Ichthyosis Vulgaris

Description

The most common form of ichthyosis. It is an autosomal dominant inherited or acquired disorder characterized by scaling and desquamation of the skin.

Clinical Features

Top most frequent phenotypes and symptoms related to Ichthyosis Vulgaris

  • Fever
  • Hyperkeratosis
  • Ichthyosis
  • Asthma
  • Eczema
  • Epidermal acanthosis
  • Scaling skin
  • Heat intolerance
  • Allergic rhinitis
  • Eczematoid dermatitis

And another 1 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
No data available about the known clinical features onset.

Alternative names

Ichthyosis Vulgaris Is also known as ichthyosis simplex.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.


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Ichthyosis Vulgaris Recommended genes panels

Panel Name, Specifity and genes Tested/covered
FLG.

By Institute for Human Genetics University Clinic Freiburg (Germany).

FLG
Specificity
100 %
Genes
50 %
FLG (Filaggrin) Hot Spots.

By GeneDx (United States).

FLG
Specificity
100 %
Genes
50 %
FLG. Detection of the mutation p.Arg501X by sequencing.

By Instituto de Medicina Genomica Instituto de Medicina Genomica (Spain).

FLG
Specificity
100 %
Genes
50 %
FLG. Complete sequencing.

By Instituto de Medicina Genomica Instituto de Medicina Genomica (Spain).

FLG
Specificity
100 %
Genes
50 %
Ichthyosis Vulgaris (sequence analysis of FLG gene).

By CGC Genetics (Portugal).

FLG
Specificity
100 %
Genes
50 %
Ichthyosis Vulgaris (p.Arg501* and p.Ser761Cysfs*36 frequent mutations on FLG gene).

By CGC Genetics (Portugal).

FLG
Specificity
100 %
Genes
50 %
Ichthyosis Deletion / Duplication panel.

By Connective Tissue Gene Tests (United States).

ST14, STS, SULT2B1, TGM1, TGM5, ALOXE3, ABCA12, CASP14, CHST8, CDSN, POMP, PNPLA1, LIPN, CERS3, CSTA, CYP4F22, NIPAL4, FLG, KDSR, GJA1 , (...)

View the complete list with 7 more genes
Specificity
4 %
Genes
50 %
Ichthyosis NGS panel.

By Connective Tissue Gene Tests (United States).

ST14, STS, SULT2B1, TGM1, TGM5, ALOXE3, ABCA12, CASP14, CHST8, CDSN, POMP, PNPLA1, LIPN, CERS3, CSTA, CYP4F22, NIPAL4, FLG, KDSR, GJA1 , (...)

View the complete list with 7 more genes
Specificity
4 %
Genes
50 %

We have 14 more panels available in our App

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Sources and references

You can check the following sources for additional information.

OMIM MESH Rare Disease Symptoms Checker

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