Corneal Dystrophy, Fuchs Endothelial, 8; Fecd8
Fuchs endothelial corneal dystrophy (FECD) is the most common genetic disorder of the corneal endothelium. Late-onset FECD is marked by thickening of Descemets membrane and excrescences, called guttae, that typically appear in the fourth or fifth decade. Disease progression results in decreased visual acuity as a result of increasing corneal edema, and end-stage disease is marked by painful epithelial bullae (summary by Riazuddin et al., 2013).For a discussion of genetic heterogeneity of FECD, see FECD1 (OMIM ).
Genes related to Corneal Dystrophy, Fuchs Endothelial, 8; Fecd8
Clinical FeaturesPhenotypes and symptoms related to Corneal Dystrophy, Fuchs Endothelial, 8; Fecd8
- Reduced visual acuity
- Corneal dystrophy
Incidence and onset information— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.
Researches and researchersCurrently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.
Corneal Dystrophy, Fuchs Endothelial, 8; Fecd8 Recommended genes panels
|Panel Name, Specifity and genes Tested/covered|
Corneal Dystrophies Sequencing Panel with CNV Detection.
By PreventionGenetics PreventionGenetics (United States).
TACSTD2, TCF4, ZEB1, TGFBI, VSX1, OVOL2, SLC4A11, COL8A2, CYP4V2, ZNF469, PIKFYVE, AGBL1, LOXHD1, DCN, CHRDL1, UBIAD1, FOXE3, GJA8, GSN, KERA , (...)
View the complete list with 6 more genes
Eye Diseases - panels.
By MGZ Medical Genetics Center (Germany).
BFSP1, BFSP2, SALL2, BMP4, BMP7, SHH, SIX3, SIX6, FOXL2, SOX2, TACSTD2, ZEB1, TFAP2A, TGFBI, TGIF1, TREX1, TYR, TYRP1, VAX1, VIM , (...)
View the complete list with 146 more genes
By Fulgent Genetics Fulgent Genetics (United States).
You can get up to -5 more panels with our dedicated toolLearn more
Sources and references
You can check the following sources for additional information.OMIM Genetic Syndrome Finder
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