Deafness, X-linked 4; Dfnx4
Description
X-linked deafness-4 is a nonsyndromic form of progressive hearing loss with postlingual onset. Affected males show earlier onset of hearing loss than affected females (summary by del Castillo et al., 1996).
Clinical Features
Phenotypes and symptoms related to Deafness, X-linked 4; Dfnx4
- Hearing impairment
- Sensorineural hearing impairment
- Muscle weakness
- Bilateral sensorineural hearing impairment
- Progressive hearing impairment
- High-frequency hearing impairment
- Moderate hearing impairment
Incidence and onset information
— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)— No data available about the known clinical features onset.
Alternative names
Deafness, X-linked 4; Dfnx4 Is also known as dfn6, deafness, x-linked 6, progressive, deafness, nonsyndromic sensorineural progressive 6.
Researches and researchers
Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.Deafness, X-linked 4; Dfnx4 Recommended genes panels
Panel Name, Specifity and genes Tested/covered |
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Hearing Loss Advanced Sequencing and CNV Evaluation.
By Athena Diagnostics Inc (United States).
BCS1L, ROR1, SALL1, SEMA3E, SIX1, SIX5, SLC12A1, SLC19A2, SLC22A4, SNAI2, SMPX, SOX10, TBX1, TCOF1, TECTA, TFAP2A, TIMM8A, TJP2, TMPRSS3, USH1C , (...)
View the complete list with 149 more genes
Specificity
1 %
Genes
100 % |
NGS Hearing Loss Panel.
By Greenwood Genetic Center Diagnostic Laboratories Greenwood Genetic Center (United States).
SIX1, SNAI2, SMPX, SOX10, TECTA, TIMM8A, TJP2, TMPRSS3, USH1C, USH2A, CLRN1, TSPEAR, WFS1, ESPN, CDH23, CACNA1D, ACTG1, PCDH15, USH1G, WHRN , (...)
View the complete list with 70 more genes
Specificity
2 %
Genes
100 % |
OtoSCOPE.
By Molecular Otolaryngology and Renal Research Laboratories University of Iowa Hospital and Clinics (United States).
ROR1, SIX1, SIX5, SLC22A4, SNAI2, SMPX, SOX10, TBX1, TWNK, TCOF1, TECTA, TIMM8A, TJP2, TMPRSS3, USH1C, USH2A, CLRN1, TSPEAR, WFS1, ESPN , (...)
View the complete list with 130 more genes
Specificity
1 %
Genes
100 % |
Hearing Loss Panel.
By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University (United States).
RPS6KA3, SALL1, SEMA3E, SIX1, SIX5, SLC19A2, SNAI2, SMPX, SOX10, BTD, TCOF1, TECTA, TIMM8A, TJP2, TMPRSS3, USH1C, USH2A, CLRN1, WFS1, ESPN , (...)
View the complete list with 100 more genes
Specificity
1 %
Genes
100 % |
OtoGenome Test for Hearing Loss (110 Genes).
By Laboratory for Molecular Medicine Partners HealthCare Personalized Medicine (United States).
BCS1L, SIX1, SNAI2, SMPX, SOX10, TECTA, TIMM8A, TMPRSS3, USH1C, USH2A, CLRN1, WFS1, ESPN, CLIC5, CDH23, CABP2, RIPOR2, CACNA1D, ACTG1, PCDH15 , (...)
View the complete list with 89 more genes
Specificity
1 %
Genes
100 % |
Expanded Hearing Loss Panel, Sequencing and Deletion/Duplication.
By ARUP Laboratories, Molecular Genetics and Genomics (United States).
SMPX, TECTA, TMPRSS3, USH1C, USH2A, CLRN1, WFS1, ESPN, CDH23, ACTG1, PCDH15, STRC, USH1G, WHRN, OTOA, TMC1, TRIOBP, ADGRV1, CCDC50, CLDN14 , (...)
View the complete list with 35 more genes
Specificity
2 %
Genes
100 % |
Audiome (hearing loss panel).
By Division of Genomic Diagnostics The Children's Hospital of Philadelphia (United States).
BCS1L, SIX1, SNAI2, SMPX, SOX10, SUCLA2, TECTA, TIMM8A, TMPRSS3, USH1C, USH2A, CLRN1, TSPEAR, WFS1, ESPN, CLIC5, CDH23, CABP2, PCDH15, OSBPL2 , (...)
View the complete list with 85 more genes
Specificity
1 %
Genes
100 % |
Deafness, X-linked 4 (sequence analysis of SMPX gene).
By CGC Genetics (Portugal).
SMPX
Specificity
100 %
Genes
100 % |
You can get up to 21 more panels with our dedicated tool
Learn moreSources and references
You can check the following sources for additional information.
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