Congenital Lipomatous Overgrowth, Vascular Malformations, And Epidermal Nevi

Description

CLOVE syndrome is characterized by Congenital Lipomatous Overgrowth, progressive, complex and mixed truncal Vascular malformations, and Epidermal nevi.

Clinical Features

Top most frequent phenotypes and symptoms related to Congenital Lipomatous Overgrowth, Vascular Malformations, And Epidermal Nevi

  • Seizures
  • Scoliosis
  • Nystagmus
  • Ptosis
  • Cataract
  • Nevus
  • Splenomegaly
  • Agenesis of corpus callosum
  • Constipation
  • Hypoglycemia
And another 30 symptoms. If you need more information about this disease we can help you.
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Incidence and onset information

Not enough data available about incidence and published cases.


Mendelian

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Congenital Lipomatous Overgrowth, Vascular Malformations, And Epidermal Nevi Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Comprehensive Brain Malformation Panel.

By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University in United States.

UBE3A, PTEN, TUBB3, CC2D2A, OTX2, TMEM67, NPHP1, CEP290, SHH, SLC25A19, MECP2, TUBA1A, RARS2, MRPS16, SLC9A6, MKS1, SOX2, HESX1, ARX, CDKL5 , (...)

View the complete list with 86 more genes
Specificity
1 %
Genes
100 %
Macrocephaly.

By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University in United States.

PTEN, NSD1, PTCH1, PHF6, CUL4B, MED12, UPF3B, NFIX, EZH2, GLI3, PIK3CA
Specificity
10 %
Genes
100 %
PIK3CA sequence analysis (Somatic).

By Genetic Diagnostic Laboratory University of Pennsylvania School of Medicine in United States.

PIK3CA
Specificity
100 %
Genes
100 %
Somatic Overgrowth Gene Panel.

By Genetic Diagnostic Laboratory University of Pennsylvania School of Medicine in United States.

MTOR, PIK3CA, AKT2, GNAQ, GNA11, PIK3R2, AKT3, AKT1
Specificity
13 %
Genes
100 %
PIK3CA Sequencing.

By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center in United States.

PIK3CA
Specificity
100 %
Genes
100 %
Hereditary Thyroid Cancer Panel.

By Genetic Services Laboratory University of Chicago in United States.

APC, PTEN, TP53, RET, SDHB, SDHD, CHEK2, PRKAR1A, PIK3CA, AKT1, WRN, SRGAP1, DICER1
Specificity
8 %
Genes
100 %
PIK3CA.

By Institute for Human Genetics University Clinic Freiburg in Germany.

PIK3CA
Specificity
100 %
Genes
100 %
Vascular Malformations NGS Multi-Gene Panel (21 Genes).

By Laboratory of genome diagnostics Academic Medical Center, University of Amsterdam in Netherlands.

PTEN, SMAD4, ENG, KRIT1, CCM2, PDCD10, RASA1, SOX18, ACVRL1, GDF2, KCNK3, CAV1, BMPR2, GLMN, TEK, PIK3CA, GNAQ, KDR, MAP3K3, DOCK6 , (...)

View the complete list with 1 more genes
Specificity
5 %
Genes
100 %
Segmental Overgrowth Disorders - NGS panel (8 genes).

By Laboratory of genome diagnostics Academic Medical Center, University of Amsterdam in Netherlands.

PTEN, TSC2, TSC1, MTOR, PIK3CA, PIK3R2, AKT3, AKT1
Specificity
13 %
Genes
100 %
PIK3CA. Complete sequencing.

By Instituto de Medicina Genomica Instituto de Medicina Genomica in Spain.

PIK3CA
Specificity
100 %
Genes
100 %
Macrocephaly (NGS panel for 16 genes).

By CGC Genetics in Portugal.

PTEN, ASPA, NSD1, GPC3, MLC1, PIGA, PIGN, GFAP, MED12, NFIX, EZH2, PIK3CA, DHCR24, PIK3R2, AKT3, HEPACAM
Specificity
7 %
Genes
100 %
Megalencephaly-polymicrogyria and dysplastic megalencephaly (NGS panel of 8 genes).

By CGC Genetics in Portugal.

DEPDC5, MTOR, EZH2, PIK3CA, PIK3R2, AKT3, CCND2, NPRL3
Specificity
13 %
Genes
100 %
Cowden syndrome type 5 (sequence analysis of PIK3CA gene).

By CGC Genetics in Portugal.

PIK3CA
Specificity
100 %
Genes
100 %
Megalencephaly-polymicrogyria and dysplastic megalencephaly (NGS panel of 8 genes).

By CGC Genetics in Portugal.

