Cryptorchidism, Unilateral Or Bilateral

Table of contents:

Description
Related genes
Clinical Features
Incidence and onset information
Alternative Names
Researches and researchers
Gene Panels
Sources and references

Description

Cryptorchidism, or failure of testicular descent, is a common human congenital abnormality with a multifactorial etiology that likely reflects the involvement of endocrine, environmental, and hereditary factors. Cryptorchidism can result in infertility and increases risk for testicular tumors. Testicular descent from abdomen to scrotum occurs in 2 distinct phases: the transabdominal phase and the inguinoscrotal phase (summary by Gorlov et al., 2002).

Genes related to Cryptorchidism, Unilateral Or Bilateral

INSL3

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Clinical Features

Phenotypes and symptoms related to Cryptorchidism, Unilateral Or Bilateral

Cryptorchidism
Hypogonadism
Abnormality of the kidney
Infertility
Renal agenesis
Azoospermia
Bilateral cryptorchidism
Unilateral cryptorchidism
Delayed menarche

Incidence and onset information

— Not enough data available about incidence and published cases.
— No data available about the known clinical features onset.

Alternative names

Cryptorchidism, Unilateral Or Bilateral Is also known as undescended testis.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

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Cryptorchidism, Unilateral Or Bilateral Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Male Infertility Sequencing Panel with CNV Detection. By PreventionGenetics PreventionGenetics (United States). SEMA3A, SEMA3E, FOXL2, BRDT, SOX10, SOX2, SOX3, SOX9, SRA1, SRD5A2, SRY, STAR, AURKC, TAC3, TACR3, TAF4B, TEX11, WNT4, WT1, WWOX , (...) View the complete list with 87 more genes Panel 0 complete gene list SEMA3A, SEMA3E, FOXL2, BRDT, SOX10, SOX2, SOX3, SOX9, SRA1, SRD5A2, SRY, STAR, AURKC, TAC3, TACR3, TAF4B, TEX11, WNT4, WT1, WWOX, ARL6, WDR11, SLC26A8, CBX2, SPRY4, PROKR2, SUN5, TRIM32, CATSPER1, IL17RD, ARX, SYCP3, PROK2, BBS7, KLHL10, CFTR, PLCZ1, TTC8, CHD7, ZMYND15, RSPO1, GALNTL5, LHX4, FEZF1, NANOS1, CFAP44, MAMLD1, CYP11A1, CYP17A1, CYP19A1, BBS10, SEPT12, BBS12, CFAP43, CCDC141, DHH, SYCE1, DMRT1, DMRT2, DNAH1, NSMF, SPATA16, BBS9, DUSP6, AIRE, FGF17, FGF8, FGFR1, FGFR2, FLRT3, AKR1C4, FSHB, GATA4, GNRH1, GNRHR, KISS1R, ADGRG2, AMH, AMHR2, HESX1, HFE, HS6ST1, HSD17B3, INSL3, ANOS1, KISS1, AR, LEP, LEPR, LHB, LHCGR, LHX3, MAP3K1, MKKS, NPAS2, NR0B1, NR5A1, PCSK1, ATRX, AXL, POR, PICK1, PROP1, BBS1, BBS2, BBS4, BBS5 Specificity 1 % Genes 100 %
Disorders of Sex Development (DSD) and Infertility Sequencing Panel with CNV Detection. By PreventionGenetics PreventionGenetics (United States). ROR2, SALL1, BMP15, BMP4, SEMA3A, SEMA3E, BMP7, FOXL2, BRDT, SOS1, SOX10, SOX2, SOX3, SOX9, SRA1, SRD5A2, SRY, STAG3, STAR, AURKC , (...) View the complete list with 187 more genes Panel 1 complete gene list