Grange syndrome is characterised by stenosis or occlusion of multiple arteries (including the renal, cerebral and abdominal vessels), hypertension, brachysyndactyly, syndactyly, increased bone fragility, and learning difficulties or borderline intellectual deficit. Congenital heart defects were also reported in some cases.
Genes related to Grange Syndrome
Clinical FeaturesTop most frequent phenotypes and symptoms related to Grange Syndrome
- Intellectual disability
- Failure to thrive
- Abnormal facial shape
- Ventricular septal defect
- Renal insufficiency
And another 25 symptoms. If you need more information about this disease we can help you.
Incidence and onset information— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.
Grange Syndrome Is also known as arterial occlusive disease, progressive, with hypertension, heart defects, bone fragility, and brachysyndactyly, grange occlusive arterial syndrome, progressive arterial occlusive disease-hypertension-heart defects-bone fragility-brachysyndactyly syndrome.
Researches and researchersCurrently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.
Grange Syndrome Recommended genes panels
|Panel Name, Specifity and genes Tested/covered|
By Fulgent Genetics Fulgent Genetics (United States).
By Foundation Medicine, Inc. (United States).
BCL6, BCL7A, ROS1, RUNX1, BLM, SDHA, SDHB, SDHC, SDHD, SF3B1, SRSF2, SGK1, FOXL2, BRAF, BRCA1, BRCA2, SMARCA1, SMARCA4, SMARCB1, ARID1A , (...)
View the complete list with 374 more genes
You can get up to -6 more panels with our dedicated toolLearn more
Sources and references
You can check the following sources for additional information.OMIM ORPHANET MESH Genetic Syndrome Finder
If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like MORNING GLORY SYNDROME CRANIOSYNOSTOSIS 5, SUSCEPTIBILITY TO; CRS5 COMPLEMENT COMPONENT 8 DEFICIENCY, TYPE I; C8D1