DEPDC5, MTOR, EZH2, PIK3CA, PIK3R2, AKT3, CCND2, NPRL3
Specificity
13 %
Genes
100 %
Cowden syndrome type 5 (sequence analysis of PIK3CA gene).

By CGC Genetics in Portugal.

PIK3CA
Specificity
100 %
Genes
100 %
Cowden and Cowden-like Syndromes via the PIK3CA Gene.

By PreventionGenetics PreventionGenetics in United States.

PIK3CA
Specificity
100 %
Genes
100 %
Mental retardation - different panels.

By Institute of Human Genetics Cologne University in Germany.

FMR1, UBE3A, PTEN, MCCC1, MCCC2, ACAD9, PC, ANKH, HLCS, ATP7A, AUH, B4GALT7, BCKDHA, BCKDHB, BCS1L, C12orf65, ADSL, MMACHC, PRKCG, PAX6 , (...)

View the complete list with 847 more genes
Specificity
1 %
Genes
100 %
Hereditary kidney disorders - different panels.

By Institute of Human Genetics Cologne University in Germany.

VHL, ACAT1, ARG1, ATP7B, AUH, BCS1L, INVS, HNF1A, MMACHC, EYA1, LRP5, SLC34A1, WT1, PAX6, SDHAF2, HNF1B, RET, INPP5E, CPS1, GLB1 , (...)

View the complete list with 391 more genes
Specificity
1 %
Genes
100 %
Colorectal adenocarcinoma, somatic mutation sequencing panel.

By Molecular Diagnostics Laboratory University Health Network in Canada.

BRAF, KRAS, NRAS, PIK3CA
Specificity
25 %
Genes
100 %
Custom solid tumor gene sequencing panel.

By Molecular Diagnostics Laboratory University Health Network in Canada.

APC, PTEN, TP53, FOXL2, TYRP1, RET, RAF1, BRAF, HRAS, KRAS, MAP2K1, NRAS, CDK4, CDKN2A, MET, NF1, GRIN2A, HGF, ERCC2, CTNNB1 , (...)

View the complete list with 25 more genes
Specificity
3 %
Genes
100 %
Macrocephaly.

By MGZ Medical Genetics Center in Germany.

PTEN, ASPA, TSC2, TSC1, NSD1, PTCH1, CDKN1C, GPC3, MLC1, EIF2B5, L1CAM, WASHC5, SETD2, OFD1, GRIA3, SYN1, CUL4B, RAB39B, GFAP, MED12 , (...)

View the complete list with 22 more genes
Specificity
3 %
Genes
100 %
Mental Retardation and Dysmorphology - panels.

By MGZ Medical Genetics Center in Germany.

FMR1, UBE3A, PTEN, RECQL4, AGL, ATP7A, GAA, LRP5, SLC37A4, GNPTAB, GLB1, HSD17B10, OCRL, JAG1, NDP, HPRT1, NHS, RAF1, SMPD1, MECP2 , (...)

View the complete list with 323 more genes
Specificity
1 %
Genes
100 %
Syndromal Diseases - panels.

By MGZ Medical Genetics Center in Germany.

FMR1, UBE3A, PTEN, RECQL4, AGL, ATP7A, GAA, LRP5, SLC37A4, GNPTAB, GLB1, HSD17B10, OCRL, JAG1, NDP, HPRT1, NHS, RAF1, SMPD1, MECP2 , (...)

View the complete list with 322 more genes
Specificity
1 %
Genes
100 %
Brain Malformations / Neuronal Migration Disorders.

By MGZ Medical Genetics Center in Germany.

FMR1, UBE3A, PTEN, APP, TUBB3, HSD17B10, HPRT1, PANK2, FH, MECP2, GAMT, STXBP1, TUBA1A, SLC25A22, GLDC, GK, MAOA, ACSL4, SLC9A6, ALDH7A1 , (...)

View the complete list with 246 more genes
Specificity
1 %
Genes
100 %
Megalencephaly.

By MGZ Medical Genetics Center in Germany.

PTEN, TSC2, TSC1, PIK3CA, PIK3R2, AKT3, AKT1, CCND2
Specificity
13 %
Genes
100 %
Cancer Hotspot Panel.

By Centogene AG - the Rare Disease Company in Germany.

BRCA1, BRCA2, VHL, APC, MLH1, PTEN, TP53, HNF1A, RB1, RET, GNAT2, IDH2, FGFR3, AR, BRAF, HRAS, KRAS, NRAS, PTPN11, FGFR2 , (...)

View the complete list with 68 more genes
Specificity
2 %
Genes
100 %
Solid Tumor Panel.

By Centogene AG - the Rare Disease Company in Germany.