ROR2, SALL1, BMP15, BMP4, SEMA3A, SEMA3E, BMP7, FOXL2, BRDT, SOS1, SOX10, SOX2, SOX3, SOX9, SRA1, SRD5A2, SRY, STAG3, STAR, AURKC, TAC3, TACR3, TAF4B, TBX15, HNF1B, TEX11, MED12, CEP41, TSPYL1, WNT4, WNT5A, WNT7A, WT1, WWOX, ZP1, ARL6, FBXL4, WDR11, SLC26A8, ZEB2, CBX2, SPRY4, SETBP1, PROKR2, TOE1, TP63, PCNT, MCM8, SUN5, TRIM32, ZFPM2, UBR1, FIG4, CATSPER1, IL17RD, CDKN1C, PSMC3IP, ARX, SYCP3, HHAT, PROK2, GRIP1, BBS7, KLHL10, CFTR, FRAS1, CHD4, PLCZ1, EVC2, TTC8, HFM1, B3GLCT, PADI6, CHD7, TWIST2, CLPP, BCOR, ZMYND15, CUL7, ICK, MCM9, RSPO1, GALNTL5, LHX4, WDR60, NOBOX, FEZF1, NANOS1, FAT4, CREBBP, FIGLA, FREM2, CFAP44, MAMLD1, CYB5A, CYP11A1, CYP11B1, CYP17A1, CYP19A1, TMEM70, BBS10, SEPT12, BBS12, CFAP43, CCDC141, ESCO2, SOHLH1, CCNQ, DHCR24, DHCR7, DHH, SYCE1, SPECC1L, WDR35, EPG5, DMRT1, DMRT2, DNAH1, DYNC2H1, DNMT3B, NSMF, NUP107, SPATA16, BBS9, DUSP6, TRAIP, BNC2, EFNB1, EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5, EVC, AIRE, FGF10, FGF17, FGF8, FGFR1, FGFR2, FGFR3, FLNA, FLRT3, AKR1C4, FSHB, FSHR, GALT, GATA4, GLI3, GNRH1, GNRHR, GPC3, KISS1R, ADGRG2, AMH, AMHR2, HBA1, HCCS, HESX1, HFE, RIPK4, HOXA13, HOXA4, HOXB6, HS6ST1, HSD17B3, HSD17B4, HSD3B2, INSL3, IRF6, ANOS1, KISS1, AR, LEP, LEPR, LHB, LHCGR, LHX3, LMNA, MAP3K1, MID1, MKKS, MKS1, NEK1, ATF3, NPAS2, NR0B1, NR3C1, NR5A1, OPHN1, PCSK1, PDE4D, PEX1, ATRX, PITX2, AXL, POR, PICK1, PRLR, PROP1, PTDSS1, PTPN11, BBS1, BBS2, BBS4, BBS5, RBBP8 Specificity 1 % Genes 100 %
Disorders of Sex Development (DSD) Sequencing Panel with CNV Detection. By PreventionGenetics PreventionGenetics (United States). ROR2, SALL1, BMP15, BMP4, SEMA3A, BMP7, FOXL2, SOS1, SOX10, SOX2, SOX3, SOX9, SRD5A2, SRY, STAR, TAC3, TACR3, TBX15, HNF1B, MED12 , (...) View the complete list with 138 more genes Panel 2 complete gene list ROR2, SALL1, BMP15, BMP4, SEMA3A, BMP7, FOXL2, SOS1, SOX10, SOX2, SOX3, SOX9, SRD5A2, SRY, STAR, TAC3, TACR3, TBX15, HNF1B, MED12, CEP41, TSPYL1, WNT4, WNT5A, WNT7A, WT1, WWOX, ARL6, FBXL4, WDR11, ZEB2, CBX2, SETBP1, PROKR2, TOE1, TP63, PCNT, TRIM32, ZFPM2, UBR1, FIG4, IL17RD, CDKN1C, PSMC3IP, ARX, HHAT, PROK2, GRIP1, BBS7, FRAS1, CHD4, EVC2, TTC8, B3GLCT, CHD7, TWIST2, BCOR, CUL7, ICK, MCM9, RSPO1, LHX4, WDR60, FEZF1, FAT4, CREBBP, FREM2, MAMLD1, CYB5A, CYP11A1, CYP11B1, CYP17A1, CYP19A1, TMEM70, BBS10, BBS12, ESCO2, CCNQ, DHCR24, DHCR7, DHH, SPECC1L, WDR35, EPG5, DMRT1, DMRT2, DYNC2H1, DNMT3B, NSMF, BBS9, TRAIP, BNC2, EFNB1, EVC, FGF10, FGF8, FGFR1, FGFR2, FGFR3, FLNA, AKR1C4, FSHB, FSHR, GATA4, GLI3, GNRH1, GNRHR, GPC3, KISS1R, AMH, AMHR2, HBA1, HCCS, HESX1, HFE, RIPK4, HOXA13, HOXA4, HOXB6, HS6ST1, HSD17B3, HSD17B4, HSD3B2, INSL3, IRF6, ANOS1, KISS1, AR, LEP, LEPR, LHB, LHCGR, LHX3, LMNA, MAP3K1, MID1, MKKS, MKS1, NEK1, ATF3, NR0B1, NR3C1, NR5A1, OPHN1, PCSK1, PDE4D, PEX1, ATRX, PITX2, POR, PROP1, PTDSS1, PTPN11, BBS1, BBS2, BBS4, BBS5, RBBP8 Specificity 1 % Genes 100 %
Male Factor Infertility. By Asper Biogene Asper Biogene LLC (Estonia). TEKT2, XIST, USP26, PRDM9, RXFP2, RBMXL2, DDX25, CFTR, UTP14C, NLRP14, DNAH11, DNAH5, DNAI1, ESR2, FMR1, FSHB, GNRHR, INSL3, PRM1, PRM2 Specificity 5 % Genes 100 %
INSL3. By Fulgent Genetics Fulgent Genetics (United States). INSL3 Specificity 100 % Genes 100 %