Glomerulopathy With Fibronectin Deposits 1; Gfnd1
Glomerulopathy with fibronectin deposits (GFND) is a genetically heterogeneous autosomal dominant disorder characterized clinically by proteinuria, microscopic hematuria, and hypertension that leads to end-stage renal failure in the second to fifth decade of life. Pathologic examination shows enlarged glomeruli with mesangial and subendothelial fibrillary deposits that show strong immunoreactivity to fibronectin (FN1 ) (Castelletti et al., 2008).
Clinical FeaturesTop most frequent phenotypes and symptoms related to Glomerulopathy With Fibronectin Deposits 1; Gfnd1
- Renal insufficiency
- Stage 5 chronic kidney disease
And another 15 symptoms. If you need more information about this disease we can help you.
Incidence and onset information— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.
Glomerulopathy With Fibronectin Deposits 1; Gfnd1 Is also known as glomerulopathy with giant fibrillar deposits, lobular glomerulopathy, familial.
Researches and researchersCurrently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.
Sources and references
You can check the following sources for additional information.OMIM Genetic Syndrome Finder
If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like MENTAL RETARDATION, X-LINKED 12; MRX12 ECTODERMAL DYSPLASIA 10B, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL RECESSIVE; ECTD10B CARNITINE PALMITOYLTRANSFERASE II DEFICIENCY, MYOPATHIC, STRESS-INDUCED KBG SYNDROME; KBGS CHARCOT-MARIE-TOOTH DISEASE, DOMINANT INTERMEDIATE B; CMTDIB AL KAISSI SYNDROME; ALKAS