VHL, APC, MLH1, PTEN, TP53, RB1, RET, IDH2, FGFR3, AR, BRAF, HRAS, KRAS, MAP2K1, NRAS, PTPN11, FGFR2, TSC1, ALK, ATM , (...)

View the complete list with 42 more genes
Specificity
2 %
Genes
100 %
CLOVE syndrome.

By Centogene AG - the Rare Disease Company in Germany.

PIK3CA
Specificity
100 %
Genes
100 %
AllNeuro panel.

By Centogene AG - the Rare Disease Company in Germany.

F2, F5, FMR1, HTT, HFE, MTHFR, TTR, UBE3A, VHL, PTEN, AARS2, ABHD12, ACACA, ACAD9, ACADL, ACADM, ACADS, AGL, ACADVL, ACAT1 , (...)

View the complete list with 1185 more genes
Specificity
1 %
Genes
100 %
Disorders associated with malignancy Panel.

By CeGaT GmbH in Germany.

MSH2, PMS2, MSH6, MLH1, PTEN, RECQL4, SDHB, BLM, TINF2, TSC2, TSC1, ATM, PTCH1, NF2, STK11, SDHD, FLCN, PRKAR1A, RTEL1, NF1 , (...)

View the complete list with 25 more genes
Specificity
3 %
Genes
100 %
Familial Tumor Syndromes Panel.

By CeGaT GmbH in Germany.

PTEN, RECQL4, TP53, RB1, RET, SDHC, FH, SDHB, BLM, TSC2, TSC1, NBN, NF2, CDKN2A, SDHD, MET, CDC73, NF1, LZTR1, SPRED1 , (...)

View the complete list with 12 more genes
Specificity
4 %
Genes
100 %
Neuronal Migration Disorders Panel.

By CeGaT GmbH in Germany.

TUBB3, FH, TUBA1A, ARX, MEF2C, WDR62, FKTN, POMGNT1, FKRP, DYNC1H1, POMT2, POMT1, ISPD, LAMA2, B4GAT1, POMGNT2, RXYLT1, LARGE1, B3GALNT2, COL4A1 , (...)

View the complete list with 30 more genes
Specificity
2 %
Genes
100 %
RASopathies Panel.

By CeGaT GmbH in Germany.

RAF1, BRAF, HRAS, KRAS, MAP2K1, NRAS, PTPN11, SHOC2, SOS1, RIT1, MAP2K2, CBL, NF1, RASA1, SPRED1, RASA2, RRAS, A2ML1, STAMBP, PIK3CA , (...)

View the complete list with 3 more genes
Specificity
5 %
Genes
100 %
Macrocephaly Panel.

By CeGaT GmbH in Germany.

PTEN, GCDH, ASPA, NSD1, GPC3, MLC1, PIGA, PIGN, GFAP, MED12, NFIX, EZH2, PIK3CA, DHCR24, PIK3R2, AKT3, HEPACAM
Specificity
6 %
Genes
100 %
Neuronal Migration Disorders Panel.

By CeGaT GmbH in Germany.

TUBB3, FH, TUBA1A, ARX, MEF2C, WDR62, FKTN, POMGNT1, FKRP, DYNC1H1, POMT2, POMT1, ISPD, LAMA2, B4GAT1, POMGNT2, RXYLT1, LARGE1, B3GALNT2, COL4A1 , (...)

View the complete list with 30 more genes
Specificity
2 %
Genes
100 %
Macrocephaly Panel.

By CeGaT GmbH in Germany.

PTEN, GCDH, ASPA, NSD1, GPC3, MLC1, PIGA, PIGN, GFAP, MED12, NFIX, EZH2, PIK3CA, DHCR24, PIK3R2, AKT3, HEPACAM
Specificity
6 %
Genes
100 %
RASopathies Panel.

By CeGaT GmbH in Germany.

RAF1, BRAF, HRAS, KRAS, MAP2K1, NRAS, PTPN11, SHOC2, SOS1, RIT1, MAP2K2, CBL, NF1, RASA1, SPRED1, RASA2, RRAS, A2ML1, STAMBP, PIK3CA , (...)

View the complete list with 3 more genes
Specificity
5 %
Genes
100 %
RASopathies Panel.

By CeGaT GmbH in Germany.

RAF1, BRAF, HRAS, KRAS, MAP2K1, NRAS, PTPN11, SHOC2, SOS1, RIT1, MAP2K2, CBL, NF1, RASA1, SPRED1, RASA2, RRAS, A2ML1, STAMBP, PIK3CA , (...)

View the complete list with 3 more genes
Specificity
5 %
Genes
100 %
CLOVE syndrome, somatic (PIK3CA).

