Ghosal Hematodiaphyseal Dysplasia

Description

Ghosal hematodiaphyseal dysplasia syndrome (GHDD) is a rare disorder characterized by increased bone density (predominantly diaphyseal) and aregenerative corticosteroid-sensitive anemia.

Clinical Features

Top most frequent phenotypes and symptoms related to Ghosal Hematodiaphyseal Dysplasia

  • Pain
  • Anemia
  • Gait disturbance
  • Splenomegaly
  • Thrombocytopenia
  • Neurological speech impairment
  • Abnormal form of the vertebral bodies
  • Abnormality of the metaphysis
  • Bowing of the long bones
  • Increased bone mineral density

And another 14 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
No data available about the known clinical features onset.

Alternative names

Ghosal Hematodiaphyseal Dysplasia Is also known as ghosal syndrome, diaphyseal dysplasia-anemia syndrome.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.


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Ghosal Hematodiaphyseal Dysplasia Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Platelet Disorders.

By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University (United States).

RUNX1, STIM1, TBXA2R, TBXAS1, USF1, VPS33B, VWF, WAS, GP6, HPS3, HPS4, CD36, HPS5, DTNBP1, P2RY12, HPS6, MASTL, LYST, VIPAS39, FERMT3 , (...)

View the complete list with 34 more genes
Specificity
2 %
Genes
100 %
Bleeding Disorders Sequencing Panel with CNV Detection.

By PreventionGenetics PreventionGenetics (United States).

RUNX1, TBXA2R, TBXAS1, VWF, WAS, ADAMTS13, ABCG5, ABCG8, GP6, HPS3, HPS4, TUBB1, ACTN1, CD36, HPS5, DTNBP1, P2RY12, MCFD2, HPS6, MASTL , (...)

View the complete list with 41 more genes
Specificity
2 %
Genes
100 %
Platelet Function Disorder Sequencing Panel with CNV Detection.

By PreventionGenetics PreventionGenetics (United States).

TBXA2R, TBXAS1, GP6, HPS3, HPS4, CD36, HPS5, DTNBP1, P2RY12, HPS6, BLOC1S3, ANO6, GP1BA, GP1BB, GP9, HPS1, AP3B1, ITGA2, ITGA2B, ITGB3 , (...)

View the complete list with 2 more genes
Specificity
5 %
Genes
100 %
Skeletal Disorders and Joint Problems Sequencing Panel with CNV Detection.

By PreventionGenetics PreventionGenetics (United States).

RMRP, ROR2, RUNX2, SALL1, BMP1, BMP2, BMPR1B, SF3B4, SH3BP2, FBXW4, SHH, SHOX, SKI, SLCO2A1, SLC26A2, SMARCAL1, SMC1A, SOX9, SQSTM1, TBX15 , (...)

View the complete list with 236 more genes
Specificity
1 %
Genes
100 %
Dense bone dysplasia NGS panel.

By Connective Tissue Gene Tests (United States).

SLCO2A1, TBXAS1, TGFB1, TNFRSF11B, TYROBP, SOST, ANKH, DLX3, GJA1, HPGD, LRP4, MTAP, PTDSS1
Specificity
8 %
Genes
100 %
Dense bone dysplasia Comprehensive panel.

By Connective Tissue Gene Tests (United States).

SLCO2A1, TBXAS1, TGFB1, TNFRSF11B, TYROBP, SOST, ANKH, DLX3, GJA1, HPGD, LRP4, MTAP, PTDSS1
Specificity
8 %
Genes
100 %
Dense bone dysplasia Deletion / Duplication panel.

By Connective Tissue Gene Tests (United States).

SLCO2A1, TBXAS1, TGFB1, TNFRSF11B, TYROBP, SOST, ANKH, DLX3, GJA1, HPGD, LRP4, MTAP, PTDSS1
Specificity
8 %
Genes
100 %
Thrombocytopenia NGS Panel.

By Connective Tissue Gene Tests (United States).

RUNX1, SMPD1, SRC, TBXAS1, WAS, WIPF1, ADAMTS13, TUBB1, MASTL, LYST, CYCS, ANKRD26, NBEAL2, SLFN14, ETV6, MECOM, FLI1, FYB1, GATA1, GBA , (...)

View the complete list with 8 more genes
Specificity
4 %
Genes
100 %

We have 14 more panels available in our App

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Sources and references

You can check the following sources for additional information.

ORPHANET OMIM MESH Genetic Syndrome Finder

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