Hepatitis B Virus, Susceptibility To

Description

HBV is a DNA virus that enters the liver via the bloodstream, and replication occurs only in liver tissue. Transmission occurs by percutaneous or mucosal exposure to infected blood or other body fluids. Approximately one third of all cases of cirrhosis and half of all cases of hepatocellular carcinoma (HCC ) can be attributed to chronic HBV infection. Worldwide, 2 billion people have been infected with HBV, 360 million have chronic infection, and 600,000 die each year from HBV-related liver disease or HCC. However, there is marked geographic variability in HBV prevalence, with chronic infection affecting less than 2% of the populations of North America and western and northern Europe; between 2 and 7% of the populations of eastern and central Europe, the Amazon basin, the Middle East, and the Indian subcontinent; and more than 8% of the populations of Asia, sub-Saharan Africa, and the Pacific (Seeff and Hoofnagle, 2006; Shepard et al., 2006).

Clinical Features

Top most frequent phenotypes and symptoms related to Hepatitis B Virus, Susceptibility To

  • Pain
  • Hepatomegaly
  • Fever
  • Vomiting
  • Splenomegaly
  • Abdominal pain
  • Jaundice
  • Carcinoma
  • Abnormality of the liver
  • Nausea

And another 10 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
No data available about the known clinical features onset.

Alternative names

Hepatitis B Virus, Susceptibility To Is also known as hbv, susceptibility to.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Hepatitis B Virus, Susceptibility To Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Interferon-gamma Receptor Deficiency: IFNGR1 (Full Gene Sequencing).

By Molecular Diagnostic Laboratory University of Alberta (Canada).

IFNGR1
Specificity
100 %
Genes
34 %
Interferon-gamma Receptor Deficiency: IFNGR1 (Known Mutation).

By Molecular Diagnostic Laboratory University of Alberta (Canada).

IFNGR1
Specificity
100 %
Genes
34 %
Interferon-gamma Receptor Deficiency: Two-gene Profile (IFNGR1, IFNGR2) (Full Gene Sequencing).

By Molecular Diagnostic Laboratory University of Alberta (Canada).

IFNGR1, IFNGR2
Specificity
50 %
Genes
34 %
IFNGR1 Sequencing.

By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center (United States).

IFNGR1
Specificity
100 %
Genes
34 %
IFNGR1 Deletion/duplication analysis.

By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center (United States).

IFNGR1
Specificity
100 %
Genes
34 %
Immunodeficiency 27A, mycobacteriosis AR (sequence analysis of IFNGR1 gene).

By CGC Genetics (Portugal).

IFNGR1
Specificity
100 %
Genes
34 %
Mycobacterial infection, atypical, familial disseminated.

By Centogene AG - the Rare Disease Company (Germany).

IFNGR1
Specificity
100 %
Genes
34 %
Defects of phagocytosis Panel.

By CeGaT GmbH (Germany).

STAT1, TAZ, TCIRG1, TCN2, TERT, WAS, WIPF1, ACTB, VPS45, HPS3, HPS4, HAX1, HPS5, DTNBP1, CEBPE, HPS6, SBDS, SLC35C1, BLOC1S3, VPS13B , (...)

View the complete list with 39 more genes
Specificity
2 %
Genes
34 %

You can get up to 23 more panels with our dedicated tool

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Sources and references

You can check the following sources for additional information.

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