By MVZ Dortmund Dr. Eberhard & Partner in Germany.

PIK3CA
Specificity
100 %
Genes
100 %
PIK3CA-Related Segmental Overgrowth (Cowden Syndrome 5): PIK3CA gene sequence analysis.

By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases in Spain.

PIK3CA
Specificity
100 %
Genes
100 %
NOONAN, LEOPARD, COSTELLO and CARDIOFACIOCUTANEOUS SYNDROME.

By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases in Spain.

PRKCG, RAF1, IL2RG, FGFR3, BRAF, HRAS, KRAS, MAP2K1, NRAS, PTPN11, SHOC2, SOS1, RIT1, MAP2K2, CBL, MET, NF1, SHOX, ANKRD11, SPRED1 , (...)

View the complete list with 24 more genes
Specificity
3 %
Genes
100 %
Melanoma: Sequencing Panel.

By EGL Genetic Diagnostics Eurofins Clinical Diagnostics in United States.

PTEN, RB1, BRAF, KRAS, MAP2K1, NRAS, CDK4, CDKN2A, KIT, BAP1, PIK3CA, GNAQ, WRN
Specificity
8 %
Genes
100 %
PIK3CA.

By Fulgent Genetics Fulgent Genetics in United States.

PIK3CA
Specificity
100 %
Genes
100 %
Hemato-oncology chromosomal microarray.

By Pittsburgh Cytogenetics Laboratory University of Pittsburgh Medical Center in United States.

BRCA1, BRCA2, APC, MSH2, MLH1, TP53, COL1A1, RB1, BLM, BRAF, HRAS, ALK, PTCH1, PHOX2B, SUFU, CDH1, FUS, SETD2, KDM5C, PAX3 , (...)

View the complete list with 72 more genes
Specificity
2 %
Genes
100 %
Macrocephaly / Overgrowth Syndrome Panel.

By Blueprint Genetics in Finland.

PTEN, ASPA, TSC2, TSC1, NSD1, PTCH1, CDKN1C, GPC3, MLC1, EIF2B5, L1CAM, WASHC5, SETD2, PIGA, OFD1, GRIA3, SYN1, CUL4B, RAB39B, GFAP , (...)

View the complete list with 23 more genes
Specificity
3 %
Genes
100 %
Neuronal Migration Disorder Panel.

By Blueprint Genetics in Finland.

TUBB3, ATP6V0A2, FH, TUBA1A, ARX, MEF2C, WDR62, FKTN, PHGDH, L1CAM, DYNC1H1, POMT1, ISPD, LAMA2, POMGNT2, RXYLT1, LARGE1, B3GALNT2, COL4A1, ARFGEF2 , (...)

View the complete list with 38 more genes
Specificity
2 %
Genes
100 %
Comprehensive Skeletal Dysplasias and Disorders Panel.

By Blueprint Genetics in Finland.

RECQL4, ALPL, ANKH, TYROBP, FKBP10, B4GALT7, LRP5, COL2A1, COL1A1, COL1A2, SOST, TGFB1, LEMD3, TNFRSF11A, PYCR1, CLCN7, ATP6V0A2, FBN1, SERPINF1, SP7 , (...)

View the complete list with 226 more genes
Specificity
1 %
Genes
100 %
Lymphatic Malformations and Related Disorders Panel.

By Blueprint Genetics in Finland.

GJC2, GATA2, FOXC2, PIEZO1, FAT4, RASA1, SOX18, CCBE1, KIF11, FLT4, PIK3CA
Specificity
10 %
Genes
100 %
Vascular Malformations Panel.

By Blueprint Genetics in Finland.

PTEN, SMAD4, ENG, KRIT1, CCM2, PDCD10, RASA1, SOX18, ACVRL1, GLMN, STAMBP, TEK, PIK3CA, ELMO2
Specificity
8 %
Genes
100 %
Comprehensive Growth Disorders / Skeletal Dysplasias and Disorders Panel.

By Blueprint Genetics in Finland.

RECQL4, ALPL, ANKH, TYROBP, FKBP10, B4GALT7, BCS1L, IFITM5, LRP5, COL2A1, COL1A1, COL1A2, COL3A1, SOST, TGFB1, LEMD3, TNFRSF11A, PYCR1, CLCN7, ATP6V0A2 , (...)

View the complete list with 288 more genes
Specificity
1 %
Genes
100 %
PIK3CA Mutation by Sequencing.

By Cancer Genetics, Inc. Cancer Genetics, Inc. in United States.

PIK3CA
Specificity
100 %
Genes
100 %
Liquid::Lung-cfDNA™ NGS Panel.

