Helicobacter Pylori Infection, Susceptibility To

Description

Helicobacter pylori is a microaerophilic, gram-negative bacterium that colonizes the gastric mucosa of approximately 50% of the world's population, and is a primary pathogenic factor in benign and malignant gastroduodenal disease (Warren and Marshall, 1983; Blaser and Parsonnet, 1994). Tomb et al. (1997) reported the complete sequence of the circular genome of H. pylori. The 1,667,867-bp genome contains 1,590 predicted coding sequences (genes). Sequence analysis of these genes indicated that the organism has systems for motility, for scavenging iron, and for DNA restriction and modification. Its survival in acid conditions depends, in part, on its ability to establish a positive inside-membrane potential in low pH.

Clinical Features

Phenotypes and symptoms related to Helicobacter Pylori Infection, Susceptibility To

  • Helicobacter pylori infection

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
No data available about the known clinical features onset.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.


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Helicobacter Pylori Infection, Susceptibility To Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Interferon-gamma Receptor Deficiency: IFNGR1 (Full Gene Sequencing).

By Molecular Diagnostic Laboratory University of Alberta (Canada).

IFNGR1
Specificity
100 %
Genes
100 %
Interferon-gamma Receptor Deficiency: IFNGR1 (Known Mutation).

By Molecular Diagnostic Laboratory University of Alberta (Canada).

IFNGR1
Specificity
100 %
Genes
100 %
Interferon-gamma Receptor Deficiency: Two-gene Profile (IFNGR1, IFNGR2) (Full Gene Sequencing).

By Molecular Diagnostic Laboratory University of Alberta (Canada).

IFNGR1, IFNGR2
Specificity
50 %
Genes
100 %
IFNGR1 Sequencing.

By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center (United States).

IFNGR1
Specificity
100 %
Genes
100 %
IFNGR1 Deletion/duplication analysis.

By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center (United States).

IFNGR1
Specificity
100 %
Genes
100 %
Immunodeficiency 27A, mycobacteriosis AR (sequence analysis of IFNGR1 gene).

By CGC Genetics (Portugal).

IFNGR1
Specificity
100 %
Genes
100 %
Mycobacterial infection, atypical, familial disseminated.

By Centogene AG - the Rare Disease Company (Germany).

IFNGR1
Specificity
100 %
Genes
100 %
Defects of phagocytosis Panel.

By CeGaT GmbH (Germany).

STAT1, TAZ, TCIRG1, TCN2, TERT, WAS, WIPF1, ACTB, VPS45, HPS3, HPS4, HAX1, HPS5, DTNBP1, CEBPE, HPS6, SBDS, SLC35C1, BLOC1S3, VPS13B , (...)

View the complete list with 39 more genes
Specificity
2 %
Genes
100 %

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Sources and references

You can check the following sources for additional information.

OMIM Rare Disease Symptoms Checker

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