Familial Or Sporadic Hemiplegic Migraine
Description
Hemiplegic migraine (HM) is a rare variety of migraine with aura characterized by the presence of a motor weakness during the aura. Hemiplegic migraine has two main forms depending on the familial history: patients with at least one first- or second-degree relative who has aura including motor weakness have familial hemiplegic migraine (FHM); patients without such familial history have sporadic hemiplegic migraine (SHM).
Genes related to Familial Or Sporadic Hemiplegic Migraine
- CACNA1A
- ATP1A2
- PRRT2
- SCN1A
Clinical Features
Top most frequent phenotypes and symptoms related to Familial Or Sporadic Hemiplegic Migraine
- Seizures
- Ataxia
- Nystagmus
- Sensorineural hearing impairment
- Blindness
- Vomiting
- Headache
- Photophobia
- EEG abnormality
- Neurological speech impairment
And another 11 symptoms. If you need more information about this disease we can help you.
Incidence and onset information
— Based on the latest data available FAMILIAL OR SPORADIC HEMIPLEGIC MIGRAINE have a estimated prevalence of 10 per 100k worldwide.— No data available about the known clinical features onset.
Researches and researchers
Doctors, researchs, and experts related to Familial Or Sporadic Hemiplegic Migraine extracted from public data.
Familial Or Sporadic Hemiplegic Migraine Experts map
Current Researchs and researchers
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Clinical expert - Responsible for diagnostic tests - Investigator of research project - Coordinator of research network - Director of laboratoryMÜNCHEN — Pr Martin DICHGANS
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Institution/s:
— Neurologische Klinik und Poliklinik, LMU Klinikum der Universität München - Campus Großhadern
— Klinikum der Universität München -
Research area/topic::
Genetics of familial and sporadic hemiplegic migraine (Investigations on CACNA1A, ATP1A2 und SCN1A genes)
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Institution/s:
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Investigator of research projectTÜBINGEN — Dr Tobias FREILINGER
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Institution/s:
— Zentrum für Neurologie, Hertie-Institut für klinische Hirnforschung (HIH) -
Research area/topic::
Genetics of familial and sporadic hemiplegic migraine (Investigations on CACNA1A, ATP1A2 und SCN1A genes)
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Institution/s:
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Investigator of research projectMILANO — Dr Maria Pia ABBRACCHIO
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Institution/s:
— Università degli Studi di Milano - Scienze Farmacologiche e Biomolecolari -
Research area/topic::
Genetic and micro-environmental factors regulate the role of atp as transmitter of pain in a migraine model
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Institution/s:
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Investigator of research projectPADOVA — Pr Daniela PIETROBON
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Institution/s:
— Università degli Studi di Padova- Polo A.Vallisneri -
Research area/topic::
Familial hemiplegic migraine mechanisms
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Institution/s:
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Investigator of research projectPORTO — Pr Isabel SILVEIRA
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Institution/s:
— Instituto de Biologia Molecular e Celular -
Research area/topic::
CACNA1A gene involvement in cognition and synaptic function in calcium channel disease.
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Institution/s:
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Responsible for diagnostic tests - Investigator of research projectPORTO — Dr Isabel ALONSO
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Institution/s:
— Instituto de Biologia Molecular e Celular
— Instituto de Biologia Molecular e Celular -
Research area/topic::
Search for disease modifiers in spinocerebellar ataxias: human and animal-based approaches.
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Institution/s:
Familial Or Sporadic Hemiplegic Migraine Recommended genes panels
Panel Name, Specifity and genes Tested/covered |
---|
![]() By Athena Diagnostics Inc (United States).
CACNA1A
Specificity
100 %
Genes
25 % |
![]() By Athena Diagnostics Inc (United States).
ATXN1, ATXN10, ATXN2, ATXN7, ATXN8OS, TBP, CACNA1A, ATXN3
Specificity
13 %
Genes
25 % |
![]() By Athena Diagnostics Inc (United States).
SLC1A3, CACNA1A, CACNB4, KCNA1
Specificity
25 %
Genes
25 % |
![]() By Athena Diagnostics Inc (United States).
SACS, ATXN1, ATXN10, ATXN2, ATXN7, ATXN8OS, SLC1A3, SPTBN2, TBP, TTPA, VAMP1, CACNA1A, CACNB4, APTX, TGM6, COQ8A, SYNE1, TDP1, TTBK2, SYT14 , (...)
View the complete list with 22 more genes
Specificity
3 %
Genes
25 % |
![]() By Athena Diagnostics Inc (United States).
SLC1A3, SPTBN2, VAMP1, CACNA1A, CACNB4, TGM6, TTBK2, AFG3L2, EEF2, FGF14, ITPR1, KCNA1, KCNC3, KCND3, PDYN, PRKCG
Specificity
7 %
Genes
25 % |
![]() By Athena Diagnostics Inc (United States).
ATXN1, ATXN10, ATXN2, ATXN7, ATXN8OS, SLC1A3, SPTBN2, TBP, VAMP1, CACNA1A, CACNB4, TGM6, TTBK2, ATN1, AFG3L2, EEF2, FGF14, ITPR1, KCNA1, KCNC3 , (...)
View the complete list with 5 more genes
Specificity
4 %
Genes
25 % |
![]() By Athena Diagnostics Inc (United States).
SCN1A, CACNA1A, ATP1A2
Specificity
100 %
Genes
75 % |
![]() By Athena Diagnostics Inc (United States).
CACNA1A
Specificity
100 %
Genes
25 % |
You can get up to 342 more panels with our dedicated tool
Learn moreSources and references
You can check the following sources for additional information.
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