By Cancer Genetics, Inc. Cancer Genetics, Inc. in United States.

TP53, BRAF, KRAS, MAP2K1, NRAS, ALK, MET, PIK3CA, EGFR, ERBB2, ROS1
Specificity
10 %
Genes
100 %
Focus::Oncomine™ NGS Panel.

By Cancer Genetics, Inc. Cancer Genetics, Inc. in United States.

RET, RAF1, IDH2, FGFR3, AR, BRAF, HRAS, KRAS, MAP2K1, NRAS, FGFR2, MAP2K2, ALK, CDK4, MET, CTNNB1, MTOR, ERBB3, KIT, JAK3 , (...)

View the complete list with 15 more genes
Specificity
3 %
Genes
100 %
Focus::Renal® NGS Panel.

By Cancer Genetics, Inc. Cancer Genetics, Inc. in United States.

VHL, PTEN, TP53, RAF1, BRAF, TSC2, TSC1, ALK, PTCH1, MET, FGFR1, SETD2, KDM5C, MTOR, ARID1A, KIT, BAP1, PIK3CA, AKT2, FLT3 , (...)

View the complete list with 12 more genes
Specificity
4 %
Genes
100 %
Somatic Overgrowth Gene Set.

By Genomics and Pathology Services Washington University in St. Louis in United States.

PTEN, IDH2, TSC2, TSC1, RASA1, MTOR, PIK3CA, AKT2, GNAQ, IDH1, GNA11, PIK3R2, AKT3, AKT1, SMO
Specificity
7 %
Genes
100 %
Solid Tumor Gene Set.

By Genomics and Pathology Services Washington University in St. Louis in United States.

BRCA1, BRCA2, VHL, APC, MLH1, PTEN, TP53, FOXL2, PPARG, WT1, RB1, RET, RAF1, IDH2, FGFR3, AR, BRAF, CREBBP, HRAS, KRAS , (...)

View the complete list with 102 more genes
Specificity
1 %
Genes
100 %
PIK3CA-Related Overgrowth Gene Set.

By Genomics and Pathology Services Washington University in St. Louis in United States.

PIK3CA
Specificity
100 %
Genes
100 %
Nevus Gene Set.

By Genomics and Pathology Services Washington University in St. Louis in United States.

FGFR3, HRAS, KRAS, NRAS, PIK3CA, GNAQ, GNA11
Specificity
15 %
Genes
100 %
CNS Tumor Gene Set.

By Genomics and Pathology Services Washington University in St. Louis in United States.

PTEN, TP53, WT1, RB1, SHH, IDH2, BRAF, KRAS, FGFR2, PTCH1, NF2, SUFU, CDKN2A, MET, NTRK1, NF1, FGFR1, SETD2, ATRX, MED12 , (...)

View the complete list with 28 more genes
Specificity
3 %
Genes
100 %
Melanoma Gene Set.

By Genomics and Pathology Services Washington University in St. Louis in United States.

PTEN, TP53, RB1, RET, FGFR3, BRAF, HRAS, KRAS, MAP2K1, NRAS, FGFR2, MAP2K2, ALK, CDK4, CDKN2A, MET, NF1, FGFR1, KMT2D, MED12 , (...)

View the complete list with 18 more genes
Specificity
3 %
Genes
100 %
Breast Tumors Gene Set.

By Genomics and Pathology Services Washington University in St. Louis in United States.

BRCA1, BRCA2, PTEN, RUNX1, TP53, RB1, RET, IDH2, BRAF, HRAS, KRAS, MAP2K1, FGFR2, MAP2K2, ATM, PALB2, CDH1, STK11, CDK4, CDKN2A , (...)

View the complete list with 22 more genes
Specificity
3 %
Genes
100 %
Genitourinary Tumors Gene Set.

By Genomics and Pathology Services Washington University in St. Louis in United States.

BRCA1, BRCA2, VHL, MLH1, PTEN, TP53, PPARG, FGFR3, AR, BRAF, CREBBP, HRAS, NRAS, FGFR2, TSC2, TSC1, ATM, PTCH1, CDKN2A, MET , (...)

View the complete list with 24 more genes
Specificity
3 %
Genes
100 %
Gynecologic Tumors Gene Set.

By Genomics and Pathology Services Washington University in St. Louis in United States.

BRCA1, BRCA2, VHL, APC, MLH1, PTEN, TP53, FOXL2, RB1, BCOR, FGFR3, BRAF, HRAS, KRAS, MAP2K1, NRAS, FGFR2, MAP2K2, ATM, STK11 , (...)

View the complete list with 30 more genes
Specificity
2 %
Genes
100 %
Head & Neck Tumors Gene Set.

