperinsulinemic hypoglycemia.

Clinical Features

Top most frequent phenotypes and symptoms related to Insulinoma

  • Seizures
  • Tremor
  • Fatigue
  • Behavioral abnormality
  • Hyperhidrosis
  • Anxiety
  • Lethargy
  • Paresthesia
  • Coma
  • Generalized muscle weakness

And another 24 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Based on the latest data available INSULINOMA have a estimated incidence of 0.25 per 100k in Europe.
No data available about the known clinical features onset.

Researches and researchers

Doctors, researchs, and experts related to Insulinoma extracted from public data.

Insulinoma Experts map



Current Researchs and researchers

  • 'T HARDE — Mr T. [Ton] VAN DEN HOVEN

    Investigator of research project

    • Institution/s:
      — SurgVision BV
    • Research area/topic::

      BETACURE: Personalized diagnosis and treatment of hyperinsulinemic hypoglycaemia caused by beta-cell pathology - NL


  • GRONINGEN — Pr G.M. [Gooitzen] VAN DAM

    Investigator of research project

    • Institution/s:
      — UMCG - Universitair Medisch Centrum Groningen
    • Research area/topic::

      BETACURE: Personalized diagnosis and treatment of hyperinsulinemic hypoglycaemia caused by beta-cell pathology - NL



Mendelian

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Insulinoma Recommended genes panels

Panel Name, Specifity and genes Tested/covered
MitoMetĀ®Plus aCGH Analysis.

By Baylor Miraca Genetics Laboratories (United States).

RGS9, RHO, GRK1, RLBP1, RNASEL, BCS1L, RP1, RP2, RP9, RPE65, RPGR, RPL35A, MRPL3, RPS14, RS1, SAG, SARDH, SCO2, SCP2, SDHB , (...)

View the complete list with 612 more genes
Specificity
1 %
Genes
100 %
Hereditary Brain, CNS, PNS Cancer Panel.

By Baylor Miraca Genetics Laboratories (United States).

TP53, VHL, SUFU, PALB2, ALK, APC, MEN1, MLH1, MRE11, MSH2, MSH6, NBN, NF2, ATM, PMS2, PHOX2B, PTCH1
Specificity
6 %
Genes
100 %
Hereditary Brain, CNS, PNS Cancer Panel.

By Baylor Miraca Genetics Laboratories (United States).

TP53, VHL, SUFU, PALB2, ALK, APC, MEN1, MLH1, MRE11, MSH2, MSH6, NBN, NF2, ATM, PMS2, PHOX2B, PTCH1
Specificity
6 %
Genes
100 %
Hereditary Endocrine Cancer Panel.

By Baylor Miraca Genetics Laboratories (United States).

SDHA, SDHB, SDHC, SDHD, TP53, VHL, CDC73, SDHAF2, TMEM127, MAX, MEN1, PRKAR1A, PTEN, RET
Specificity
8 %
Genes
100 %
Comprehensive Hereditary Cancer Panel.

By Baylor Miraca Genetics Laboratories (United States).

RUNX1, SDHA, SDHB, SDHC, SDHD, BMPR1A, BRCA1, BRCA2, STK11, EPCAM, TP53, VHL, WT1, CBL, SUFU, CDC73, CDH1, CDK4, CDKN1C, CDKN2A , (...)

View the complete list with 39 more genes
Specificity
2 %
Genes
100 %
MEN1 DNA Sequencing Test.

By Athena Diagnostics Inc (United States).

MEN1
Specificity
100 %
Genes
100 %
Multiple endocrine neoplasia, type 1.

By Center for Human Genetics, Inc (United States).

MEN1
Specificity
100 %
Genes
100 %
Inherited Cancer Panel.

By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University (United States).

BLM, SDHB, BMPR1A, BRCA1, BRCA2, STK11, EPCAM, TP53, TSC1, TSC2, VHL, XRCC2, CDC73, CDH1, CDK4, CDKN1B, CDKN2A, BRIP1, SDHAF2, TMEM127 , (...)

View the complete list with 28 more genes
Specificity
3 %
Genes
100 %

We have 143 more panels available in our App

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Sources and references

You can check the following sources for additional information.

ORPHANET Genetic Syndrome Finder

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