Glomerulopathy With Fibronectin Deposits 1; Gfnd1
Glomerulopathy with fibronectin deposits (GFND) is a genetically heterogeneous autosomal dominant disorder characterized clinically by proteinuria, microscopic hematuria, and hypertension that leads to end-stage renal failure in the second to fifth decade of life. Pathologic examination shows enlarged glomeruli with mesangial and subendothelial fibrillary deposits that show strong immunoreactivity to fibronectin (FN1 ) (Castelletti et al., 2008).
Clinical FeaturesTop most frequent phenotypes and symptoms related to Glomerulopathy With Fibronectin Deposits 1; Gfnd1
- Renal insufficiency
- Stage 5 chronic kidney disease
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Incidence and onset information— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.
Glomerulopathy With Fibronectin Deposits 1; Gfnd1 Is also known as glomerulopathy with giant fibrillar deposits, lobular glomerulopathy, familial.
Researches and researchersCurrently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.
Sources and references
You can check the following sources for additional information.OMIM Genetic Syndrome Finder
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