By Genomics and Pathology Services Washington University in St. Louis in United States.

BRCA1, BRCA2, APC, PTEN, TP53, RB1, HRAS, KRAS, NRAS, NSD1, ATM, CDKN2A, SMAD4, NF1, KMT2D, MTOR, NOTCH1, TGFBR2, KDM6A, EP300 , (...)

View the complete list with 21 more genes
Specificity
3 %
Genes
100 %
Cowden Syndrome NGS and Deletion/Duplication Panel.

By DDC Clinic Molecular Diagnostics Laboratory DDC Clinic, Center for Special Needs Children in United States.

PTEN, SDHB, SDHD, PIK3CA, AKT1
Specificity
20 %
Genes
100 %
PIK3CA Gene Sequencing and Deletion/Duplication Analysis.

By DDC Clinic Molecular Diagnostics Laboratory DDC Clinic, Center for Special Needs Children in United States.

PIK3CA
Specificity
100 %
Genes
100 %
FoundationOne® Heme.

By Foundation Medicine, Inc. in United States.

BRCA1, BRCA2, VHL, APC, MSH2, MSH6, MLH1, MUTYH, PTEN, RUNX1, TP53, PC, FOXL2, HNF1A, WT1, RB1, RET, TNFRSF11A, CPS1, SDHC , (...)

View the complete list with 385 more genes
Specificity
1 %
Genes
100 %
Guardant360.

By Guardant Health in United States.

BRCA1, BRCA2, VHL, APC, MLH1, PTEN, TP53, HNF1A, RB1, RET, RAF1, IDH2, FGFR3, AR, BRAF, HRAS, KRAS, MAP2K1, NRAS, PTPN11 , (...)

View the complete list with 53 more genes
Specificity
2 %
Genes
100 %
Comprehensive Panel for Individualized Cancer Threatment.

By GeneKor MSA in Greece.

VHL, APC, PTEN, TP53, HNF1A, RB1, RET, IDH2, FGFR3, BRAF, HRAS, KRAS, MAP2K1, NRAS, PTPN11, FGFR2, ALK, ATM, CDH1, CDKN2A , (...)

View the complete list with 32 more genes
Specificity
2 %
Genes
100 %
Cancer Hotspot Analysis.

By Advanced Technology Laboratory Spectrum Health in United States.

VHL, APC, MLH1, PTEN, TP53, HNF1A, RB1, RET, IDH2, FGFR3, BRAF, HRAS, KRAS, NRAS, PTPN11, FGFR2, ALK, ATM, CDH1, STK11 , (...)

View the complete list with 30 more genes
Specificity
2 %
Genes
100 %
Circulo Colorectal.

By Circulogene Theranostics in United States.

PIK3CA
Specificity
100 %
Genes
100 %
Circulo Lung.

By Circulogene Theranostics in United States.

PIK3CA
Specificity
100 %
Genes
100 %
Circulo Breast.

By Circulogene Theranostics in United States.

PIK3CA
Specificity
100 %
Genes
100 %
Circulo Melanoma.

By Circulogene Theranostics in United States.

PIK3CA
Specificity
100 %
Genes
100 %
Circulo Gastric.

By Circulogene Theranostics in United States.

PIK3CA
Specificity
100 %
Genes
100 %
Circulo Ovarian.

By Circulogene Theranostics in United States.

PIK3CA
Specificity
100 %
Genes
100 %
Hereditary Cancer Comprehensive Panel.

By NeoGenomics Laboratories NeoGenomics Laboratories, Inc. in United States.

BRCA1, BRCA2, VHL, APC, EPCAM, MSH2, PMS2, MSH6, MLH1, MUTYH, PTEN, RUNX1, TP53, WT1, RET, SDHC, SDHB, MEN1, ATM, MRE11 , (...)

View the complete list with 53 more genes
Specificity
2 %
Genes
100 %
NeoTYPE® Discovery Profile for Solid Tumors.

By NeoGenomics Laboratories NeoGenomics Laboratories, Inc. in United States.

BRCA1, BRCA2, VHL, APC, MSH2, PMS2, MSH6, MLH1, MUTYH, PTEN, RUNX1, TP53, FOXL2, HNF1A, WT1, RB1, RET, SDHC, RAF1, FH , (...)

View the complete list with 295 more genes
Specificity
1 %
Genes
100 %
Caris MI TumorSeek 592-Gene NGS Panel.

By Caris Life Sciences in United States.

BRCA1, BRCA2, VHL, APC, MSH2, PMS2, MSH6, MLH1, MUTYH, PTEN, RECQL4, RUNX1, TP53, FOXL2, HNF1A, PPARG, COL1A1, WT1, RB1, SDHAF2 , (...)

View the complete list with 571 more genes
Specificity
1 %
Genes
100 %
OmniSeq Comprehensive.

By OmniSeq, Inc. in United States.

BRCA1, BRCA2, VHL, APC, MSH2, MLH1, PTEN, TP53, FOXL2, HNF1A, PPARG, WT1, RB1, RET, RAF1, IDH2, SOX2, STAT3, PNP, FGFR3 , (...)

View the complete list with 124 more genes
Specificity
1 %
Genes
100 %
Solid Tumor Targeted Mutation and Fusion Panel.

By Providence Regional Laboratories Providence Health and Services in United States.

PPARG, RET, RAF1, IDH2, FGFR3, AR, BRAF, HRAS, KRAS, MAP2K1, NRAS, FGFR2, MAP2K2, ALK, CDK4, MET, NTRK1, FGFR1, CTNNB1, MTOR , (...)

View the complete list with 30 more genes
Specificity
2 %
Genes
100 %
Cowden Syndrome, Sequencing PIK3CA Gene.

By Reference Laboratory Genetics in Spain.

PIK3CA
Specificity
100 %
Genes
100 %
Megalencephaly-Capillary Malformation-Polymicrogyria Syndrome , Sequencing PIK3CA Gene.

By Reference Laboratory Genetics in Spain.

PIK3CA
Specificity
100 %
Genes
100 %
Macrocephaly , Panel Massive Sequencing (NGS) 16 Genes.

By Reference Laboratory Genetics in Spain.

PTEN, ASPA, NSD1, GPC3, MLC1, PIGA, PIGN, GFAP, MED12, NFIX, EZH2, PIK3CA, DHCR24, PIK3R2, AKT3, HEPACAM
Specificity
7 %
Genes
100 %
Malformations of Cortical Development , Panel Massive Sequencing (NGS) 38 Genes.

By Reference Laboratory Genetics in Spain.

TUBB3, TUBA1A, ARX, FOXG1, WDR62, FKTN, POMGNT1, FKRP, DYNC1H1, POMT2, POMT1, LAMA2, LARGE1, ASPM, COL4A1, ARFGEF2, DCX, NDE1, RELN, TUBA8 , (...)

View the complete list with 18 more genes
Specificity
3 %
Genes
100 %
Glioma (Susceptibility to Somatic) , Panel Massive Sequencing (NGS) 12 Genes.

By Reference Laboratory Genetics in Spain.

BRCA2, PTEN, TP53, RB1, IDH2, PRKN, BRAF, LGI1, PIK3CA, EGFR, IDH1, ERBB2
Specificity
9 %
Genes
100 %
152 Integrated Advantage NGS Solid Tumor Panel.

By Integrated Molecular Diagnostics Pathology, Inc. in United States.

BRCA1, BRCA2, MTHFR, VHL, APC, MLH1, PTEN, TP53, RB1, RET, RAF1, IDH2, TYMP, STAT3, FGFR3, AR, FANCC, BRAF, HRAS, KRAS , (...)

View the complete list with 132 more genes
Specificity
1 %
Genes
100 %
Tempus xT assay.

By Tempus Labs, Inc. in United States.

BRCA1, BRCA2, MTHFR, VHL, APC, EPCAM, MSH2, PMS2, MSH6, MLH1, MUTYH, PTEN, RECQL4, RUNX1, TP53, ATP7B, FOXL2, HNF1A, WT1, RB1 , (...)

View the complete list with 571 more genes
Specificity
1 %
Genes
100 %
Tempus xO assay.

By Tempus Labs, Inc. in United States.

BRCA1, BRCA2, VHL, APC, EPCAM, MSH2, PMS2, MSH6, MLH1, MUTYH, PTEN, RECQL4, RUNX1, TP53, ABCB11, ABCB4, FKBP10, FOXL2, HNF1A, PPARG , (...)

View the complete list with 1693 more genes
Specificity
1 %
Genes
100 %
CEN4GEN Comprehensive Hereditary Cancer Syndrome: Gene sequencing Panel.

By CEN4GEN Institute for Genomics and Molecular Diagnostics in Canada.

BRCA1, BRCA2, HFE, VHL, APC, EPCAM, MSH2, PMS2, MSH6, MLH1, MUTYH, PTEN, RECQL4, RUNX1, TP53, WT1, RB1, SDHAF2, RET, MC1R , (...)

View the complete list with 123 more genes
Specificity
1 %
Genes
100 %
CEN4GEN Breast cancer: Extended gene sequencing Panel.

By CEN4GEN Institute for Genomics and Molecular Diagnostics in Canada.

BRCA1, BRCA2, PTEN, TP53, RB1, RET, SEPT9, FGFR2, ATM, CDH1, CDKN2A, FGFR1, GATA3, NEK2, ERBB3, EP300, BAP1, PIK3CA, EGFR, AKT1 , (...)

View the complete list with 25 more genes
Specificity
3 %
Genes
100 %
CEN4GEN Colorectal cancer: Extended Sequencing Panel.

By CEN4GEN Institute for Genomics and Molecular Diagnostics in Canada.

APC, MSH2, MSH6, MLH1, TP53, CASP8, BRAF, DMD, KRAS, NRAS, ATM, SMAD4, CTNNB1, TGFBR2, SLC9A9, EP300, SMAD2, PIK3CA, FBXW7, AKT1 , (...)

View the complete list with 18 more genes
Specificity
3 %
Genes
100 %
CEN4GEN Gastric cancer: Extended gene sequencing Panel.

By CEN4GEN Institute for Genomics and Molecular Diagnostics in Canada.

BRCA2, APC, TP53, RET, FGFR2, CDH1, STK11, MET, LRRK2, S1PR2, CTNNB1, NOTCH1, SPEG, PIK3CA, FBXW7, PRKDC, ERBB2, MYC, DCC, TRIO , (...)

View the complete list with 9 more genes
Specificity
4 %
Genes
100 %
CEN4GEN Lung cancer: Extended gene sequencing Panel.

By CEN4GEN Institute for Genomics and Molecular Diagnostics in Canada.

APC, MLH1, PTEN, TP53, RB1, RET, SOX2, BRAF, KRAS, FGFR2, ALK, ATM, STK11, CDKN2A, MET, SMAD4, PKHD1, NF1, FGFR1, KMT2D , (...)

View the complete list with 24 more genes
Specificity
3 %
Genes
100 %
CEN4GEN Ovarian cancer: Extended gene sequencing Panel.

By CEN4GEN Institute for Genomics and Molecular Diagnostics in Canada.

BRCA1, BRCA2, MSH2, MLH1, PTEN, TP53, RB1, CUBN, BRAF, KRAS, NRAS, CDKN2A, NF1, CTNNB1, ARID1A, KIT, PIK3CA, EGFR, PDGFRA, CBLC , (...)

View the complete list with 12 more genes
Specificity
4 %
Genes
100 %
CEN4GEN Prostate cancer: Extended gene sequencing Panel.

By CEN4GEN Institute for Genomics and Molecular Diagnostics in Canada.

APC, PTEN, TP53, RB1, ZFHX3, AR, CDKN2A, KMT2D, MED12, AKAP9, CDKN1B, PIK3CA, TBX20, SCN11A, CDK12, MYC, GLI1, KLF6, NIPA2, NKX3-1 , (...)

View the complete list with 8 more genes
Specificity
4 %
Genes
100 %
CEN4GEN Comprehensive Solid tumors (somatic genetic testing): Sequencing Panel.

By CEN4GEN Institute for Genomics and Molecular Diagnostics in Canada.

BRCA1, BRCA2, VHL, APC, PTEN, TP53, WT1, RB1, RET, IDH2, BRAF, HRAS, KRAS, NRAS, FGFR2, MAP2K2, ATM, PTCH1, STK11, CDKN2A , (...)

View the complete list with 12 more genes
Specificity
4 %
Genes
100 %
CEN4GEN Comprehensive targeted oncogene tumor mutation screen (somatic genetic testing): Sequencing Panel.

By CEN4GEN Institute for Genomics and Molecular Diagnostics in Canada.

VHL, APC, MLH1, PTEN, TP53, HNF1A, RB1, RET, FGFR3, BRAF, HRAS, KRAS, NRAS, PTPN11, FGFR2, ALK, ATM, CDH1, STK11, CDKN2A , (...)

View the complete list with 28 more genes
Specificity
3 %
Genes
100 %

Alternate names

Congenital Lipomatous Overgrowth, Vascular Malformations, And Epidermal Nevi Is also known as clove syndrome, congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and skeletal/spinal abnormalities, cloves syndrome;congenital lipomatous overgrowth-vascular malformation-epidermal nevi-skeletal anomaly syndrome; congenital lipomatous overgrowth-vascular malformation-epidermal nevi-spinal anomaly syndrome.



If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like OVARIAN HYPERSTIMULATION SYNDROME; OHSS CITRULLINEMIA, TYPE II, ADULT-ONSET; CTLN2 CREUTZFELDT-JAKOB DISEASE; CJD JUNCTIONAL EPIDERMOLYSIS BULLOSA INVERSA ACHROMATOPSIA 4; ACHM4

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